What is the best allergy medicine for dogs

After informed consent, subjects will be randomly assigned to ILIT group or placebo group in double-blind manner. In both group, causal allergen or placebo will be injected into inguinal lymph node through guidance by ultrasonography three times with 4-week interval. In ILIT group, initial dose of allergen will be 1,fold diluted solution from maximal concentration of allergen extract for subcutaneous immunotherapy (Tyrosine S, Allergy Therapeutic, West Sussex, UK) in volume of ml.

If skin is highly reactive in skin prick test, the initial dose will be fold dilution from maximal concentration where diameter of wheal is less than that of histamine. After the first dose, allergen concentration will be escalated 3-fold at second dose, and fold at third dose if there are no (or mild) local or systemic hypersensitivity reaction. The allergen concentration will not change at second or third dose if there is moderate local or systemic reaction. The allergen concentration will decrease by 10 or fold from previous concentration or further injection will be held if there is severe local or systemic reaction after sufficient explanation and discussion with subjects.

The investigators will assess allergic rhinitis symptom score before and 4, 12 months after the initial treatment.

Rhinoconjunctivitis Quality of Life Questionnaire (RQLQ) and Sino-Nasal Outcome Test (SNOT) will be used. Visual analogue scale (VAS) of symptoms including rhinorrhea, sneezing, nasal obstruction, postnasal drip, eye/nose/ear/palate itching, dyspnea, wheezing, chest discomfort as well as urticaria, angioedema, and itching on exposed skin during exposure to causal allergen in daily life will be also evaluated. Skin prick test (SPT), intradermal test (IDT), blood sampling for serum entire immunoglobulin E (IgE), allergen-specific IgE, and allergen-specific immunoglobulin G4 (IgG4), nasal lavage for Th1, Th2, and Treg cytokines, and nasal provocation test (NPT) with Df and/or Dp allergen (in subjects whose AR symptoms are provoked by Df and/or Dp) will be also performed before and 4, 12 months after the initial treatment.

In addition, the investigators evaluated the change of subjects’ recognition of causal allergens, their avoidance, and AIT during this study. Using VAS, subjects were requested to score the rate of agreement with "Allergen provokes allergic symptoms in daily life", "Allergen avoidance can reduce allergic symptoms", "Allergen-specific Immunotherapy (AIT) can reduce allergic symptoms", "I can pay 50, Korean Won (KRW)/month for allergen avoidance", "I can pay , KRW/month for allergen avoidance", "I can pay , KRW/month for allergen avoidance", "I can pay , KRW for each injection of ILIT", "I can pay , KRW for each injection of ILIT", "I can pay , KRW for each injection of ILIT" before and after SPT/IDT, after NPT, 4 months and 1 year after ILIT.

Adverse events will be recorded and graded according to Muller classification and Ring and Meissner classification.

Sarcoptic Mange: Save Your Dog’s Skin from Scabies

It sounds troubling, love something out of a gritty movie about the bad part of town: a dog walks by with mange, looking ragged, uncared-for and mad.

Well, you’d be mad and ragged too if tiny mites caused you to lose your hair and itch severely. Thankfully, mange is not as scary as you may own heard, and it’s easily treatable.

What is mange on dogs?

The illness we call “mange” on dogs is actually sarcoptic mange, also known as canine scabies. It’s not an illness but rather an infestation of microscopic mites – the parasite known as Sarcoptes scaeibi. While cats, foxes and even humans can get mange, these parasites particularly prefer dogs.

Once on a host dog, the mites cause several skin problems, most notably hair loss and severe itching.

What are the symptoms of sarcoptic mange?

The most obvious symptoms of sarcoptic mange is severe itching and hair loss. The mites prefer to live in areas with less hair, so itching is often concentrated on the dog’s elbows, ears, chest, armpits and stomach. As the infestation worsens, the itching and hair loss spreads.

The bites can also cause red pustules with yellow crusts.

If left untreated, the dog’s skin will start showing signs of severe irritation, such as redness and sores due to bacterial infections. In fact, some doctors believe the irritation dogs feel is actually an allergic reaction to the mites’ bites.

How is sarcoptic mange diagnosed on dogs?

It can be challenging for you or your veterinarian to diagnose sarcoptic mange. When mange is suspected, your vet will scrape the dog’s skin to glance for the scabies under a microscope.

Unfortunately, the mites only show up in about 20 percent of skin scrapings – so while a positive identification surely means the mites are present, a negative scraping does not really prove anything. Therefore, the most common way to diagnose a dog for mange is to discuss the dog’s history, note if allergy treatments own been effective or failed, and to start treatment for scabies. If the dog improves with treatment, then a diagnosis of scabies may be confirmed.

How do you treat canine scabies?

There are a few approaches to treating sarcoptic mange in dogs.

  • Allegra works within two hours and Zyrtec works within one hour.
  • Handa S, Dogra S, Kumar B.

    Comparative efficacy of cetirizine and fexofenadine in the treatment of chronic idiopathic urticaria.J Dermatolog Treat. Jan;15(1)

  • Allegra should not be taken with grapefruit juice. Zyrtec has no reported food interactions.
  • Meltzer EO, Caballero F, Fromer LM, Krouse JH, Scadding G. Treatment of congestion in upper respiratory diseases. International Journal of General Medicine. ;
  • Post-Nasal Drip.

    American Academy of Otolaryngology — Head and Neck Surgery.

  • Day JH1, Briscoe MP, Rafeiro E, et al. Comparative efficacy of cetirizine and fexofenadine for seasonal allergic rhinitis, hours postdose, in the environmental exposure unit. Allergy Asthma Proc. Jul-Aug;26(4)
  • Heartworm and flea prevention: Some vets will prescribe flea-prevention and heartworm-prevention medications love Revolution or Frontline to treat mange, but at the Animal Clinic of Woodruff, we own not seen these treatments to be effective in treating scabies. However, one medicine we’ve had success with at the Clinic is Bravecto. It’s a flea and tick prevention that is also effective at killing the scabies mite.

    We typically combine this medication with our bath protocol, but in mild cases, it may be used alone.

  • Studies own not compared the effects of Allegra and Zyrtec for conditions such as postnasal drip, but research suggests intranasal antihistamines such as azelastine are more effective.
  • Simon FER, Simons KJ. H1 Antihistamines: Current Status and Future Directions. The World Allergy Organization Journal. ;1(9) doi/
  • Slater JW1, Zechnich AD, Haxby -generation antihistamines: a comparative Jan;57(1)
  • Allergies: as with us, our pets can suffer from allergy-induced itchy, watery eyes 
  • Liquid ivermectin: This is a stronger version of the heartworm prevention medicine found in Heartguard.

    We will occasionally use this treatment, but it’s rarely a first choice. It should not be used for Collies, Shetland sheep dogs, or other herding breeds.

  • Zyrtec and Allegra should not be taken at the same time, instead, if symptoms are persisting, it is better to take another drug with a diverse mechanism of action.
  • Sharma M, Bennett C, Cohen SN, Carter B. H1-antihistamines for chronic spontaneous urticaria. Cochrane Database of Systematic Reviews , Issue Art. No.: CD DOI: /CDpub2
  • Banfield C, Gupta S, Marino M, et al. Grapefruit juice reduces the oral bioavailability of fexofenadine but not desloratadine.

    Clin Pharmacokinet. ;41(4)

  • Glaucoma: a much more serious condition caused by increased pressure within the eye itself
  • Entropion: when the eyelashes are turned inward instead of outward, causing the eye to tear, become irritated, and ultimately infected, if not treated
  • Conjunctivitis: the mucus membranes of the eye become inflamed and itchy (This is the most common eye problem among our four-legged friends.) 
  • Foreign body: a foreign object in the eye, even eyelashes, can cause the eye to be irritated
  • Mann RD, Pearce GL, Dunn N, Shakir S. Sedation with “non-sedating” antihistamines: four prescription-event monitoring studies in general practice.

    BMJ?: British Medical Journal. ;()

  • Scratched cornea: a scratch on the eye can develop into a more serious condition, such as an ulcer
  • Several studies own found cetirizine (Zyrtec) to be more effective than fexofenadine (Allegra) at relieving symptoms of allergic rhinitis and urticaria, and it appears to own a longer duration of action.
  • Medicinal baths: Our preferred and the most effective treatment is to bath the dog regularly in chemical shampoos.

    The dog will generally own his hair clipped short, then is dipped once/week for weeks. Unfortunately, the dip has a extremely foul smell and can be toxic to humans and vulnerable dogs, so grand care is needed in dipping dogs (and in treating their facial areas). When done correctly, the dips are extremely effectively.

  • Hampel F, Ratner P, Mansfield L, et al. Fexofenadine hydrochloride, mg, exhibits equivalent efficacy to cetirizine, 10 mg, with less drowsiness in patients with moderate-to-severe seasonal allergic rhinitis.

    Ann Allergy Asthma Immunol. Oct;91(4)

Along with treating the dog, the dog’s bedding and other areas can be treated with an insecticide. And since scabies is spread among dogs, other dogs in the home should be treated.

Finally, due to the trauma on the dog’s skin, your vet will likely also need to prescribe medications to treat bacterial skin infections and/or yeast infections, and will also propose products to relieve itchy, sore skin.

Can humans get mange?

There are human versions of scabies, but that is a diverse animal than Sarcoptes scaeibi, which lives on dogs.

That said, humans can contract scabies from pets, and might experience itching or rashes, especially on the wrists or hands. If you see a rash or are itchy while your dog has scabies, see your doctor immediately.

How can I prevent mange and scabies in dogs?

There’s no way to fully protect your dog, as scabies is spread by contact with other dogs. Take care when your dog is surrounded by lots of other dogs. You should hold your dog away from foxes and places where foxes go, as they can carry scabies that will carry to dogs.

If you suspect your dog may own mange, contact Animal Clinic of Woodruff today to make an appointment with our veterinarians in Woodruff.

Posted in Pet Health Issues

One of the most common medical complaints that we see in our office is dogs with skin infections, “hot spots”, or allergic dermatitis, also known as atopic (atopy) dermatitis.

Unlike people who react to allergens most commonly with nasal symptoms and/or hives, dogs react with skin and/or gastrointestinal problems.

This is because there are a higher proportion of mast cells, which release histamines and other vasoactive substances in the face of an allergic challenge, in the skin of dogs. These problems may range from poor jacket texture or hair length, to itching and chewing, to boiling spots and self-mutilation, gastrointestinal pain and discomfort, diarrhea, and flatulence. Allergies may also frolic a part in chronic ear infections. The most common causes of canine allergic dermatitis are flea allergy, food allergy, inhalant or contact allergy, and allergy to the normal bacterial flora and yeast organisms of the skin.

To make matters more hard to diagnose and treat, thyroid disease may add to the problem as well.

Canine atopic dermatitis (allergic dermatitis, canine atopy) is an inherited predisposition to develop allergic symptoms following repeated exposure to some otherwise harmless substance, an “allergen”. Most dogs start to show their allergic signs between 1 and 3 years of age. Due to the hereditary nature of the disease, several breeds, including Golden Retrievers, most terriers, Irish Setters, Lhasa Apsos, Dalmatians, Bulldogs, and Ancient English Sheep dogs are more commonly atopic, but numerous dogs, including mixed breed dogs can own atopic dermatitis. Atopic animals will generally rub, lick, chew, bite, or scratch at their feet, flanks, ears, armpits, or groin, causing patchy or inconsistent hair loss and reddening and thickening of the skin.

The skin itself may be dry and crusty or oily depending upon the dog. Dogs may also rub their face on the carpet; ear flaps may become red and boiling. Because the wax-producing glands of the ear overproduce as a response to the allergy, they get bacterial and yeast (Malassezia ) infections of the ear.

In order to overcome these frustrating symptoms, your veterinarian’s approach needs to be thorough and systematic. Shortcuts generally will not produce results and only add to owner frustration and canine discomfort.

Inhalant and Contact Allergies
Substances that can cause an allergic reaction in dogs are much the same as those that cause reactions in people including the pollens of grasses, trees and weeds, dust mites, and molds.

A clue to diagnosing these allergies is to glance at the timing of the reaction. Does it happen year round? This may be mold or dust. If the reaction is seasonal, pollens may be the culprit.

Food Allergies
Numerous people don’t suspect food allergies as the cause of their dog’s itching because their pet has been fed the same food every its life and has just recently started having symptoms. However, animals can develop allergies to a substance over time, so this fact does not law out food allergies.

Another common misconception is that dogs are only sensitive to poor quality food. If the dog is allergic to an ingredient, it doesn’t matter whether it is in premium food or the most inexpensive brand on the market. One advantage to premium foods is that some avoid common fillers that are often implicated in allergic reactions.

Flea Allergies
This type of reaction generally is not to the flea itself, but rather to proteins in its saliva. Interestingly enough, the dogs most prone to this problem are not dogs who are constantly flea ridden, but those who are exposed only occasionally! A single bite can cause a reaction for five to seven days, so you don’t need a lot of fleas to own a miserable dog.

Staphylococcus Hypersensitivity
Bacterial hypersensitivity occurs when a dog’s immune system overreacts to the normal Staphylococcus (Staph) bacteria on its skin.

It appears that bacterial hypersensitivity in the dog is more likely to happen if other conditions such as hypothyroidism, inhalant allergy, and/or flea allergy are concurrently present. Bacterial hypersensitivity is diagnosed through bacterial culture and examination of a biopsy sample. Microscopically, there are certain unique changes in the blood vessels of the skin in bacterial hypersensitivity.

Diagnosis

Allergy testing is the best diagnostic tool and the best road to treatment for dogs that are suffering from moderate and severe allergies.

There are several diverse testing methods available. The most common is a blood test that checks for antigen induced antibodies in the dog’s blood. Intradermal skin testing may also be performed. In this method of testing, a little quantity of antigen is injected into a shaved portion of the dog’s skin. This is done in a specific pattern and order so that if the dog shows a little raised reaction, the offending antigen can be identified.

After a period of time (hours), the shaved area is examined to detect which antigens, if any, created a reaction. Allergy testing is performed to develop a specific therapy for the allergic animal.

Treatment

Medicated Baths
Numerous medicated shampoos own compounds in them that are aimed at soothing injured skin and calming inflammation. In addition, frequent bathing (weekly to every other week) of the dog can remove allergens from the hair jacket, which may contribute to skin allergy flare-ups. The medicated baths we recommend are those that actually contain antimicrobial and antifungal agents as well as ingredients that permit the skin to be bathed on a more frequent basis without drying it out.

Application of a rinse afterwards also helps to prevent drying out of the skin and hair coat.

Antihistamines
Antihistamines can be used with excellent safety in dogs. About one third of owners report success with antihistamines.

What is the best allergy medicine for dogs

These medications tend to own a variable effect between dogs. For some allergic dogs, antihistamines work extremely well in controlling symptoms of allergic skin disease. For other dogs, extremely little effect is seen. Therefore, a minimum of three diverse types of antihistamines should be tried before owners give up on this therapy. Examples of antihistamines commonly used for dogs include Benadryl, Chlortrimeton, Atarax, Claritin, Zyrtec, and Clemastine. However, antihistamines are considered to be worth trying in most cases since the side effects associated with antihistamines is low, and they are typically inexpensive medications.

Antibiotics and Antifungal Medications
Antibiotics are frequently needed to treat secondary skin infections.

Anti-fungal medications are frequently needed to treat secondary yeast infections.

Flea Control
For dogs with this problem, a strict flea control regime must be maintained. The best flea control options include the use of products such as Advantage, Revolution, Frontline, Comfortis, and Sentinel.

Supplements
The Omega-3 and Omega-6 essential fatty acid supplements work by improving the overall health of the skin. These fatty acids are natural anti-inflammatory and anti-oxidative agents.

They reportedly are helpful in 20% of allergic dogs. My own experience puts this figure a little higher. They are certainly worth a attempt because they are not harmful and own virtually no side effects. Omega-3 fatty acids are found in fish oils and omega-6 fatty acids are derived from plants containing gamma-linolenic acid (GLA). These supplements are diverse from those sold to produce a glossy jacket. Products that contain both omega-3 and omega-6 fatty acids include Allergen Caps and Halo.

Hypoallergenic Diets
Allergies develop through exposure, so most hypoallergenic diets incorporate proteins and carbohydrates that your dog has never had before.

As mentioned previously, the quickest and best way to determine which foods your dog may or may not be allergic to is through diagnostic allergy testing. As dairy, beef, and wheat are responsible for 80% of food allergies in dogs, these items should be avoided. Novel protein sources used in hypoallergenic diets include venison, egg, duck, kangaroo, and types of fish not generally found in pet food. Carbohydrate sources include potatoes, peas, yams, sweet potatoes, and canned pumpkin.

Hydrolyzed protein diets are diets in which the protein source has been synthetically reduced to little fragments.

The theory behind feeding a hydrolyzed protein source is that the proteins in the food should be little enough that the allergic dog’s immune system will not recognize the protein fragments and will not mount an immune response resulting in an allergy.

Most pets with food allergies reply well when switched to a store-bought hypoallergenic diet, but occasionally an animal suffers from such extreme allergies that a homemade diet is the only option. In this case, the diet should be customized with the aid of a veterinarian.

Corticosteroids and Immunosuppressive Agents
Cortisone products such as prednisone, prednisolone, and dexamethasone reduce itching by reducing inflammation.

These medications are not without side effects, so they need to be used judiciously in treating skin allergies. Steroids should be considered only when the allergy season is short, the quantity of drug required is little, or to relieve a dog in extreme discomfort. Side effects can include increased thirst and appetite, increased need to urinate, and behavioral changes. Long-term use can result in diabetes and decreased resistance to infection.

In some dogs, endless term, low-dose alternate day therapy is the only management protocol that successfully controls the atopic pet. This protocol should be used only as a final resort after every other methods own been exhausted to avoid the potential long-term complications of the medication.

Cyclosporine (Atopica) is a medication, which seems to be fairly effective at reducing the inflammation associated with skin allergies and calming the immune system of the affected dog. However, the pricing of cyclosporine may be prohibitive for larger breed dogs.

Immunotherapy (Hypo-sensitization)
Allergy shots are extremely safe, and numerous people own grand success with them; however, they are extremely slow to work.

It may be six to twelve months before improvement is seen. Once the allergens for the dog are identified, an appropriate immunotherapy is manufactured for that specific dog, and treatment can start. After the offending antigens are identified, then a mixture of these antigens can be formulated into a hyposensitizing injection. Depending on the type of agents used, these injections will be given over a period of weeks to months until the dog or cat develops immunity to the agents. After initial protection, an occasional booster may own to be given.

Environmental Control
If you know which substances your dog is allergic to, avoidance is the best method of control.

Even if you are desensitizing the dog with allergy shots, it is best to avoid the allergen altogether. Molds can be reduced by using a dehumidifier or placing activated charcoal on top of the exposed dirt in your home plants. Dusts and pollens are best controlled by using an air cleaner with a HEPA filter. Air conditioning can also reduce circulating amounts of airborne allergens because windows are then kept closed.

Thyroid Medication
Healthy skin and a normal hair jacket are the results of numerous factors, both external and internal. There are several glands in the body responsible for the production of hormones that are vital for the regulation of other body functions as well as a normal skin surface and hair jacket.

Hypothyroidism may result in poor skin and hair jacket, including hair loss or abnormal hair turnover, dull or brittle hair, altered pigmentation, and oily or dry skin. A blood test is a simplest and most direct way to tell if your dog is hypothyroid. Thyroid testing may include every or part of the following:

Baseline T4 Test or Entire T4 (TT4): This is the most common test. Dogs with a failure of the thyroid gland will own a lowered level of the T4 hormone. However, there are other conditions that can cause the T4 to decrease, so if this test comes back positive for hypothyroidism your vet should recommend an additional blood test, either the T3 Test or the Baseline TSH test.

Baseline TSH Test: Measures the level of Thyroid Stimulating Hormone.

In combination with the T4 or T3 test, it provides a more finish picture of the hormonal activity of your dog’s thyroid gland.

Free T4 by RIA (radio immunoassay): The Free T4 test using RIA techniques does not appear to be more or less precise than the above TT4 test.

Free T4 by ED (equilibrium dialysis): This test may provide more precise data on the level of T4 hormone in your dog’s bloodstream.

Baseline T3 Test: In combination with the T4 or TSH test, these two blood tests can give a clearer picture of the hormone levels found in the bloodstream.

This test is not dependable when used alone. The T3 Test should always be given in combination with one of the other blood tests.

TSH Response Test: In this test, the veterinarian takes an initial measurement of the thyroid hormones in your dog’s bloodstream and then injects Thyroid Stimulating Hormone (TSH) into the vein. After 6 hours, a blood sample is drawn and the level of T4 is checked. If your dog has hypothyroidism, the level of T4 will not increase even after the TSH is injected. This is an expensive test and is being used less often due to decreased production by the manufacturers.

Hypothyroidism is treated with a daily dose of synthetic thyroid hormone called thyroxine (levothyroxine).

Blood samples will need to be drawn periodically to assess the effectiveness of the dosage and make any adjustments necessary.

Successful management of the atopic, allergic dog is sometimes complicated and frustrating because multi-modal management is necessary in the majority of cases to control the allergic flare-ups.

What is the best allergy medicine for dogs

Proper diagnosis by a veterinarian and owner compliance and follow up care is essential to maximize the chances of curing or at least controlling the severely affected allergy patient.



Overview
Your dog’s eye(s) can become inflamed for a variety of reasons, ranging from conditions that are simple to repair to some that are extremely serious.

Some of the most common are:

  1. Allergies: as with us, our pets can suffer from allergy-induced itchy, watery eyes 
  2. Scratched cornea: a scratch on the eye can develop into a more serious condition, such as an ulcer
  3. Glaucoma: a much more serious condition caused by increased pressure within the eye itself
  4. Foreign body: a foreign object in the eye, even eyelashes, can cause the eye to be irritated
  5. Conjunctivitis: the mucus membranes of the eye become inflamed and itchy (This is the most common eye problem among our four-legged friends.) 
  6. Entropion: when the eyelashes are turned inward instead of outward, causing the eye to tear, become irritated, and ultimately infected, if not treated

There are numerous less common eye conditions that can cause eye inflammation.

Your veterinarian will work to identify what is troubling your teary-eyed friend.

Symptoms
The most common sign your pooch’s eyes are irritated is redness. Additionally, she may blink or squint excessively, hold her eye closed, rub or paw at her eye, and her eye might tear a lot. There may also be some mucus or pus-like discharge around your dog’s eye(s).

Diagnosis/Treatment
If you ponder your pet’s eyes are irritated, you should contact your veterinarian for advice. Numerous of the most common situations need medical attention in order to get better. Your veterinarian will most likely act out a finish ophthalmic examination to determine the cause of the inflammation.

In more serious situations, they may send you to a dog eye expert, also referred to as a veterinary ophthalmologist.

Your veterinarian will advise you regarding the best way to care for your pet’s eye(s). One of the most common treatments is to apply medicated drops or ointment to the affected eye. Having your compadre sit still while you apply the medication can be challenging. For assist with this, watch an expert apply eye drops to a dog.

Prevention
Because there are so numerous diverse causes of eye inflammation, there is no single prevention that works for every situation.

To assist your dog reduce the risk of eye problems, check her eyes daily for any obvious signs of irritation, such as redness or tearing.

If you own any questions or concerns, you should always visit or call your veterinarian – they are your best resource to ensure the health and well-being of your pets.

Allegra and Zyrtec are both antihistamines, but is one more effective or less likely to cause sedation than the other?

Allegra has the lowest risk of sedation out of every antihistamines so is preferred if an antihistamine is needed for people working in safety-critical jobs.

Even though Zyrtec is times more likely to cause sedation than Allegra, it is still much less sedating than some older antihistamines such as promethazine.

Other differences:

  1. Studies own not compared the effects of Allegra and Zyrtec for conditions such as postnasal drip, but research suggests intranasal antihistamines such as azelastine are more effective.
  2. Allegra should not be taken with grapefruit juice. Zyrtec has no reported food interactions.
  3. Allegra works within two hours and Zyrtec works within one hour.
  4. Several studies own found cetirizine (Zyrtec) to be more effective than fexofenadine (Allegra) at relieving symptoms of allergic rhinitis and urticaria, and it appears to own a longer duration of action.
  5. Zyrtec and Allegra should not be taken at the same time, instead, if symptoms are persisting, it is better to take another drug with a diverse mechanism of action.

Allegra is a brand name for the drug fexofenadine and Zyrtec is a brand name for the drug cetirizine.

Both fexofenadine and cetirizine are favorite antihistamines with numerous similarities but there are some significant differences.

Which is more sedating? Allegra or Zyrtec?

Allegra (fexofenadine) and Zyrtec (cetirizine) are second-generation antihistamines. Second-generation antihistamines were first developed in the s to provide allergy relief without the unwanted side effect of sedation common to first-generation antihistamines such as promethazine and diphenhydramine.

However, it soon became apparent that not every second-generation antihistamines were equal when it came to not causing drowsiness or affecting other thought processes. Cetirizine is significantly more likely than fexofenadine to cause drowsiness.

Fexofenadine (Allegra), even in dosages exceeding those recommended, is the least sedating of every second-generation antihistamines, so is considered the antihistamine of choice for people in safety-critical jobs such as airline pilots.

Which is more effective for Allergic rhinitis?

Trials own shown both Allegra (fexofenadine) and Zyrtec (cetirizine) are significantly more effective than placebo (a pretend pill) for reducing symptoms associated with allergic rhinitis, hay fever, and other allergies.

Trials own not consistently shown that one antihistamine is more effective than another; however, one trial reported cetirizine produced a 26% greater reduction in the number of allergic rhinitis symptoms at 12 hours and 14% greater reduction in symptoms overall compared with fexofenadine. Cetirizine also appeared more effective for symptoms such as runny nose, sneezing, itchy/watery eyes, and itchy nose, mouth or throat.

Cetirizine was slightly more likely (%) than fexofenadine to cause drowsiness. Another trial reported similar findings (33% greater reduction in allergic rhinitis symptoms) and also found cetirizine had a longer duration of effect.

Intranasal or ophthalmic (into the eye) antihistamines own a quicker onset of action than oral antihistamines (within about 15 minutes); however, they need to be istered several times daily. In people with allergic rhinoconjunctivitis and predominantly eye symptoms, ophthalmic antihistamines work much quicker (within 3 to 15 minutes) and are much more effective than any other form of treatment. Intranasal antihistamines are as effective as intranasal cromolyn, intranasal nedocromil, and leukotriene modifiers in seasonal allergic rhinitis; however, are not as effective at relieving nasal congestion and other symptoms as intranasal glucocorticoids.

Allegra Vs Zyrtec for urticaria and other skin reactions

All second generation antihistamines, including Allegra and Zyrtec, are effective for acute and chronic urticaria, although more trials own been conducted in people with chronic urticaria.

One trial found cetirizine to be more effective than fexofenadine at relieving symptoms in 97 patients with chronic urticaria with % of participants taking cetirizine reporting themselves as symptom-free after 28 days of treatment compared with only % of participants taking fexofenadine. Partial improvement was reported by % of people assigned cetirizine (% assigned fexofenadine) and % experienced no improvement with cetirizine (% with fexofenadine).

No difference in side effects was noted between the two.

Allegra Vs Zyrtec for Postnasal Drip

Post nasal drip may happen for various reasons — allergies (particularly to dairy), colds or flu, various drugs (including birth control pills and high blood pressure tablets), freezing temperatures, bright lights, hormonal changes and spicy foods.

Thin postnasal drip secretions caused by allergies may be treated with antihistamines.

Second-generation antihistamines such as Allegra and Zyrtec may offer better relief than older-type antihistamines such as promethazine (older antihistamines tend to thicken post-nasal secretions). Intranasal antihistamines, such as azelastine, own a faster onset of action (15 minutes) and appear more effective than oral antihistamines although require more frequent istration. Other treatments include decongestants, cromolyn, and corticosteroid nasal sprays.

In the treatment of post nasal drip caused by nonallergic causes, oral second-generation antihistamines are not extremely effective.

However, the intranasal antihistamine azelastine is effective. Azelastine improves every rhinitis symptoms including nasal congestion, postnasal drip, sneezing and sleeping difficulty. The most common side effect is a metallic aftertaste; however, this is more likely at higher dosages and tends to dissipate with continued use.

Allegra Vs Zyrtec To Relieve Freezing Symptoms

Second-generation antihistamines (such as Allegra and Zyrtec) own limited effectiveness at relieving symptoms of freezing such as a runny nose and sneezing (only 45% of adults felt better after using them compared to 35% with placebo [a pretend pill]). Effects were only noticeable if used within the first two days of a freezing, use of antihistamines made no difference thereafter.

Allegra Vs Zyrtec: istration

The antihistamine effects of Allegra and Zyrtec final for at least 24 hours, therefore, they are both given once daily.

Fexofenadine, the athletic ingredient of Allegra works within two hours. Cetirizine, the athletic ingredient of Zyrtec works within one hour.

Allegra Vs Zyrtec: Side Effects, Interactions and Price

Side effects are generally mild with second-generation antihistamines and include a headache and rarely dry mouth, and nausea. Zyrtec is times more likely than Allegra to cause sedation; however, Zyrtec is still much less sedating than older antihistamines such as promethazine.

Side effects are generally mild with second-generation antihistamines and include a headache and rarely dry mouth, and nausea.

Every the second generation antihistamines currently on the market appear free from adverse cardiovascular effects. Few major interactions own been reported with either Allegra or Zyrtec; however, there is the possibility that side effects such as sedation, confusion, and mental alertness may be enhanced if given with other drugs with this side effect.

Grapefruit juice appears to decrease the rate and extent of absorption of fexofenadine (Allegra) by about 30%. Cetirizine (Zyrtec) has no reported interactions with grapefruit or grapefruit products. More studies are needed to determine if there are any interactions between second generation antihistamines and herbal products and other types of food.

Always speak with your doctor of pharmacist before using any drugs in combination.

Cost is similar for 30 Allegra and 30 Zyrtec tablets and both are available as generics.

See also: Compare Tool — Allegra vs Zyrtec

References

  1. Banfield C, Gupta S, Marino M, et al. Grapefruit juice reduces the oral bioavailability of fexofenadine but not desloratadine. Clin Pharmacokinet. ;41(4)
  2. Mann RD, Pearce GL, Dunn N, Shakir S. Sedation with “non-sedating” antihistamines: four prescription-event monitoring studies in general practice. BMJ?: British Medical Journal. ;()
  3. Sharma M, Bennett C, Cohen SN, Carter B.

    H1-antihistamines for chronic spontaneous urticaria. Cochrane Database of Systematic Reviews , Issue Art. No.: CD DOI: /CDpub2

  4. Meltzer EO, Caballero F, Fromer LM, Krouse JH, Scadding G. Treatment of congestion in upper respiratory diseases. International Journal of General Medicine. ;
  5. Day JH1, Briscoe MP, Rafeiro E, et al. Comparative efficacy of cetirizine and fexofenadine for seasonal allergic rhinitis, hours postdose, in the environmental exposure unit.

    Allergy Asthma Proc. Jul-Aug;26(4)

  6. Handa S, Dogra S, Kumar B. Comparative efficacy of cetirizine and fexofenadine in the treatment of chronic idiopathic urticaria.J Dermatolog Treat. Jan;15(1)
  7. Simon FER, Simons KJ. H1 Antihistamines: Current Status and Future Directions. The World Allergy Organization Journal. ;1(9) doi/
  8. Post-Nasal Drip. American Academy of Otolaryngology — Head and Neck Surgery.
  9. Slater JW1, Zechnich AD, Haxby -generation antihistamines: a comparative Jan;57(1)
  10. Hampel F, Ratner P, Mansfield L, et al.

    Fexofenadine hydrochloride, mg, exhibits equivalent efficacy to cetirizine, 10 mg, with less drowsiness in patients with moderate-to-severe seasonal allergic rhinitis. Ann Allergy Asthma Immunol. Oct;91(4)

Along with treating the dog, the dog’s bedding and other areas can be treated with an insecticide. And since scabies is spread among dogs, other dogs in the home should be treated.

Finally, due to the trauma on the dog’s skin, your vet will likely also need to prescribe medications to treat bacterial skin infections and/or yeast infections, and will also propose products to relieve itchy, sore skin.

Can humans get mange?

There are human versions of scabies, but that is a diverse animal than Sarcoptes scaeibi, which lives on dogs.

That said, humans can contract scabies from pets, and might experience itching or rashes, especially on the wrists or hands. If you see a rash or are itchy while your dog has scabies, see your doctor immediately.

How can I prevent mange and scabies in dogs?

There’s no way to fully protect your dog, as scabies is spread by contact with other dogs. Take care when your dog is surrounded by lots of other dogs.

You should hold your dog away from foxes and places where foxes go, as they can carry scabies that will carry to dogs.

If you suspect your dog may own mange, contact Animal Clinic of Woodruff today to make an appointment with our veterinarians in Woodruff.

Posted in Pet Health Issues

One of the most common medical complaints that we see in our office is dogs with skin infections, “hot spots”, or allergic dermatitis, also known as atopic (atopy) dermatitis.

Unlike people who react to allergens most commonly with nasal symptoms and/or hives, dogs react with skin and/or gastrointestinal problems.

This is because there are a higher proportion of mast cells, which release histamines and other vasoactive substances in the face of an allergic challenge, in the skin of dogs. These problems may range from poor jacket texture or hair length, to itching and chewing, to boiling spots and self-mutilation, gastrointestinal pain and discomfort, diarrhea, and flatulence. Allergies may also frolic a part in chronic ear infections. The most common causes of canine allergic dermatitis are flea allergy, food allergy, inhalant or contact allergy, and allergy to the normal bacterial flora and yeast organisms of the skin. To make matters more hard to diagnose and treat, thyroid disease may add to the problem as well.

Canine atopic dermatitis (allergic dermatitis, canine atopy) is an inherited predisposition to develop allergic symptoms following repeated exposure to some otherwise harmless substance, an “allergen”.

Most dogs start to show their allergic signs between 1 and 3 years of age. Due to the hereditary nature of the disease, several breeds, including Golden Retrievers, most terriers, Irish Setters, Lhasa Apsos, Dalmatians, Bulldogs, and Ancient English Sheep dogs are more commonly atopic, but numerous dogs, including mixed breed dogs can own atopic dermatitis. Atopic animals will generally rub, lick, chew, bite, or scratch at their feet, flanks, ears, armpits, or groin, causing patchy or inconsistent hair loss and reddening and thickening of the skin. The skin itself may be dry and crusty or oily depending upon the dog. Dogs may also rub their face on the carpet; ear flaps may become red and boiling.

Because the wax-producing glands of the ear overproduce as a response to the allergy, they get bacterial and yeast (Malassezia ) infections of the ear.

In order to overcome these frustrating symptoms, your veterinarian’s approach needs to be thorough and systematic. Shortcuts generally will not produce results and only add to owner frustration and canine discomfort.

Inhalant and Contact Allergies
Substances that can cause an allergic reaction in dogs are much the same as those that cause reactions in people including the pollens of grasses, trees and weeds, dust mites, and molds.

A clue to diagnosing these allergies is to glance at the timing of the reaction. Does it happen year round? This may be mold or dust. If the reaction is seasonal, pollens may be the culprit.

Food Allergies
Numerous people don’t suspect food allergies as the cause of their dog’s itching because their pet has been fed the same food every its life and has just recently started having symptoms. However, animals can develop allergies to a substance over time, so this fact does not law out food allergies.

Another common misconception is that dogs are only sensitive to poor quality food. If the dog is allergic to an ingredient, it doesn’t matter whether it is in premium food or the most inexpensive brand on the market. One advantage to premium foods is that some avoid common fillers that are often implicated in allergic reactions.

Flea Allergies
This type of reaction generally is not to the flea itself, but rather to proteins in its saliva. Interestingly enough, the dogs most prone to this problem are not dogs who are constantly flea ridden, but those who are exposed only occasionally!

A single bite can cause a reaction for five to seven days, so you don’t need a lot of fleas to own a miserable dog.

Staphylococcus Hypersensitivity
Bacterial hypersensitivity occurs when a dog’s immune system overreacts to the normal Staphylococcus (Staph) bacteria on its skin. It appears that bacterial hypersensitivity in the dog is more likely to happen if other conditions such as hypothyroidism, inhalant allergy, and/or flea allergy are concurrently present.

Bacterial hypersensitivity is diagnosed through bacterial culture and examination of a biopsy sample.

What is the best allergy medicine for dogs

Microscopically, there are certain unique changes in the blood vessels of the skin in bacterial hypersensitivity.

Diagnosis

Allergy testing is the best diagnostic tool and the best road to treatment for dogs that are suffering from moderate and severe allergies. There are several diverse testing methods available. The most common is a blood test that checks for antigen induced antibodies in the dog’s blood. Intradermal skin testing may also be performed. In this method of testing, a little quantity of antigen is injected into a shaved portion of the dog’s skin.

What is the best allergy medicine for dogs

This is done in a specific pattern and order so that if the dog shows a little raised reaction, the offending antigen can be identified. After a period of time (hours), the shaved area is examined to detect which antigens, if any, created a reaction. Allergy testing is performed to develop a specific therapy for the allergic animal.

Treatment

Medicated Baths
Numerous medicated shampoos own compounds in them that are aimed at soothing injured skin and calming inflammation.

In addition, frequent bathing (weekly to every other week) of the dog can remove allergens from the hair jacket, which may contribute to skin allergy flare-ups. The medicated baths we recommend are those that actually contain antimicrobial and antifungal agents as well as ingredients that permit the skin to be bathed on a more frequent basis without drying it out. Application of a rinse afterwards also helps to prevent drying out of the skin and hair coat.

Antihistamines
Antihistamines can be used with excellent safety in dogs.

About one third of owners report success with antihistamines. These medications tend to own a variable effect between dogs. For some allergic dogs, antihistamines work extremely well in controlling symptoms of allergic skin disease. For other dogs, extremely little effect is seen. Therefore, a minimum of three diverse types of antihistamines should be tried before owners give up on this therapy. Examples of antihistamines commonly used for dogs include Benadryl, Chlortrimeton, Atarax, Claritin, Zyrtec, and Clemastine. However, antihistamines are considered to be worth trying in most cases since the side effects associated with antihistamines is low, and they are typically inexpensive medications.

Antibiotics and Antifungal Medications
Antibiotics are frequently needed to treat secondary skin infections.

Anti-fungal medications are frequently needed to treat secondary yeast infections.

Flea Control
For dogs with this problem, a strict flea control regime must be maintained. The best flea control options include the use of products such as Advantage, Revolution, Frontline, Comfortis, and Sentinel.

Supplements
The Omega-3 and Omega-6 essential fatty acid supplements work by improving the overall health of the skin. These fatty acids are natural anti-inflammatory and anti-oxidative agents.

They reportedly are helpful in 20% of allergic dogs. My own experience puts this figure a little higher. They are certainly worth a attempt because they are not harmful and own virtually no side effects. Omega-3 fatty acids are found in fish oils and omega-6 fatty acids are derived from plants containing gamma-linolenic acid (GLA). These supplements are diverse from those sold to produce a glossy jacket. Products that contain both omega-3 and omega-6 fatty acids include Allergen Caps and Halo.

Hypoallergenic Diets
Allergies develop through exposure, so most hypoallergenic diets incorporate proteins and carbohydrates that your dog has never had before.

As mentioned previously, the quickest and best way to determine which foods your dog may or may not be allergic to is through diagnostic allergy testing. As dairy, beef, and wheat are responsible for 80% of food allergies in dogs, these items should be avoided. Novel protein sources used in hypoallergenic diets include venison, egg, duck, kangaroo, and types of fish not generally found in pet food. Carbohydrate sources include potatoes, peas, yams, sweet potatoes, and canned pumpkin.

Hydrolyzed protein diets are diets in which the protein source has been synthetically reduced to little fragments.

The theory behind feeding a hydrolyzed protein source is that the proteins in the food should be little enough that the allergic dog’s immune system will not recognize the protein fragments and will not mount an immune response resulting in an allergy.

Most pets with food allergies reply well when switched to a store-bought hypoallergenic diet, but occasionally an animal suffers from such extreme allergies that a homemade diet is the only option. In this case, the diet should be customized with the aid of a veterinarian.

Corticosteroids and Immunosuppressive Agents
Cortisone products such as prednisone, prednisolone, and dexamethasone reduce itching by reducing inflammation.

These medications are not without side effects, so they need to be used judiciously in treating skin allergies. Steroids should be considered only when the allergy season is short, the quantity of drug required is little, or to relieve a dog in extreme discomfort. Side effects can include increased thirst and appetite, increased need to urinate, and behavioral changes. Long-term use can result in diabetes and decreased resistance to infection. In some dogs, endless term, low-dose alternate day therapy is the only management protocol that successfully controls the atopic pet. This protocol should be used only as a final resort after every other methods own been exhausted to avoid the potential long-term complications of the medication.

Cyclosporine (Atopica) is a medication, which seems to be fairly effective at reducing the inflammation associated with skin allergies and calming the immune system of the affected dog.

However, the pricing of cyclosporine may be prohibitive for larger breed dogs.

Immunotherapy (Hypo-sensitization)
Allergy shots are extremely safe, and numerous people own grand success with them; however, they are extremely slow to work. It may be six to twelve months before improvement is seen. Once the allergens for the dog are identified, an appropriate immunotherapy is manufactured for that specific dog, and treatment can start. After the offending antigens are identified, then a mixture of these antigens can be formulated into a hyposensitizing injection. Depending on the type of agents used, these injections will be given over a period of weeks to months until the dog or cat develops immunity to the agents.

After initial protection, an occasional booster may own to be given.

Environmental Control
If you know which substances your dog is allergic to, avoidance is the best method of control. Even if you are desensitizing the dog with allergy shots, it is best to avoid the allergen altogether. Molds can be reduced by using a dehumidifier or placing activated charcoal on top of the exposed dirt in your home plants. Dusts and pollens are best controlled by using an air cleaner with a HEPA filter. Air conditioning can also reduce circulating amounts of airborne allergens because windows are then kept closed.

Thyroid Medication
Healthy skin and a normal hair jacket are the results of numerous factors, both external and internal.

There are several glands in the body responsible for the production of hormones that are vital for the regulation of other body functions as well as a normal skin surface and hair jacket. Hypothyroidism may result in poor skin and hair jacket, including hair loss or abnormal hair turnover, dull or brittle hair, altered pigmentation, and oily or dry skin. A blood test is a simplest and most direct way to tell if your dog is hypothyroid. Thyroid testing may include every or part of the following:

Baseline T4 Test or Entire T4 (TT4): This is the most common test. Dogs with a failure of the thyroid gland will own a lowered level of the T4 hormone. However, there are other conditions that can cause the T4 to decrease, so if this test comes back positive for hypothyroidism your vet should recommend an additional blood test, either the T3 Test or the Baseline TSH test.

Baseline TSH Test: Measures the level of Thyroid Stimulating Hormone.

In combination with the T4 or T3 test, it provides a more finish picture of the hormonal activity of your dog’s thyroid gland.

Free T4 by RIA (radio immunoassay): The Free T4 test using RIA techniques does not appear to be more or less precise than the above TT4 test.

Free T4 by ED (equilibrium dialysis): This test may provide more precise data on the level of T4 hormone in your dog’s bloodstream.

Baseline T3 Test: In combination with the T4 or TSH test, these two blood tests can give a clearer picture of the hormone levels found in the bloodstream. This test is not dependable when used alone. The T3 Test should always be given in combination with one of the other blood tests.

TSH Response Test: In this test, the veterinarian takes an initial measurement of the thyroid hormones in your dog’s bloodstream and then injects Thyroid Stimulating Hormone (TSH) into the vein.

After 6 hours, a blood sample is drawn and the level of T4 is checked. If your dog has hypothyroidism, the level of T4 will not increase even after the TSH is injected. This is an expensive test and is being used less often due to decreased production by the manufacturers.

Hypothyroidism is treated with a daily dose of synthetic thyroid hormone called thyroxine (levothyroxine). Blood samples will need to be drawn periodically to assess the effectiveness of the dosage and make any adjustments necessary.

Successful management of the atopic, allergic dog is sometimes complicated and frustrating because multi-modal management is necessary in the majority of cases to control the allergic flare-ups.

Proper diagnosis by a veterinarian and owner compliance and follow up care is essential to maximize the chances of curing or at least controlling the severely affected allergy patient.



Overview
Your dog’s eye(s) can become inflamed for a variety of reasons, ranging from conditions that are simple to repair to some that are extremely serious.

Some of the most common are:

  1. Allergies: as with us, our pets can suffer from allergy-induced itchy, watery eyes 
  2. Scratched cornea: a scratch on the eye can develop into a more serious condition, such as an ulcer
  3. Glaucoma: a much more serious condition caused by increased pressure within the eye itself
  4. Foreign body: a foreign object in the eye, even eyelashes, can cause the eye to be irritated
  5. Conjunctivitis: the mucus membranes of the eye become inflamed and itchy (This is the most common eye problem among our four-legged friends.) 
  6. Entropion: when the eyelashes are turned inward instead of outward, causing the eye to tear, become irritated, and ultimately infected, if not treated

There are numerous less common eye conditions that can cause eye inflammation.

Your veterinarian will work to identify what is troubling your teary-eyed friend.

Symptoms
The most common sign your pooch’s eyes are irritated is redness. Additionally, she may blink or squint excessively, hold her eye closed, rub or paw at her eye, and her eye might tear a lot. There may also be some mucus or pus-like discharge around your dog’s eye(s).

Diagnosis/Treatment
If you ponder your pet’s eyes are irritated, you should contact your veterinarian for advice. Numerous of the most common situations need medical attention in order to get better.

Your veterinarian will most likely act out a finish ophthalmic examination to determine the cause of the inflammation. In more serious situations, they may send you to a dog eye expert, also referred to as a veterinary ophthalmologist.

Your veterinarian will advise you regarding the best way to care for your pet’s eye(s). One of the most common treatments is to apply medicated drops or ointment to the affected eye. Having your compadre sit still while you apply the medication can be challenging.

For assist with this, watch an expert apply eye drops to a dog.

Prevention
Because there are so numerous diverse causes of eye inflammation, there is no single prevention that works for every situation. To assist your dog reduce the risk of eye problems, check her eyes daily for any obvious signs of irritation, such as redness or tearing.

If you own any questions or concerns, you should always visit or call your veterinarian – they are your best resource to ensure the health and well-being of your pets.

Allegra and Zyrtec are both antihistamines, but is one more effective or less likely to cause sedation than the other?

Allegra has the lowest risk of sedation out of every antihistamines so is preferred if an antihistamine is needed for people working in safety-critical jobs.

Even though Zyrtec is times more likely to cause sedation than Allegra, it is still much less sedating than some older antihistamines such as promethazine.

Other differences:

  1. Studies own not compared the effects of Allegra and Zyrtec for conditions such as postnasal drip, but research suggests intranasal antihistamines such as azelastine are more effective.
  2. Allegra should not be taken with grapefruit juice. Zyrtec has no reported food interactions.
  3. Allegra works within two hours and Zyrtec works within one hour.
  4. Several studies own found cetirizine (Zyrtec) to be more effective than fexofenadine (Allegra) at relieving symptoms of allergic rhinitis and urticaria, and it appears to own a longer duration of action.
  5. Zyrtec and Allegra should not be taken at the same time, instead, if symptoms are persisting, it is better to take another drug with a diverse mechanism of action.

Allegra is a brand name for the drug fexofenadine and Zyrtec is a brand name for the drug cetirizine.

Both fexofenadine and cetirizine are favorite antihistamines with numerous similarities but there are some significant differences.

Which is more sedating? Allegra or Zyrtec?

Allegra (fexofenadine) and Zyrtec (cetirizine) are second-generation antihistamines. Second-generation antihistamines were first developed in the s to provide allergy relief without the unwanted side effect of sedation common to first-generation antihistamines such as promethazine and diphenhydramine.

However, it soon became apparent that not every second-generation antihistamines were equal when it came to not causing drowsiness or affecting other thought processes. Cetirizine is significantly more likely than fexofenadine to cause drowsiness.

Fexofenadine (Allegra), even in dosages exceeding those recommended, is the least sedating of every second-generation antihistamines, so is considered the antihistamine of choice for people in safety-critical jobs such as airline pilots.

Which is more effective for Allergic rhinitis?

Trials own shown both Allegra (fexofenadine) and Zyrtec (cetirizine) are significantly more effective than placebo (a pretend pill) for reducing symptoms associated with allergic rhinitis, hay fever, and other allergies.

Trials own not consistently shown that one antihistamine is more effective than another; however, one trial reported cetirizine produced a 26% greater reduction in the number of allergic rhinitis symptoms at 12 hours and 14% greater reduction in symptoms overall compared with fexofenadine. Cetirizine also appeared more effective for symptoms such as runny nose, sneezing, itchy/watery eyes, and itchy nose, mouth or throat. Cetirizine was slightly more likely (%) than fexofenadine to cause drowsiness. Another trial reported similar findings (33% greater reduction in allergic rhinitis symptoms) and also found cetirizine had a longer duration of effect.

Intranasal or ophthalmic (into the eye) antihistamines own a quicker onset of action than oral antihistamines (within about 15 minutes); however, they need to be istered several times daily.

In people with allergic rhinoconjunctivitis and predominantly eye symptoms, ophthalmic antihistamines work much quicker (within 3 to 15 minutes) and are much more effective than any other form of treatment. Intranasal antihistamines are as effective as intranasal cromolyn, intranasal nedocromil, and leukotriene modifiers in seasonal allergic rhinitis; however, are not as effective at relieving nasal congestion and other symptoms as intranasal glucocorticoids.

Allegra Vs Zyrtec for urticaria and other skin reactions

All second generation antihistamines, including Allegra and Zyrtec, are effective for acute and chronic urticaria, although more trials own been conducted in people with chronic urticaria.

One trial found cetirizine to be more effective than fexofenadine at relieving symptoms in 97 patients with chronic urticaria with % of participants taking cetirizine reporting themselves as symptom-free after 28 days of treatment compared with only % of participants taking fexofenadine. Partial improvement was reported by % of people assigned cetirizine (% assigned fexofenadine) and % experienced no improvement with cetirizine (% with fexofenadine). No difference in side effects was noted between the two.

Allegra Vs Zyrtec for Postnasal Drip

Post nasal drip may happen for various reasons — allergies (particularly to dairy), colds or flu, various drugs (including birth control pills and high blood pressure tablets), freezing temperatures, bright lights, hormonal changes and spicy foods.

Thin postnasal drip secretions caused by allergies may be treated with antihistamines.

Second-generation antihistamines such as Allegra and Zyrtec may offer better relief than older-type antihistamines such as promethazine (older antihistamines tend to thicken post-nasal secretions). Intranasal antihistamines, such as azelastine, own a faster onset of action (15 minutes) and appear more effective than oral antihistamines although require more frequent istration. Other treatments include decongestants, cromolyn, and corticosteroid nasal sprays.

In the treatment of post nasal drip caused by nonallergic causes, oral second-generation antihistamines are not extremely effective. However, the intranasal antihistamine azelastine is effective.

Azelastine improves every rhinitis symptoms including nasal congestion, postnasal drip, sneezing and sleeping difficulty. The most common side effect is a metallic aftertaste; however, this is more likely at higher dosages and tends to dissipate with continued use.

Allegra Vs Zyrtec To Relieve Freezing Symptoms

Second-generation antihistamines (such as Allegra and Zyrtec) own limited effectiveness at relieving symptoms of freezing such as a runny nose and sneezing (only 45% of adults felt better after using them compared to 35% with placebo [a pretend pill]). Effects were only noticeable if used within the first two days of a freezing, use of antihistamines made no difference thereafter.

Allegra Vs Zyrtec: istration

The antihistamine effects of Allegra and Zyrtec final for at least 24 hours, therefore, they are both given once daily.

What is the best allergy medicine for dogs

Fexofenadine, the athletic ingredient of Allegra works within two hours. Cetirizine, the athletic ingredient of Zyrtec works within one hour.

Allegra Vs Zyrtec: Side Effects, Interactions and Price

Side effects are generally mild with second-generation antihistamines and include a headache and rarely dry mouth, and nausea. Zyrtec is times more likely than Allegra to cause sedation; however, Zyrtec is still much less sedating than older antihistamines such as promethazine.

Side effects are generally mild with second-generation antihistamines and include a headache and rarely dry mouth, and nausea.

Every the second generation antihistamines currently on the market appear free from adverse cardiovascular effects. Few major interactions own been reported with either Allegra or Zyrtec; however, there is the possibility that side effects such as sedation, confusion, and mental alertness may be enhanced if given with other drugs with this side effect.

Grapefruit juice appears to decrease the rate and extent of absorption of fexofenadine (Allegra) by about 30%. Cetirizine (Zyrtec) has no reported interactions with grapefruit or grapefruit products. More studies are needed to determine if there are any interactions between second generation antihistamines and herbal products and other types of food.

Always speak with your doctor of pharmacist before using any drugs in combination.

Cost is similar for 30 Allegra and 30 Zyrtec tablets and both are available as generics.

See also: Compare Tool — Allegra vs Zyrtec

References

  1. Banfield C, Gupta S, Marino M, et al. Grapefruit juice reduces the oral bioavailability of fexofenadine but not desloratadine. Clin Pharmacokinet. ;41(4)
  2. Mann RD, Pearce GL, Dunn N, Shakir S. Sedation with “non-sedating” antihistamines: four prescription-event monitoring studies in general practice. BMJ?: British Medical Journal. ;()
  3. Sharma M, Bennett C, Cohen SN, Carter B. H1-antihistamines for chronic spontaneous urticaria.

    Cochrane Database of Systematic Reviews , Issue Art. No.: CD DOI: /CDpub2

  4. Meltzer EO, Caballero F, Fromer LM, Krouse JH, Scadding G. Treatment of congestion in upper respiratory diseases. International Journal of General Medicine. ;
  5. Day JH1, Briscoe MP, Rafeiro E, et al. Comparative efficacy of cetirizine and fexofenadine for seasonal allergic rhinitis, hours postdose, in the environmental exposure unit. Allergy Asthma Proc. Jul-Aug;26(4)
  6. Handa S, Dogra S, Kumar B. Comparative efficacy of cetirizine and fexofenadine in the treatment of chronic idiopathic urticaria.J Dermatolog Treat.

    Jan;15(1)

  7. Simon FER, Simons KJ. H1 Antihistamines: Current Status and Future Directions. The World Allergy Organization Journal. ;1(9) doi/
  8. Post-Nasal Drip. American Academy of Otolaryngology — Head and Neck Surgery.

    What is the best allergy medicine for dogs

  9. Slater JW1, Zechnich AD, Haxby -generation antihistamines: a comparative Jan;57(1)
  10. Hampel F, Ratner P, Mansfield L, et al. Fexofenadine hydrochloride, mg, exhibits equivalent efficacy to cetirizine, 10 mg, with less drowsiness in patients with moderate-to-severe seasonal allergic rhinitis. Ann Allergy Asthma Immunol. Oct;91(4)


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