What is ragweed allergies

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href=’/help/entry_name’ target=’_top’>More</a></p>Entry namei MPA5A_AMBPS
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href=’/help/accession_numbers’ target=’_top’>More</a></p>Accessioni PPrimary (citable) accession number: P
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the final sequence update and the date of the final annotation modification (‘Last modified’).

The version number for both the entry and the <a href=»»>canonical sequence</a> are also displayed.<p><a href=’/help/entry_history’ target=’_top’>More</a></p>Entry historyi

Integrated into UniProtKB/Swiss-Prot: November 1,
Last sequence update: November 1,
Last modified: December 11,
This is version 55 of the entry and version 1 of the sequence. See finish history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href=’/help/entry_status’ target=’_top’>More</a></p>Entry statusi Reviewed (UniProtKB/Swiss-Prot)
Annotation program Plant Protein Annotation Program


<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at diverse levels of sequence identity thresholds (%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href=»»>UniRef</a>).<p><a href=’/help/similar_proteins_section’ target=’_top’>More</a></p>Similar proteinsi

Full view


<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href=’/help/miscellaneous_section’ target=’_top’>More</a></p>Miscellaneousi

Keywords — Technical termi

Direct protein sequencing

Documents

  • Allergens
    Nomenclature of allergens and list of entries

Kitzmuller C, Kalser J, Mutschlechner S, Hauser M, Zlabinger GJ, Ferreira F, Bohle B.

Fusion proteins of flagellin and the major birch pollen allergen Bet v 1 show enhanced immunogenicity, reduced allergenicity, and intrinsic adjuvanticity. J Allergy Clin Immunol , , doi: /

Pablos I, Eichhorn S, Machado Y, Briza P, Neunkirchner A, Jahn-Schmid B, Wildner S, Soh WT, Ebner C, Park JW, Pickl W, Arora N, Vieths, S, Ferreira F, Gadermaier G. Distinct epitope structures of defensin-like proteins linked to proline-rich regions give rise to diferrences in their allergenic activity. Allergy , doi: /all

Strasser L, Dang HH, Schwarz H, Asam C, Ferreira F, Horejs-Hoeck J, Huber CG. Unbiased quantitative proteomics reveals a crucial role of the allergen context for the activation of human dendritic cells.

Scientific Rep , doi: /s

Wolf M, Aglas L, Twaroch TE, Steiner M, Huber S, Hauser M, Parigiani MA, Hofer H, Ebner C, Bohle B, Briza P, Nubauer A, Stolz F, Wallner M, Ferreira F. Endolysosomal protease susceptibility of Amb a 1 as a determinant of allergenicity. J Allergy Clin Immunol (epub ahead of print). doi: /

Schülke S, Kuttich K, Wolfheimer S, Duschek N, Wangorsch A, Reuter A, Briza P, Pablos I, Gadermaier G, Ferreira F, Vieths S, Toda M, Scheurer S. Conjugation of wildtype and hypoallergenic mugwort allergen Art v 1 to flagellin induces ILDC and suppresses allergen-specific TH2-responses in vivo.

Scientific Rep , doi: /sw

Zulehner N, Nagl B, Briza P, Roulias A, Ballmer-Weber B, Zlabinger GJ, Ferreira F, Bohle B. Characterization of the T-cell response to Dau c 1, the Bet v 1-homolog in carrot. Allergy , /all

Wolf M, Twaroch TE, Huber S, Reithofer M, Steiner M, Aglas L, Hauser M, Aloisi I, Asam C, Hofer H, Parigiani MA, Ebner C, Bohle B, Briza P, Neubauer A, Stolz F, Jahn-Schmid B, Wallner M, Ferreira F. Amb a 1 isoforms: Unequal siblings with distinct immunological features. Allergy , /all/all

Stemeseder T, Freier R, Wildner S, Fuchs JE, Briza P, Lang R, Batanero E, Lidholm J, Liedl KR, Campo P, Hawranek T, Villalba M, Brandstetter H, Ferreira F, Gadermaier G.

Crystal structure of Pla l 1 reveals both structural similarity and allergenic divergence within the Ole e 1-like protein family. J Allergy Clin Immunol , /

Santos da Silva E, Asam C, Lackner P, Hofer H, Wallner M, Silva Pinheiro C, Alcantara-Neves NM, Ferreira F. Allergens of Blomia tropicalis: An Overview of Recombinant Molecules. Int Arch Allergy Immunol , /

Soh WT, Briza P, Dall E, Asam C, Schubert M, Huber S, Aglas L, Bohle B, Ferreira F, Brandstetter H. Two Distinct Conformations in Bet v 2 Determine Its Proteolytic Resistance to Cathepsin S.

Int J Mol Sci. , pii:E doi: /ijms

Sancho AI, Wallner M, Hauser M, Nagl B, Himly M, Asam C, Ebner C, Jahn-Schmid B, Bohle B, Ferreira F. T Cell Epitope-Containing Domains of Ragweed Amb a 1 and Mugwort Art v 6 Modulate Immunologic Responses in Humans and Mice. PLoS One , e /

Pablos I, Eichhorn S, Briza P, Asam C, Gartner U, Wolf M, Ebner C, Bohle B, Arora N, Vieths S, Ferreira F, Gadermaier G. Proteomic profiling of the weed feverfew, a neglected pollen allergen source.

Sci Rep , 7: /sz

McKenna OE, Posselt G, Briza P, Lackner P, Schmitt AO, Gadermaier G, Wessler S, Ferreira F. Multi-Approach Analysis for the Identification of Proteases within Birch Pollen. Int J Mol Sci , /ijms

Hollbacher B, Schmitt AO, Hofer H, Ferreira F, Lackner P. Identification of Proteases and Protease Inhibitors in Allergenic and Non-Allergenic Pollen. Int J Mol Sci , /ijms

Hofer H, Asam C, Hauser M, Nagl B, Laimer J, Himly M, Briza P, Ebner C, Lang R, Hawranek T, Bohle B, Lackner P, Ferreira F, Wallner M.

Tackling Bet v 1 and associated food allergies with a single hybrid protein. J Allergy Clin Immunol , e /

Hirschl S, Ralser C, Asam C, Gangitano A, Huber S, Ebner C, Bohle B, Wolf M, Briza P, Ferreira F, Griesbeck C, Wallner M. Expression and Characterization of Functional Recombinant Bet v in the Chloroplast of Chlamydomonas reinhardtii. Int Arch Allergy Immunol , /

Ahammer L, Grutsch S, Wallner M, Ferreira F, Tollinger M. NMR resonance assignments of a hypoallergenic isoform of the major birch pollen allergen Bet v 1.

Biomol NMR Assign , , doi: /s

Wildner S, Elsässer B, Stemeseder T, Briza P, Soh WT, Villalba M, Lidholm J, Brandstetter H, Gadermaier G. Endolysosomal Degradation of Allergenic Ole e 1-Like Proteins: Analysis of Proteolytic Cleavage Sites Revealing T Cell Epitope-Containing Peptides Int J Mol Sci. Aug 16;18(8). pii: E

Stemeseder T, Klinglmayr E, Moser S, Lang R, Himly M, Oostingh GJ, Zumbach J, Bathke AC, Hawranek T, Gadermaier G. Influence of intrinsic and lifestyle factors on the development of IgE sensitization. Int Arch Allergy Immunol. ;(2)

Stemeseder T, Schweidler B, Doppler P, Klinglmayr E, Moser S, Lueftenegger L, Himly M, Lang R, Zumbach J, Oostingh GJ, Hawranek T, Bathke AC, Gadermaier G.

Exposure to Indoor Allergens in Diverse Residential Settings and Its Influence on IgE Sensitization in a Geographically Confined Austrian Cohort. PLoS One. Jan 3;12(1):e

Stemeseder T, Klinglmayr E, Moser S, Lueftenegger L, Lang R, Himly M, Oostingh G, Zumbach J, Bathke A, Hawranek T, Gadermaier G. Cross-sectional study on allergic sensitization of Austrian adolescents using molecule-based IgE profiling. Allergy. May;72(5)

Steiner M, Hawranek T, Schneider M, Ferreira F, Horejs-Hoeck J, Harrer A, Himly M. Elevated Toll-Like Receptor-Induced CXCL8 Secretion in Human Blood Basophils from Allergic Donors Is Independent of Toll-Like Receptor Expression Levels.

PLoS One , e /

Silva ES, Pinheiro CS, Quintella CM, Ferreira F, LG CP, Alcantara-Neves NM. Advances in patent applications related to allergen immunotherapy. Expert Opin Ther Pat , /

Moraes AH, Asam C, Batista A, Almeida FC, Wallner M, Ferreira F, Valente AP. 1H, 13C and 15N resonance assignments and second structure information of Fag s 1: Fagales allergen from Fagus sylvatica. Biomol NMR Assign , /sy

McKenna OE, Asam C, Araujo GR, Roulias A, Goulart LR, Ferreira F. How relevant is panallergen sensitization in the development of allergies?

Pediatr Allergy Immunol , /pai

Matricardi PM, Kleine-Tebbe J, Hoffmann HJ, Valenta R, Hilger C, Hofmaier S, Aalberse RC, Agache I, Asero R, Ballmer-Weber B, Barber D, Beyer K, Biedermann T, Bilo MB, Empty S, Bohle B, Bosshard PP, Breiteneder H, Brough HA, Caraballo L, Caubet JC, Crameri R, Davies JM, Douladiris N, Ebisawa M, PA EI, Fernandez-Rivas M, Ferreira F, Gadermaier G, Glatz M, Hamilton RG, Hawranek T, Hellings P, Hoffmann-Sommergruber K, Jakob T, Jappe U, Jutel M, Kamath SD, Knol EF, Korosec P, Kuehn A, Lack G, Lopata AL, Makela M, Morisset M, Niederberger V, Nowak-Wegrzyn AH, Papadopoulos NG, Pastorello EA, Pauli G, Platts-Mills T, Posa D, Poulsen LK, Raulf M, Sastre J, Scala E, Schmid JM, Schmid-Grendelmeier P, van Hage M, van Ree R, Vieths S, Weber R, Wickman M, Muraro A, Ollert M.

EAACI Molecular Allergology User’s Guide. Pediatr Allergy Immunol , 27 Suppl /pai

Machado Y, Freier R, Scheiblhofer S, Thalhamer T, Mayr M, Briza P, Grutsch S, Ahammer L, Fuchs JE, Wallnoefer HG, Isakovic A, Kohlbauer V, Hinterholzer A, Steiner M, Danzer M, Horejs-Hoeck J, Ferreira F, Liedl KR, Tollinger M, Lackner P, Johnson CM, Brandstetter H, Thalhamer J, Weiss R. Fold stability during endolysosomal acidification is a key factor for allergenicity and immunogenicity of the major birch pollen allergen.

J Allergy Clin Immunol , /

Himly M, Nandy A, Kahlert H, Thilker M, Steiner M, Briza P, Neubauer A, Klysner S, van Ree R, Buchheit KH, Vieths S, Ferreira F. Standardization of allergen products: 2. Detailed characterization of GMP-produced recombinant Phl p as European Pharmacopoeia reference standard. Allergy , /all

Goodman RE, Ebisawa M, Ferreira F, Sampson HA, van Ree R, Vieths S, Baumert JL, Bohle B, Lalithambika S, Wise J, Taylor SL. AllergenOnline: A peer-reviewed, curated allergen database to assess novel food proteins for potential cross-reactivity.

Mol Nutr Food Res , /mnfr

Bacher P, Heinrich F, Stervbo U, Nienen M, Vahldieck M, Iwert C, Vogt K, Kollet J, Babel N, Sawitzki B, Schwarz C, Bereswill S, Heimesaat MM, Heine G, Gadermaier G, Asam C, Assenmacher M, Kniemeyer O, Brakhage AA, Ferreira F, Wallner M, Worm M, Scheffold A. Regulatory T Cell Specificity Directs Tolerance versus Allergy against Aeroantigens in Humans. Cell , e /

Abfalter CM, Schonauer E, Ponnuraj K, Huemer M, Gadermaier G, Regl C, Briza P, Ferreira F, Huber CG, Brandstetter H, Posselt G, Wessler S.

Cloning, Purification and Characterization of the Collagenase ColA Expressed by Bacillus cereus ATCC PLoS One , e /

Pablos I, Wildner S, Asam C, Wallner M, Gadermaier G. Pollen Allergens for Molecular Diagnosis Curr Allergy Asthma Rep. Apr;16(4) doi: /sz. Review.

Himly M, Nandy A, Kahlert H, Thilker M, Steiner M, Briza P, Angela N, Klysner S, van Ree R, Buchheit KH, Vieths S, Ferreira F. Standardization of allergen products: 2.

Detailed characterization of GMP-produced recombinant Phl p as European Pharmacopoeia reference standard. Allergy. Dec doi: /all [Epub ahead of print] IF

Machado Y, Freier R, Scheiblhofer S, Thalhamer T, Mayr M, Briza P, Grutsch S, Ahammer L, Fuchs JE, Wallnoefer HG, Isakovic A, Kohlbauer V, Hinterholzer A, Steiner M, Danzer M, Horejs-Hoeck J, Ferreira F, Liedl KR, Tollinger M, Lackner P, Johnson CM, Brandstetter H, Thalhamer J, Weiss R. Fold stability during endolysosomal acidification is a key factor for allergenicity and immunogenicity of the major birch pollen allergen.

J Allergy Clin Immunol. Nov pii: S(15) doi: / [Epub ahead of print] IF

Wimmer M, Alessandrini F, Gilles S, Candid U, Oeder S, Hauser M, Ring J, Ferreira F, Ernst D, Winkler JB, Schmitt-Kopplin P, Ohnmacht C, Behrendt H, Schmidt-Weber C, Traidl-Hoffmann C, Gutermuth J. Pollen-derived adenosine is a necessary cofactor for ragweed allergy. Allergy , /all

Pichler U, Hauser M, Wolf M, Bernardi ML, Gadermaier G, Weiss R, Ebner C, Yokoi H, Takai T, Didierlaurent A, Rafaiani C, Briza P, Mari A, Behrendt H, Wallner M, Ferreira F. Pectate lyase pollen allergens: sensitization profiles and cross-reactivity pattern.

PLoS One , e /

Oeder, S., Alessandrini, F., Wirz, O.F., Braun, A., Wimmer, M., Candid, U., Hauser, M., Durner, J., Ferreira, F., Ernst, D., Mempel, M., Gilles, S., Buters, J.T.M., Behrendt, H., Traidl-Hoffmann, C., Schmidt-Weber, C., Akdis, M., Gutermuth, J. Pollen-derived non-allergenic substances enhance Th2-induced IgE production in B cells. Allergy (Nov ). doi: /all (epub ahead of print). IF

Wimmer, M., Alessandrini, F., Gilles, S., Candid, U., Oeder, S., Hauser, M., Ring, J., Ferreira, F., Ernst, D., Winkler, J.B., Schmitt-Kopplin, P., Ohnmacht, C., Behrendt, H., Schmidt-Weber, C., Traidl-Hoffmann, C., Gutermuth, J. Pollen-derived adenosine is a necessary co-factor for ragweed allergy.

Allergy (Aug ) doi: /all IF

Moraes AH, Asam C, Batista A, Almeida FC, Wallner M, Ferreira F, ValenteAP. 1H, 13C and 15N resonance assignments and second structure information of Fag s 1: Fagales allergen from Fagus sylvatica. Biomol NMR Assign. Aug IF

Kitzmüller C., Zulehner, N., Roulias, A., Briza, P., Ferreira, F., Faé, I., Fischer, G.F., Bohle, B. Correlation of sensitization capacity and T-cell recognition within the Bet v 1 family.

J. Allergy Clin. Immunol. (Jul ) doi: / IF

Asam C, Hofer H, Wolf M, Aglas L, Wallner M. Tree pollen allergens-an update from a molecular perspective. Allergy. Jul doi: /all IF

Pichler, U., Hauser, M., Wolf, M., Bernardi, M.L., Gadermaier, G., Weiss, R., Ebner, C., Yokoi, H., Takai, T., Didierlaurent, D., Rafaiani, C., Briza, P., Mari, A., Behrendt, H., Wallner, M., Ferreira, F. Pectate lyase allergens: sensitization profiles and cross-reactivity pattern. Plos One (May ) 10(5): e doi: / IF

Laimer J, Hofer H, Fritz M, Wegenkittl S, Lackner P. MAESTRO—multi agent stability prediction upon point mutations.

BMC Bioinformatics. Apr 16; doi: /s IF

Dall E, Fegg JC, Briza P, Brandstetter H. Structure and mechanism of an aspartimide-dependent peptide ligase in human legumain. Angew Chem Int Ed Engl. Mar 2;54(10) doi: /anie IF

Kofler, S., Ackaert, C., Samonig, M., Asam, C., Briza, P., Horejs-Hoeck, J., Cabrele, C., Ferreira, F., Duschl, A., Huber, C., Brandstetter, H. Stabilization of the dimerich birch pollen allergen Bet v 1 impacts its immunological properties.

J. Biol. Chem. () , doi: /jbc.M

Radauer, C., Nandy, A., Ferreira, F., Goodman, R.E., Larsen, J.N., Lidholm, J., Pomes, A., Raulf-Heimsoth, M., Rozynek, P., Thomas, W.R., Breiteneder, H. Update of the WHO/IUIS Allergen Nomenclarutre Database based on analysis of allergen sequences. Allergy () doi:/all

Gadermaier, G., Eichhorn, S., Vejvar, E. Weilnböck, L., Lang, R., Briza, P., Huber, C.G., Ferreira, F., Hawranek, T. Plantago lanceolata: an significant trigger of summer pollinosis with limited IgE cross-reactivity.

J. Allergy Clin. Immunol. () doi: /

Asam, C., Batista, A.L., Moraes, A.H. de Paula, V.S., Almeida, F.C.L., Aglas, L., Kitzmüller, C., Bohle, B., Ebner, C., Ferreira, F., Wallner, M., Valente, A.P. Bet v 1 – a Trojan horse for little ligands boosting allergic sensitization? Clin Exp Allergy () doi: /cea

Ferreira, F., Wolf, M., Wallner, M. Molecular approach to allergy diagnosis and Med J () doi: /ymj

Grutsch, S., Fuchs, J.F., Fischer, R., Kofler, S., Bibi, M., Asam, C., Wallner, M., Ferreira, F., Brandstetter, H., Liedl, K.R., Tollinger, M.

Ligand binding modulates structural dynamics and compactness of the major birch pollen allergen. Biophys. J. () doi: /

Moraes, A.H., Ackerbauer, D., Kostadinova, M., Bublin, M., de Oliveira, G.A., Ferreira, F., Almeida, F.C., Breiteneder, H., Valente, A.P. Solution and high-pressure NMR studies of the structure, dynamics, and stability of the cross-reactive allergenic cod parvalbumin Gad m 1. Proteins () doi: /prot

Delfi, S., Zwicker, C., Vejvar, E., Kitzmüller, C., Gadermaier, G., Nagl, B., Vrtala, S., Briza, P., Zlabinger, G.J., Jahn-Schmid, B., Ferreira, F., Bohle, B. Glutathione-S-transferase: a minor allergen in birch pollen due to limited release from hydrated pollen.

Plos One () 9(9):e doi: /

Ackaert, C., Kofler, S., Horejs-Höck, J., Zulehner, N., Asam, C., von Grafenstein, S., Fuchs, J.E., Briza, P., Liedl, K.R., Bohle, B., Ferreira, F., Brandstetter, H., Oostingh, G.J., Duschl, A. The impact of nitration on the structure and immunogenicity of the major birch pollen allergen Bet v Plos One () e doi: /

Roulias, A., Pichler, U., Hauser, M., Himly, M., Hofer, H., Lackner, P., Ebner, C., Briza, P., Bohle, B., Egger, M., Wallner, M., Ferreira, F. Differences in the intrinsic immunogenicity and allergenicity of Bet v 1 and related food allergens revealed by site-directed mutagenesis. Feb;69(2) Epub Nov doi: /all

Pichler, U., Hauser, M., Hofer, H., Himly, M., Hoflehner, E., Steiner, M., Mutschlechner, S., Hufnagl, K., Ebner, C., Mari, A., Briza, P., Bohle, B., Wiedermann, U., Ferreira, F., Wallner, M.

Allergen hybrids – next generation vaccines for Fagales pollen immunotherapy. Clin Exp Allergy. Mar;44(3) doi: /cea

Hofbauer SW, Krenn PW, Ganghammer S, Asslaber D, Pichler U, Oberascher K, Henschler R, Wallner M, Kerschbaum H, Greil R, Hartmann TN. Tiam1/Rac1 signals contribute to the proliferation and chemoresistance, but not motility, of chronic lymphocytic leukemia cells. Blood. Apr 3;(14) doi: /blood

Deressa T, Stoecklinger A, Wallner M, Himly M, Kofler S, Hainz K, Brandstetter H, Thalhamer J, Hammerl P. Structural Integrity of the Antigen Is a Determinant for the Induction of T-Helper Type-1 Immunity in Mice by Gene Gun Vaccines against Beta-Galactosidase.

PLoS One. Jul 15;9(7):e doi: /

Gadermaier G. Non-specific lipid transfer proteins: a protein family in search of an allergenic pattern. Int Arch Allergy Immunol. ;(3) doi: /

Reinmuth-Selzle K, Ackaert C, Kampf CJ, Samonig M, Shiraiwa M, Kofler S, Yang H, Gadermaier G, Brandstetter H, Huber CG, Duschl A, Oostingh GJ, Pöschl U. Nitration of the birch pollen allergen Bet v efficiency and site-selectivity of liquid and gaseous nitrating agents.J Proteome Res.

Mar 7;13(3) doi: /prh.

Schülke S, Wolfheimer S, Gadermaier G, Wangorsch A, Siebeneicher S, Briza P, Spreitzer I, Schiller D, Loeschner B, Uematsu S, Ryffel B, Akira S, Waibler Z, Vieths S, Toda M, Scheurer S. Prevention of intestinal allergy in mice by rflaA:Ova is associated with enforced antigen processing and TLR5-dependent IL secretion by mDC. PLoS One. Feb 7;9(2):e doi: /

Heilmann M, Wellner A, Gadermaier G, Ilchmann A, Briza P, Krause M, Nagai R, Burgdorf S, Scheurer S, Vieths S, Henle T, Toda M. Ovalbumin modified with pyrraline, a Maillard reaction product, shows enhanced T-cell immunogenicity.

J Biol Chem. Mar 14;(11) doi: /jbc.M

Zuidmeer-Jongejan L, Fernández-Rivas M, Winter MG, Akkerdaas JH, Summers C, Lebens A, Knulst AC, Schilte P, Briza P, Gadermaier G, van Ree R. Oil body-associated hazelnut allergens including oleosins are underrepresented in diagnostic extracts but associated with severe symptoms. Clin Transl Allergy. Feb 2;4(1) doi: /

Stemeseder T, Hemmer W, Hawranek T, Gadermaier G. Marker allergens of weed pollen — basic considerations and diagnostic benefits in the clinical routine: Part 16 of the Series Molecular Allergology. Allergo J Int. ;23(8) Epub Dec Review.

Wallner M, Pichler U, Ferreira F.

Recombinant allergens for pollen immunotherapy. Immunotherapy. Dec;5(12) doi: /imt

Roulias A, Pichler U, Hauser M, Himly M, Hofer H, Lackner P, Ebner C, Briza P, Bohle B, Egger M, Wallner M, Ferreira F. Differences in the intrinsic immunogenicity and allergenicity of Bet v 1 and related food allergens revealed by site-directed mutagenesis. Allergy. Feb;69(2) doi: /all Epub Nov

Acevedo N, Mohr J, Zakzuk J, Samonig M, Briza P, Erler A, Pomés A, Huber CG, Ferreira F, Caraballo L.

Proteomic and immunochemical characterization of glutathione transferase as a new allergen of the nematode Ascaris lumbricoides. PLoS One. Nov 4;8(11):e doi: / eCollection

Pichler U, Asam C, Weiss R, Isakovic A, Hauser M, Briza P, Ferreira F, Wallner M. The fold variant BM4 is beneficial in a therapeutic Bet v 1 mouse model. Biomed Res Int. ; doi: // Epub Sep

Vejvar E, Himly M, Briza P, Eichhorn S, Ebner C, Hemmer W, Ferreira F, Gadermaier G. Allergenic relevance of nonspecific lipid transfer proteins 2: Identification and characterization of Api g 6 from celery tuber as representative of a novel IgE-binding protein family. Mol Nutr Food Res.

Nov;57(11) doi: /mnfr Epub Aug 5.

Gadermaier G, Hauser M, Ferreira F. Allergens of weed pollen: An overview on recombinant and natural molecules. Methods. Mar 1;66(1) doi: / Epub Jun Review.

Santos KS, Gadermaier G, Vejvar E, Arcuri HA, Galvão CE, Yang AC, Resende VM, Martins Cde O, Himly M, Mari A, Liso M, Pomponi D, Breiteneder H, Wagner S, Kalil J, Ferreira F, Castro FF. Novel allergens from ancient foods: Man e 5 from manioc (Manihot esculenta Crantz) cross reacts with Hev b 5 from latex.

Mol Nutr Food Res. Jun;57(6) doi: /mnfr Epub Mar

Schulten V, Greenbaum JA, Hauser M, McKinney DM, Sidney J, Kolla R, Lindestam Arlehamn CS, Oseroff C, Alam R, Broide DH, Ferreira F, Grey HM, Sette A, Peters B. Previously undescribed grass pollen antigens are the major inducers of T helper 2 cytokine-producing T cells in allergic individuals. Proc Natl Acad Sci U S A. Feb 26;(9) doi: /pnas Epub Feb Erratum in: Proc Natl Acad Sci U S A.

Mar 26;(13) Ferreira-Briza, Fatima [corrected to Ferreira, Fatima]. Proc Natl Acad Sci U S A.

What is ragweed allergies

May 21;(21)

Gao ZS, Yang ZW, Wu SD, Wang HY, Liu ML, Mao WL, Wang J, Gadermaier G, Ferreira F, Zheng M, van Ree R. Peach allergy in China: a dominant role for mugwort pollen lipid transfer protein as a primary sensitizer. J Allergy Clin Immunol. Jan;(1)e doi: / Epub Aug No abstract available.

Kanter U, Heller W, Durner J, Winkler JB, Engel M, Behrendt H, Holzinger A, Braun P, Hauser M, Ferreira F, Mayer K, Pfeifer M, Ernst D. Molecular and immunological characterization of ragweed (Ambrosia artemisiifolia L.) pollen after exposure of the plants to elevated ozone over a whole growing season.

PLoS One. Apr 18;8(4):e doi: / Print

Weinberger EE, Himly M, Myschik J, Hauser M, Altmann F, Isakovic A, Scheiblhofer S, Thalhamer J, Weiss R. Generation of hypoallergenic neoglycoconjugates for dendritic cell targeted vaccination: a novel tool for specific immunotherapy. J Control Release. Jan 28;(2) doi: /l Epub Nov

Arshad SH, Dharmage SC, Ferreira F, Fixman ED, Gadermaier G, Hauser M, Sampson AP, Teran LM, Wallner M, Wardlaw AJ. Developments in the field of allergy in through the eyes of Clinical and Experimental Allergy.

Clin Exp Allergy. Dec;42(12) doi: /cea Review.

Kitzmüller C, Wallner M, Deifl S, Mutschlechner S, Walterskirchen C, Zlabinger GJ, Ferreira F, Bohle B. A hypoallergenic variant of the major birch pollen allergen shows distinct characteristics in antigen processing and T-cell activation. Allergy. Nov;67(11) doi: /all Epub Sep

Golias J, Schwarzer M, Wallner M, Kverka M, Kozakova H, Srutkova D, Klimesova K, Sotkovsky P, Palova-Jelinkova L, Ferreira F, Tuckova L. Heat-induced structural changes affect OVA-antigen processing and reduce allergic response in mouse model of food allergy.

PLoS One. ;7(5):e doi: / Epub May Erratum in: PLoS One. ;7(8). doi: /annotation/dc-aadd

Karle AC, Oostingh GJ, Mutschlechner S, Ferreira F, Lackner P, Bohle B, Fischer GF, Vogt AB, Duschl A. Nitration of the pollen allergen bet v enhances the presentation of bet v 1-derived peptides by HLA-DR on human dendritic cells. PLoS One. ;7(2):e doi: / Epub Feb

Filep S, Tsay A, Vailes LD, Gadermaier G, Ferreira F, Matsui E, King EM, Chapman MD. Specific allergen concentration of WHO and FDA reference preparations measured using a multiple allergen standard.

J Allergy Clin Immunol. May;(5) doi: / Epub Jan No abstract available.

Jahn-Schmid B, Hauser M, Wopfner N, Briza P, Berger UE, Asero R, Ebner C, Ferreira F, Bohle B. Humoral and cellular cross-reactivity between Amb a 1, the major ragweed pollen allergen, and its mugwort homolog Art v 6. J Immunol. Feb 1;(3) doi: /jimmunol Epub Dec

Siegert M, Pertl-Obermeyer H, Gadermaier G, Ferreira F, Obermeyer G. Expression of the major mugwort pollen allergen Art v 1 in tobacco plants and cell cultures: problems and perspectives for allergen production in plants. Plant Cell Rep. Mar;31(3) doi: /s Epub Dec

Filep S, Tsay A, Vailes L, Gadermaier G, Ferreira F, Matsui E, King EM, Chapman MD. A multi-allergen standard for the calibration of immunoassays: CREATE principles applied to eight purified allergens.

Allergy. Feb;67(2) doi: /jx. Epub Nov

Kofler S, Asam C, Eckhard U, Wallner M, Ferreira F, Brandstetter H. Crystallographically mapped ligand binding differs in high and low IgE binding isoforms of birch pollen allergen Bet v 1. J Mol Biol. Sep 7;(1) doi: / Epub May

Zaborsky N, Brunner M, Wallner M, Himly M, Karl T, Schwarzenbacher R, Ferreira F, Achatz G. Response to Detection and analysis of unusual features in the structural model and structure-factor data of a birch pollen allergen. Acta Crystallogr Sect F Struct Biol Cryst Commun. Apr 1;68(Pt 4) doi: /S Epub Mar

Hoy B, Geppert T, Boehm M, Reisen F, Plattner P, Gadermaier G, Sewald N, Ferreira F, Briza P, Schneider G, Backert S, Wessler S.

Distinct roles of secreted HtrA proteases from gram-negative pathogens in cleaving the junctional protein and tumor suppressor E-cadherin. J Biol Chem. Mar 23;(13) doi: /jbc.C Epub Feb

Hauser M, Asam C, Himly M, Palazzo P, Voltolini S, Montanari C, Briza P, Bernardi ML, Mari A, Ferreira F, Wallner M.Bet v 1-like pollen allergens of multiple Fagales species can sensitize atopic individuals.Clin Exp Allergy.

Dec;41(12)

Gadermaier G, Hauser M, Egger M,Ferrara R, Briza P, Santos KS, Zennaro D, Girbl T, Zuidmeer-Jongejan L, Mari A, Ferreira F. Sensitization prevalence, antibody cross-reactivity and immunogenic peptide profile of Api g 2, the non-specific lipid transfer protein 1 of celery.PLoS One. ;6(8):e Epub Aug


Santos KS, Galvao CE, Gadermaier G, Resende VM, de Oliveira Martins C, Misumi DS, Yang AC, Ferreira F, Palma MS, Kalil J, Castro FF.
Allergic reactions to manioc (Manihot esculenta Crantz): identification of novel allergens with potential involvement in latex-fruit syndrome.
J Allergy Clin Immunol.

Dec;(6)

Pasqualini S, Tedeschini E, Frenguelli G, Wopfner N, Ferreira F, D´Amato G, Ederli L. Ozone affects pollen viability and NAD(P)H oxidase release from Ambrosia artemisiifolia pollen.
Environ Pollut. Oct;(10)

Egger M, Alessandri C, Wallner M, Briza P, Zennaro D, Mari A, Ferreira F, Gadermaier G. Is aboriginal food less allergenic? Comparing IgE-reactivity of eggs from modern and ancient chicken breeds in a cohort of allergic children.
PLoS One. Apr 28;6(4):e

Gadermaier G, Egger M, Girbl T, Erler A, Harrer A, Vejvar E, Liso M, Richter K, Zuidmeer L, Mari A, Ferreira F.

Molecular characterization of Api g 2, a novel allergenic member of the lipid-transfer protein 1 family from celery stalks.
Mol Nutr Food Res. Apr;55(4)

Wallner M, Hauser M, Himly M, Zaborsky N, Mutschlechner S, Harrer A, Asam C, Pichler U, van Ree R, Briza P, Thalhamer J, Bohle B, Achatz G, Ferreira F. Reshaping the Bet v 1 fold modulates T(H) polarization.
J Allergy Clin Immunol. Jun;(6)e9.

Erler A, Hawranek T, Krückemeier L, Asam C, Egger M, Ferreira F, Briza P. Proteomic profiling of birch (Betula verrucosa) pollen extracts from diverse origins.
Proteomics.

Apr;11(8)

Egger M, Jürets A, Wallner M, Briza P, Ruzek S, Hainzl S, Pichler U, Kitzmüller C, Bohle B, Huber CG, Ferreira F. Assessing protein immunogenicity with a dendritic cell line-derived endolysosomal degradome.
PLoS One. Feb 16;6(2):e

Schulten V, Nagl B, Scala E, Bernardi ML, Mari A, Ciardiello MA, Lauer I, Scheurer S, Briza P, Jürets A, Ferreira F, Jahn-Schmid B, Fischer GF, Bohle B. Pru p 3, the nonspecific lipid transfer protein from peach, dominates the immune response to its homolog in hazelnut.

Allergy. Aug;66(8)

D´Avino R, Bernardi ML, Wallner M, Palazzo P, Camardella L, Tuppo L, Alessandri C, Breiteneder H, Ferreira F, Ciardiello MA, Mari A.
Kiwifruit Act d 11 is the first member of the ripening-related protein family identified as an allergen. Allergy. Jul;66(7)

Aiub CA, Gadermaier G, Silva IO, Felzenszwalb I, Pinto LF, Ferreira F, Eckl P.N-nitrosodiethylamine genotoxicity evaluation: a cytochrome P induction study in rat hepatocytes. Genet Mol Res. Oct 5;10(4)

Aiub CA, Gadermaier G, Oliveira I, Felzenszwalb I, Ferreira F, Ribeiro Pinto LF, Eckl P.N-Nitrosodiethylamine genotoxicity in primary rat hepatocytes: effects of cytochrome P induction by phenobarbital.

Toxicol Lett. Oct 10;(2)

Gadermaier G, Egger M, Girbl T, Erler A, Harrer A, Vejvar E, Liso M, Richter K, Zuidmeer L, Mari A, Ferreira F. Molecular characterization of Api g 2, a novel allergenic member of the lipid-transfer protein 1 family from celery stalks.
Mol Nutr Food Res. Dec

Zaborsky N, Brunner M, Wallner M, Himly M, Karl T, Schwarzenbacher R, Ferreira F, Achatz G. Antigen aggregation decides the fate of the allergic immune response.

J Immunol. Jan 15;(2)

Harrer A, Lang R, Grims R, Braitsch M, Hawranek T, Aberer W, Vogel L, Schmid W, Ferreira F, Himly M. Diclofenac hypersensitivity: antibody responses to the parent drug and relevant metabolites. PLoS One. Oct 28;5(10):e

Acevedo N, Erler A, Briza P, Puccio F, Ferreira F, Caraballo L.
Allergenicity of Ascaris lumbricoides tropomyosin and IgE sensitization among asthmatic patients in a tropical environment. Int Arch Allergy Immunol. ;(3) Epub Sep

Weiss R, Scheiblhofer S, Roesler E, Ferreira F, Thalhamer J.
Prophylactic mRNA vaccination against allergy. Curr Opin Allergy Clin Immunol.

Dec;10(6)

Razzera G, Gadermaier G, de Paula V, Almeida MS, Egger M, Jahn-Schmid B, Almeida FC, Ferreira F, Valente AP.
Mapping the interactions between a major pollen allergen and human IgE antibodies. Structure. Aug 11;18(8)

Jahn-Schmid B, Wopfner N, Hubinger G, Asero R, Ebner C, Ferreira F, Bohle B. The T-cell response to Amb a 1 is characterized by 3 dominant epitopes and multiple MHC restriction elements. J Allergy Clin Immunol. Nov;(5), e

Egger M, Hauser M, Mari A, Ferreira F, Gadermaier G.
The role of lipid transfer proteins in allergic diseases.

What is ragweed allergies

Curr Allergy Asthma Rep. Sep;10(5) Review.

Léonard R, Wopfner N, Pabst M, Stadlmann J, Petersen BO, Duus JØ, Himly M, Radauer C, Gadermaier G, Razzazi-Fazeli E, Ferreira F, Altmann F. A new allergen from ragweed (Ambrosia artemisiifolia) with homology to art v 1 from mugwort.Biol Chem. Aug 27;(35)


Magler I, Nüss D, Hauser M, Ferreira F, Brandstetter H.
Molecular metamorphosis in polcalcin allergens by EF-hand rearrangements and domain swapping. FEBS Jun;(12)

Thalhamer T, Dobias H, Stepanoska T, Pröll M, Stutz H, Dissertori O, Lackner P, Ferreira F, Wallner M, Thalhamer J, Hartl A. Designing hypoallergenic derivatives for allergy treatment by means of in silico mutation and screening.Allergy Clin Immunol.

Apr;(4)e

Hauser M, Roulias A, Ferreira F, Egger M. Panallergens and their impact on the allergic patient. Allergy Asthma Clin Immunol. Jan 18;6(1)

Valenta R, Ferreira F, Focke-Tejkl M, Linhart B, Niederberger V, Swoboda I, Vrtala S.
From allergen genes to allergy vaccines. Annu Rev Immunol. Mar; Review.

Mutschlechner S, Egger M, Briza P, Wallner M, Lackner P, Karle A, Vogt AB, Fischer GF, Bohle B, Ferreira F.Naturally processed T cell-activating peptides of the major birch pollen allergen. J Allergy Clin Immunol. Mar;(3), ee2.

Gadermaier G, Jahn-Schmid B, Vogel L, Egger M, Himly M, Briza P, Ebner C, Vieths S, Bohle B, Ferreira F.Targeting the cysteine-stabilized fold of Art v 1 for immunotherapy of Artemisia pollen allergy.
Mol Immunol.

Mar;47(6)

Smole U, Balazs N, Hoffmann-Sommergruber K, Radauer C, Hafner C, Wallner M, Ferreira F, Grössinger R, de Jong EC, Wagner S, Breiteneder H.Differential T-cell responses and allergen uptake after exposure of dendritic cells to the birch pollen allergens Bet v , Bet v and Bet v
Immunobiology. Nov;(11)

Harrer A, Egger M, Gadermaier G, Erler A, Hauser M, Ferreira F, Himly M.Characterization of plant food allergens: an overview on physicochemical and immunological techniques.
Mol Nutr Food Res. Jan;54(1) Review.

Roesler E, Weiss R, Weinberger EE, Fruehwirth A, Stoecklinger A, Mostböck S, Ferreira F, Thalhamer J, Scheiblhofer S.

What is ragweed allergies

Immunize and disappear-safety-optimized mRNA vaccination with a panel of 29 allergens. J Allergy Clin Immunol. Nov;(5)e

Egger M, Hauser M, Himly M, Wopfner N, Wallner M, Ferreira F. Development of recombinant allergens for diagnosis and therapy. Front Biosci (Elite Ed). Jun 1;

Gadermaier G, Harrer A, Girbl T, Palazzo P, Himly M, Vogel L, Briza P, Mari A, Ferreira F. Isoform identification and characterization of Art v 3, the lipid-transfer protein of mugwort pollen.

Mol Immunol. Jun;46(10)

Gruber P, Gadermaier G, Bauer R, Weiss R, Wagner S, Leonard R, Breiteneder H, Ebner C, Ferreira F, Egger M. Role of the polypeptide backbone and post-translational modifications in cross-reactivity of Art v 1, the major mugwort pollen allergen. Biol Chem. May-Jun;()

Wopfner N, Jahn-Schmid B, Schmidt G, Christ T, Hubinger G, Briza P, Bohle B, Vogel L, Ebner C, Asero R, Ferreira F, Schwarzenbacher R. The alpha and beta subchain of Amb a 1, the major ragweed-pollen allergen show divergent reactivity at the IgE and T-cell level. Mol Immunol. Mar 5.

Himly M, Nony E, Chabre H, Van Overtvelt L, Neubauer A, van Ree R, Buchheit KH, Vieths S, Moingeon P, Ferreira F.

Standardization of allergen products: 1. Detailed characterization of GMP-produced recombinant Bet v as biological reference preparation. Allergy. Jan

Wallner M, Erler A, Hauser M, Klinglmayr E, Gadermaier G, Vogel L, Mari A, Bohle B, Briza P, Ferreira F. Immunologic characterization of isoforms of Car b 1 and Que a 1, the major hornbeam and oak pollen allergens.
Allergy. Mar;64(3) Epub Jan

Klinglmayr E, Hauser M, Zimmermann F, Dissertori O, Lackner P, Wopfner N, Ferreira F, Wallner M.

Identification of B-cell epitopes of Bet v 1 involved in cross-reactivity with food allergens. Array-based profiling of ragweed and mugwort pollen allergens. Allergy. Jan 9.

Dedic A, Gadermaier G, Vogel L, Ebner C, Vieths S, Ferreira F, Egger M. Immune recognition of novel isoforms and domains of the mugwort pollen major allergen Art v 1. Array-based profiling of ragweed and mugwort pollen allergens.
Mol Immunol. Jan;46(3) Epub Dec 2.

Gadermaier G, Wopfner N, Wallner M, Egger M, Didierlaurent A, Regl G, Aberger F, Lang R, Ferreira F, Hawranek T.

Array-based profiling of ragweed and mugwort pollen allergens. Allergy. Nov;63(11)

Mohapatra SS, San-Juan-Vergara H, Wopfner N, Ferreira F. Experimental forms of allergen immunotherapy with modified allergens and adjuvants. Clin Allergy Immunol. ; Review.

Chapman MD, Ferreira F, Villalba M, Cromwell O, Bryan D, Becker WM, Fernández-Rivas M, Durham S, Vieths S, van Ree R. CREATE consortium. The European Union CREATE project: a model for international standardization of allergy diagnostics and vaccines. J Allergy Clin Immunol. Nov;(5)e2.

Jahn-Schmid B, Sirven P, Leb V, Pickl WF, Fischer GF, Gadermaier G, Egger M, Ebner C, Ferreira F, Maillére B, Bohle B. Characterization of HLA class II/peptide-TCR interactions of the immunodominant T cell epitope in Art v 1, the major mugwort pollen allergen.J Immunol.

Sep 1;(5)

Wopfner N, Gruber P, Wallner M, Briza P, Ebner C, Mari A, Richter K, Vogel L, Ferreira F.
Molecular and immunological characterization of novel weed pollen pan-allergens. Allergy. Jul;63(7)

van Ree R, Chapman MD, Ferreira F, Vieths S, Bryan D, Cromwell O, Villalba M, Durham SR, Becker WM, Aalbers M, André C, Barber D, Cistero Bahima A, Custovic A, Didierlaurent A, Dolman C, Dorpema JW, Di Felice G, Eberhardt F, Fernandez Caldas E, Fernandez Rivas M, Fiebig H, Focke M, Fötisch K, Gadermaier G, Das RG, Gonzalez Mancebo E, Himly M, Kinaciyan T, Knulst AC, Kroon AM, Lepp U, Marco FM, Mari A, Moingeon P, Monsalve R, Neubauer A, Notten S, Ooievaar-de Heer P, Pauli G, Pini C, Purohit A, Quiralte J, Rak S, Raulf-Heimsoth M, San Miguel Moncin MM, Simpson B, Tsay A, Vailes L, Wallner M, Weber B.The CREATE project: development of certified reference materials for allergenic products and validation of methods for their quantification.

Allergy. Mar;63(3) Review.

Wopfner N, Bauer R, Thalhamer J, Ferreira F, Chapman M.Immunologic analysis of monoclonal and immunoglobulin E antibody epitopes on natural and recombinant Amb a 1.Clin Exp Allergy. Jan;38(1)

Oberhuber C, Ma Y, Wopfner N, Gadermaier G, Dedic A, Niggemann B, Maderegger B, Gruber P, Ferreira F, Scheiner O, Hoffmann-Sommergruber K.Prevalence of IgE-binding to Art v 1, Art v 4 and Amb a 1 in mugwort-allergic patients.Int Arch Allergy Immunol.

;(2)

Westritschnig K, Linhart B, Focke-Tejkl M, Pavkov T, Keller W, Ball T, Mari A, Hartl A, Stöcklinger A, Scheiblhofer S, Thalhamer J, Ferreira F, Vieths S, Vogel L, Böhm A, Valent P, Valenta R. A hypoallergenic vaccine obtained by tail-to-head restructuring of timothy grass pollen profilin, Phl p 12, for the treatment of cross-sensitization to profilin.J Immunol. Dec 1;(11)

Wallner M, Stöcklinger A, Thalhamer T, Bohle B, Vogel L, Briza P, Breiteneder H, Vieths S, Hartl A, Mari A, Ebner C, Lackner P, Hammerl P, Thalhamer J, Ferreira F.
Allergy multivaccines created by DNA shuffling of tree pollen allergens.J Allergy Clin Immunol.

Aug;(2)

Stoecklinger A, Grieshuber I, Scheiblhofer S, Weiss R, Ritter U, Kissenpfennig A, Malissen B, Romani N, Koch F, Ferreira F, Thalhamer J, Hammerl P.
Epidermal langerhans cells are dispensable for humoral and cell-mediated immunity elicited by gene gun immunization.
J Immunol. Jul 15;(2)

Wallner M, Briza P, Thalhamer J, Ferreira F.Specific immunotherapy in pollen allergy.Curr Opin Mol Ther.

Apr;9(2) Review.

Wopfner N, Dissertori O, Ferreira F, Lackner P.
Calcium-binding proteins and their role in allergic diseases.Immunol Allergy Clin North Am. Feb;27(1) Review.

Chapman MD, Pomés A, Breiteneder H, Ferreira F.
Nomenclature and structural biology of allergens.J Allergy Clin Immunol. Feb;(2) Review.

Wild C, Wallner M, Hufnagl K, Fuchs H, Hoffmann-Sommergruber K, Breiteneder H, Scheiner O, Ferreira F, Wiedermann U. A recombinant allergen chimer as novel mucosal vaccine candidate for prevention of multi-sensitivities.
Allergy. Jan;62(1)

Mutschlechner S, Ferreira F. Engineering allergens.

Eur Ann Allergy Clin Immunol. Sep;38(7) Review.

Zuidmeer L, van Leeuwen WA, Kleine Budde I, Breiteneder H, Ma Y, Mills C, Sancho AI, Meulenbroek EJ, van de Weg E, Gilissen L, Ferreira F, Hoffmann-Sommergruber K, van Ree R. Allergenicity assessment of apple cultivars: hurdles in quantifying labile fruit allergens.Int Arch Allergy Immunol. ;(3)

Ma Y, Zuidmeer L, Bohle B, Bolhaar ST, Gadermaier G, Gonzalez-Mancebo E, Fernandez-Rivas M, Knulst AC, Himly M, Asero R, Ebner C, van Ree R, Ferreira F, Breiteneder H, Hoffmann-Sommergruber K.Characterization of recombinant Mal d 4 and its application for component-resolved diagnosis of apple allergy.Clin Exp Allergy.

Aug;36(8)

Radauer, C., Willerroider, M., Fuchs, H., Hoffmann-Sommergruber, K., Thalhamer, J., Ferreira, F., Scheiner, O., Breiteneder, H. Cross-reactive and species-specific immunoglobuliin E epitopes of plant profilins: an experimental and structure-based analysis.Clin Exp Allergy. Jul;36(7)

Bauer R, Scheiblhofer S, Kern K, Gruber C, Stepanoska T, Thalhamer T, Hauser-Kronberger C, Alinger B, Zoegg T, Gabler M, Ferreira F, Hartl A, Thalhamer J, Weiss R.Generation of hypoallergenic DNA vaccines by forced ubiquitination: preventive and therapeutic effects in a mouse model of allergy.
J Allergy Clin Immunol.

Jul;(1)

Scheiblhofer S, Gabler M, Leitner WW, Bauer R, Zoegg T, Ferreira F, Thalhamer J, Weiss R.Inhibition of type I allergic responses with nanogram doses of replicon-based DNA vaccines.Allergy. Jul;61(7)

Asero R, Wopfner N, Gruber P, Gadermaier G, Ferreira F.Artemisia and Ambrosia hypersensitivity: co-sensitization or co-recognition?Clin Exp Allergy. May;36(5)

Ferreira F, Briza P, Inführ D, Schmidt G, Wallner M, Wopfner N, Thalhamer J, Achatz G.Modified recombinant allergens for safer immunotherapy.Inflamm Allergy Drug Targets.

Jan;5(1) Review.

Jahn-Schmid, B., Fischer, G., Bohle, B., Fae, I., Gadermaier, G., Dedic, A., Ferreira, F., Ebner, C. Antigen presentation of the immunodominant T cell epitope of the major mugwort pollen allergen, Art v 1, is associated with the expression of HLA-DRB1*J. Allergy Clin. Immunol. ,

Leonard, R., Petersen, B.O., Himly, M., Kaar, W., Wopfner, N., Kolarich, D., van Ree, R., Ebner, C., Duus, J.Ø., Ferreira, F., Altmann, F. Two novel types of O-glycans on the mugwort pollen allergen Art v 1 and their role in antibody binding.
J.

Biol. Chem. ,

Hebenstreit, D., Ferreira, F. Structural changes in calcium-binding allergens: use of circular dichroism to study binding characteristics.Allergy ,

Bolhaar, S.T.H.P., Zuidmeer, L., Ma, Y., Ferreira, F., Bruijnzeel-Koomen, C.A.F.M., Hoffmann-Sommergruber, van Ree, R., Knulst, A.C. A mutant of the major apple allergen, Mal d 1 demonstrating hypo-allergenicity in target organ by DBPCFC.Clin. Exp. Allergy ,

Obermeyer, G., Ferreira, F.

Can we predict or avoid the allergenic potential of genetically modified organisms?Int. Arch. Allergy Immunol. ,

Wopfner, N., Gadermaier, G., Egger, M., Asero, R., Ebner, C., Jahn-Schmidt, B., Ferreira, F.The spectrum of allergens in ragweed and mugwort pollen.
Int. Arch. Allergy Immunol. ,

Hartl., A., Hochreiter, R., Stepanoska, T., Ferreira, F., Thalhamer, J. Characterization of the protective and therapeutic efficiency of a DNA vaccine encoding the major birch pollen allergen Bet v 1a.Allergy ,

Ferreira, F., Hawranek, T., Gruber, P., Wopfner, N., Mari, A.

Allergic cross-reactivity: from gene to the clinic.Allergy ,

Wallner, M., Gruber, P., Radauer, C., Maderegger, B., Susani, M., Hoffman-Sommergruber, K., Ferreira, F. Lab scale and medium production of recombinant allergens in Escherichia coli.Methods ,

Obermeyer, G., Gehwolf, R., Sebesta, W., Hamilton, N., Gadermaier, G., Ferreira, F., Commandeur, U., Fisher, R., Bentrup, F.W. Over-expression and production of plant allergens by molecular farming strategies.Methods ,

Ferreira, F., Wallner, M., Thalhamer, J.
Costumized antigens and immunomodulations for desensitizing allergic patients.Adv.

Immunol. ,

Neudecker, P., Nerkamp, J., Eisenmann, A., Nourse, A., Lauber, T., Schweimer, K., Lehmann, K., Ferreira, F., Rösch, P. Solution structure, dynamics, and hydrodynamics of the calcium-bound cross-reactive birch pollen allergen Bet v 4 reveal a canonical monomeric two EF-hand assembly with a regulatory function.J. Mol. Biol. ,

Gadermaier, G., Dedic, A., Obermeyer, G., Candid, S., Himly, M., Ferreira, F.Biology of weed pollen allergens.Current Allergy and Asthma Rep.

,

Markovic-Housley, Z., Degano, M., Lamba, D., von Roepenack-Lahaye, E., Clemens, S., Susani, M., Ferreira, F., Scheiner, O., Breiteneder, H. Crystal structure of a hypoallergenic isoform of the major birch pollen allergen Bet v 1 and its likely biological function as a plant steroid carrier.J. Mol. Biol. ,

Himly, M., Jahn-Schmid, B., Pittertschatscher, K., Bohle, B., Grubmayr, K., Ferreira, F., Ebner, H., Ebner, C. IgE-mediated immediate-type hypersensitivity to the pyrazolone drug propyphenazone.J. Allergy Clin. Immunol. ,

Schmid-Grendelmeier, P., Holzmann,D., Himly, M., Weichel, M., Tresch, S., Ruckert, B., Menz, G., Ferreira, F., Blaser, K., Wüthrich, B., Crameri, R. Native and recombinant Art v 1 are capable to induce humoral and T cell mediated in vitro and in vivo responses in mugwort allergy.J.

Allergy Clin. Immunol ,

Krebitz, M., Wagner, B., Ferreira, F., Peterbauer, C., Campillo, N., Witty, M., Kolarich, D., Steinkellner, H., Scheiner, O., Breiteneder, H. Plant-based heterologous expression of Mal d 2, a thaumatin-like protein and allergen of apple (Malus domestica), and its characterization as an antifungal-protein.J. Mol. Biol. ,

Hochreiter, R., Stepanoska, T., Ferreira, F., Valenta, R., Vrtala, S., Thalhamer, J., Hartl, A. Prevention of allergen-specific IgE production and suppression of an estabished Th2-type response by immunization with DNA encoding hypoallergenic derivatives of Bet v 1, the major birch pollen allergen.Eur.

J. Immunol. ,

Bauer, R., Himly, M., Dedic, A., Ferreira, F., Josef Thalhamer, J., Hartl, A. Optimization of codon usage is required for effective genetic immunization against Art v 1, the major allergen of mugwort pollen.Allergy ,

Hochreiter, R., Ferreira, F., Thalhamer, J., Hammerl, P. Th1-promoting DNA immunization against allergens modulates the ratio of IgG1/IgG2a but does not affect anaphylactic potential of IgG1 antibodies: no evidence for the synthesis of non-anaphylactic IgG1.J. Allergy Clin. Immunol. ,

Willerroider, M., Fuchs, H., Ballmer-Weber, B., Focke, M., Susani, M., Thalhamer, J., Ferreira, F., Wüthrich, B., Scheiner, O., Breiteneder, H., Hoffmann-Sommergruber, K. Cloning and Molecular and Immunological Characterization of Two New Food Allergens, Lyc e 1 and Cap a 2, Profilins From Bell Pepper (Capsicum annuum) and TomatoInt.

Arch Allergy Immunol. ,

Mari, A., Wallner, M., Ferreira, F. Fagales pollen allergy in a birch-free area: a population survey using Fagales pollen extracts and birch recombinant allergens (rBet v 1, rBet v 2, rBet v 4).Clin. Exp. Allergy ,

Hiller, R., Laffer, S., Harwanegg, C., Huber, M., Schmid, W., Twardosz, A., Becker, W.M., Blaser, K., Breiteneder, H., Chapman, M., Crameri, R., Duchene, M., Ferreira, F., Fiebig., H., et al.

Microarrayed allergen molecules: Diagnostic gatekeepers for allergy treatment.FASEB J. (January 14, ) /fjfje

Weiss, R., Scheiblhofer, S., Freund, J., Ferreira, F., Livey, I., Thalhamer, J. Gene gun bombardment with gold particles displays a specific Th2-promoting signal that over-rules the Th1-inducing effect of immunostimulatory CpG motifs in DNA vaccines.Vaccine ,

Ferreira, F., Wallner, M., Breiteneder, H., Hartl, A., Thalhamer, J., Ebner, C. Genetic engineering of allergens: Future therapeutic products.Int.

Arch. Allergy Immunol. ,

Wopfner, N., Willeroider, M., Hebenstreit, D., van Ree, Ronald, Aalbers, M., Briza, P., Thalhamer, J., Ebner, C., Richter, K., Ferreira, F. Molecular and immunological characterization of profilin from mugwort pollen.Biol. Chem. ,

Himly, M., Jahn-Schmid, B., Dedic, A., Kelemen, P., Wopfner, N., Altmann, F., van Ree, R., Briza, P., Richter, K., Ebner, C., Ferreira, F. (). Art v 1, the major allergen of mugwort pollen is a modular glycoprotein with a defensin-like and a hydroxyproline-rich domain.FASEB J /fjfje,FASEB J ,

Jahn-Schmid, B.

Kelemen, P., Himly, M., Bohle, B., Fischer, G., Ferreira, F., Ebner, C. The T cell response to Art v 1, the major mugwort pollen allergen, is dominated by one epitope.J. Immunol. ,

Geisberger, R., Prlic, M., Achatz-Straussberger, G., Oberndorfer, I., Luger, E., Lamers, M., Crameri, R., Appenzeller, U., Wienands, J., Ferreira, F., Achatz, G.
Phage display based cloning of proteins interacting with the cytoplasmic tail of membrane immunoglobulins.Developmental Immunology 9: ,

Pertl, H., Himly, M., Gehwolf, R., Kriechbaumer, R., Strasser, D., Michalke, W., Richter, K., Ferreira, F., Obermeyer, G.

Molecular and physiological characterisation of a protein from lily pollen grains regulating the activity of the plasma membrane H+ATPase during pollen grain germination and tube growth.
Planta ,

Ferreira F., Himly, M., Hebenstreit D., Dabrowska, M., Vollmann, U., Kraft, D., Obermeyer, G., Richter, K. Isolation and characterization of cDNA clones coding for Mugwort (Artemisia vulgaris) Pollen AllergensInt. Arch. Allergy Immunol., ,

Simon-Nobbe, B., Kodzius, R., Kajava, A., Ferreira, F., Kungl, A., Achatz, G., Crameri, R., Ebner, C., Breitenbach, M.

Structure of an IgE-binding peptide from fungal enolases.Int. Arch. Allergy Immunol., ,

Hochreiter, R., Hartl, A., Freund, J., Valenta, R., Ferreira, F., Thalhamer J. The influence of CpG motifs on a protein or DNA-based Th2 type immune response against major pollen allergens Bet v 1a, Phl p 2 and Escherichia coli-derived ß-galactosidase.Int. Arch. Allergy Immunol.

What is ragweed allergies

,

zurück

Kitzmuller C, Kalser J, Mutschlechner S, Hauser M, Zlabinger GJ, Ferreira F, Bohle B. Fusion proteins of flagellin and the major birch pollen allergen Bet v 1 show enhanced immunogenicity, reduced allergenicity, and intrinsic adjuvanticity. J Allergy Clin Immunol , , doi: /

Pablos I, Eichhorn S, Machado Y, Briza P, Neunkirchner A, Jahn-Schmid B, Wildner S, Soh WT, Ebner C, Park JW, Pickl W, Arora N, Vieths, S, Ferreira F, Gadermaier G.

Distinct epitope structures of defensin-like proteins linked to proline-rich regions give rise to diferrences in their allergenic activity. Allergy , doi: /all

Strasser L, Dang HH, Schwarz H, Asam C, Ferreira F, Horejs-Hoeck J, Huber CG. Unbiased quantitative proteomics reveals a crucial role of the allergen context for the activation of human dendritic cells. Scientific Rep , doi: /s

Wolf M, Aglas L, Twaroch TE, Steiner M, Huber S, Hauser M, Parigiani MA, Hofer H, Ebner C, Bohle B, Briza P, Nubauer A, Stolz F, Wallner M, Ferreira F.

Endolysosomal protease susceptibility of Amb a 1 as a determinant of allergenicity. J Allergy Clin Immunol (epub ahead of print). doi: /

Schülke S, Kuttich K, Wolfheimer S, Duschek N, Wangorsch A, Reuter A, Briza P, Pablos I, Gadermaier G, Ferreira F, Vieths S, Toda M, Scheurer S. Conjugation of wildtype and hypoallergenic mugwort allergen Art v 1 to flagellin induces ILDC and suppresses allergen-specific TH2-responses in vivo. Scientific Rep , doi: /sw

Zulehner N, Nagl B, Briza P, Roulias A, Ballmer-Weber B, Zlabinger GJ, Ferreira F, Bohle B.

Characterization of the T-cell response to Dau c 1, the Bet v 1-homolog in carrot. Allergy , /all

Wolf M, Twaroch TE, Huber S, Reithofer M, Steiner M, Aglas L, Hauser M, Aloisi I, Asam C, Hofer H, Parigiani MA, Ebner C, Bohle B, Briza P, Neubauer A, Stolz F, Jahn-Schmid B, Wallner M, Ferreira F. Amb a 1 isoforms: Unequal siblings with distinct immunological features. Allergy , /all/all

Stemeseder T, Freier R, Wildner S, Fuchs JE, Briza P, Lang R, Batanero E, Lidholm J, Liedl KR, Campo P, Hawranek T, Villalba M, Brandstetter H, Ferreira F, Gadermaier G.

Crystal structure of Pla l 1 reveals both structural similarity and allergenic divergence within the Ole e 1-like protein family. J Allergy Clin Immunol , /

Santos da Silva E, Asam C, Lackner P, Hofer H, Wallner M, Silva Pinheiro C, Alcantara-Neves NM, Ferreira F. Allergens of Blomia tropicalis: An Overview of Recombinant Molecules. Int Arch Allergy Immunol , /

Soh WT, Briza P, Dall E, Asam C, Schubert M, Huber S, Aglas L, Bohle B, Ferreira F, Brandstetter H. Two Distinct Conformations in Bet v 2 Determine Its Proteolytic Resistance to Cathepsin S. Int J Mol Sci. , pii:E doi: /ijms

Sancho AI, Wallner M, Hauser M, Nagl B, Himly M, Asam C, Ebner C, Jahn-Schmid B, Bohle B, Ferreira F. T Cell Epitope-Containing Domains of Ragweed Amb a 1 and Mugwort Art v 6 Modulate Immunologic Responses in Humans and Mice.

PLoS One , e /

Pablos I, Eichhorn S, Briza P, Asam C, Gartner U, Wolf M, Ebner C, Bohle B, Arora N, Vieths S, Ferreira F, Gadermaier G. Proteomic profiling of the weed feverfew, a neglected pollen allergen source. Sci Rep , 7: /sz

McKenna OE, Posselt G, Briza P, Lackner P, Schmitt AO, Gadermaier G, Wessler S, Ferreira F. Multi-Approach Analysis for the Identification of Proteases within Birch Pollen. Int J Mol Sci , /ijms

Hollbacher B, Schmitt AO, Hofer H, Ferreira F, Lackner P. Identification of Proteases and Protease Inhibitors in Allergenic and Non-Allergenic Pollen.

Int J Mol Sci , /ijms

Hofer H, Asam C, Hauser M, Nagl B, Laimer J, Himly M, Briza P, Ebner C, Lang R, Hawranek T, Bohle B, Lackner P, Ferreira F, Wallner M. Tackling Bet v 1 and associated food allergies with a single hybrid protein. J Allergy Clin Immunol , e /

Hirschl S, Ralser C, Asam C, Gangitano A, Huber S, Ebner C, Bohle B, Wolf M, Briza P, Ferreira F, Griesbeck C, Wallner M. Expression and Characterization of Functional Recombinant Bet v in the Chloroplast of Chlamydomonas reinhardtii.

Int Arch Allergy Immunol , /

Ahammer L, Grutsch S, Wallner M, Ferreira F, Tollinger M. NMR resonance assignments of a hypoallergenic isoform of the major birch pollen allergen Bet v 1. Biomol NMR Assign , , doi: /s

Wildner S, Elsässer B, Stemeseder T, Briza P, Soh WT, Villalba M, Lidholm J, Brandstetter H, Gadermaier G. Endolysosomal Degradation of Allergenic Ole e 1-Like Proteins: Analysis of Proteolytic Cleavage Sites Revealing T Cell Epitope-Containing Peptides Int J Mol Sci. Aug 16;18(8). pii: E

Stemeseder T, Klinglmayr E, Moser S, Lang R, Himly M, Oostingh GJ, Zumbach J, Bathke AC, Hawranek T, Gadermaier G. Influence of intrinsic and lifestyle factors on the development of IgE sensitization.

Int Arch Allergy Immunol. ;(2)

Stemeseder T, Schweidler B, Doppler P, Klinglmayr E, Moser S, Lueftenegger L, Himly M, Lang R, Zumbach J, Oostingh GJ, Hawranek T, Bathke AC, Gadermaier G. Exposure to Indoor Allergens in Diverse Residential Settings and Its Influence on IgE Sensitization in a Geographically Confined Austrian Cohort. PLoS One. Jan 3;12(1):e

Stemeseder T, Klinglmayr E, Moser S, Lueftenegger L, Lang R, Himly M, Oostingh G, Zumbach J, Bathke A, Hawranek T, Gadermaier G. Cross-sectional study on allergic sensitization of Austrian adolescents using molecule-based IgE profiling.

Allergy. May;72(5)

Steiner M, Hawranek T, Schneider M, Ferreira F, Horejs-Hoeck J, Harrer A, Himly M. Elevated Toll-Like Receptor-Induced CXCL8 Secretion in Human Blood Basophils from Allergic Donors Is Independent of Toll-Like Receptor Expression Levels. PLoS One , e /

Silva ES, Pinheiro CS, Quintella CM, Ferreira F, LG CP, Alcantara-Neves NM. Advances in patent applications related to allergen immunotherapy.

Expert Opin Ther Pat , /

Moraes AH, Asam C, Batista A, Almeida FC, Wallner M, Ferreira F, Valente AP. 1H, 13C and 15N resonance assignments and second structure information of Fag s 1: Fagales allergen from Fagus sylvatica. Biomol NMR Assign , /sy

McKenna OE, Asam C, Araujo GR, Roulias A, Goulart LR, Ferreira F. How relevant is panallergen sensitization in the development of allergies? Pediatr Allergy Immunol , /pai

Matricardi PM, Kleine-Tebbe J, Hoffmann HJ, Valenta R, Hilger C, Hofmaier S, Aalberse RC, Agache I, Asero R, Ballmer-Weber B, Barber D, Beyer K, Biedermann T, Bilo MB, Empty S, Bohle B, Bosshard PP, Breiteneder H, Brough HA, Caraballo L, Caubet JC, Crameri R, Davies JM, Douladiris N, Ebisawa M, PA EI, Fernandez-Rivas M, Ferreira F, Gadermaier G, Glatz M, Hamilton RG, Hawranek T, Hellings P, Hoffmann-Sommergruber K, Jakob T, Jappe U, Jutel M, Kamath SD, Knol EF, Korosec P, Kuehn A, Lack G, Lopata AL, Makela M, Morisset M, Niederberger V, Nowak-Wegrzyn AH, Papadopoulos NG, Pastorello EA, Pauli G, Platts-Mills T, Posa D, Poulsen LK, Raulf M, Sastre J, Scala E, Schmid JM, Schmid-Grendelmeier P, van Hage M, van Ree R, Vieths S, Weber R, Wickman M, Muraro A, Ollert M.

EAACI Molecular Allergology User’s Guide. Pediatr Allergy Immunol , 27 Suppl /pai

Machado Y, Freier R, Scheiblhofer S, Thalhamer T, Mayr M, Briza P, Grutsch S, Ahammer L, Fuchs JE, Wallnoefer HG, Isakovic A, Kohlbauer V, Hinterholzer A, Steiner M, Danzer M, Horejs-Hoeck J, Ferreira F, Liedl KR, Tollinger M, Lackner P, Johnson CM, Brandstetter H, Thalhamer J, Weiss R. Fold stability during endolysosomal acidification is a key factor for allergenicity and immunogenicity of the major birch pollen allergen.

J Allergy Clin Immunol , /

Himly M, Nandy A, Kahlert H, Thilker M, Steiner M, Briza P, Neubauer A, Klysner S, van Ree R, Buchheit KH, Vieths S, Ferreira F. Standardization of allergen products: 2. Detailed characterization of GMP-produced recombinant Phl p as European Pharmacopoeia reference standard. Allergy , /all

Goodman RE, Ebisawa M, Ferreira F, Sampson HA, van Ree R, Vieths S, Baumert JL, Bohle B, Lalithambika S, Wise J, Taylor SL. AllergenOnline: A peer-reviewed, curated allergen database to assess novel food proteins for potential cross-reactivity. Mol Nutr Food Res , /mnfr

Bacher P, Heinrich F, Stervbo U, Nienen M, Vahldieck M, Iwert C, Vogt K, Kollet J, Babel N, Sawitzki B, Schwarz C, Bereswill S, Heimesaat MM, Heine G, Gadermaier G, Asam C, Assenmacher M, Kniemeyer O, Brakhage AA, Ferreira F, Wallner M, Worm M, Scheffold A.

Regulatory T Cell Specificity Directs Tolerance versus Allergy against Aeroantigens in Humans. Cell , e /

Abfalter CM, Schonauer E, Ponnuraj K, Huemer M, Gadermaier G, Regl C, Briza P, Ferreira F, Huber CG, Brandstetter H, Posselt G, Wessler S. Cloning, Purification and Characterization of the Collagenase ColA Expressed by Bacillus cereus ATCC PLoS One , e /

Pablos I, Wildner S, Asam C, Wallner M, Gadermaier G. Pollen Allergens for Molecular Diagnosis Curr Allergy Asthma Rep. Apr;16(4) doi: /sz. Review.

Himly M, Nandy A, Kahlert H, Thilker M, Steiner M, Briza P, Angela N, Klysner S, van Ree R, Buchheit KH, Vieths S, Ferreira F. Standardization of allergen products: 2.

Detailed characterization of GMP-produced recombinant Phl p as European Pharmacopoeia reference standard. Allergy. Dec doi: /all [Epub ahead of print] IF

Machado Y, Freier R, Scheiblhofer S, Thalhamer T, Mayr M, Briza P, Grutsch S, Ahammer L, Fuchs JE, Wallnoefer HG, Isakovic A, Kohlbauer V, Hinterholzer A, Steiner M, Danzer M, Horejs-Hoeck J, Ferreira F, Liedl KR, Tollinger M, Lackner P, Johnson CM, Brandstetter H, Thalhamer J, Weiss R. Fold stability during endolysosomal acidification is a key factor for allergenicity and immunogenicity of the major birch pollen allergen.

J Allergy Clin Immunol. Nov pii: S(15) doi: / [Epub ahead of print] IF

Wimmer M, Alessandrini F, Gilles S, Candid U, Oeder S, Hauser M, Ring J, Ferreira F, Ernst D, Winkler JB, Schmitt-Kopplin P, Ohnmacht C, Behrendt H, Schmidt-Weber C, Traidl-Hoffmann C, Gutermuth J. Pollen-derived adenosine is a necessary cofactor for ragweed allergy. Allergy , /all

Pichler U, Hauser M, Wolf M, Bernardi ML, Gadermaier G, Weiss R, Ebner C, Yokoi H, Takai T, Didierlaurent A, Rafaiani C, Briza P, Mari A, Behrendt H, Wallner M, Ferreira F. Pectate lyase pollen allergens: sensitization profiles and cross-reactivity pattern.

PLoS One , e /

Oeder, S., Alessandrini, F., Wirz, O.F., Braun, A., Wimmer, M., Candid, U., Hauser, M., Durner, J., Ferreira, F., Ernst, D., Mempel, M., Gilles, S., Buters, J.T.M., Behrendt, H., Traidl-Hoffmann, C., Schmidt-Weber, C., Akdis, M., Gutermuth, J. Pollen-derived non-allergenic substances enhance Th2-induced IgE production in B cells. Allergy (Nov ). doi: /all (epub ahead of print). IF

Wimmer, M., Alessandrini, F., Gilles, S., Candid, U., Oeder, S., Hauser, M., Ring, J., Ferreira, F., Ernst, D., Winkler, J.B., Schmitt-Kopplin, P., Ohnmacht, C., Behrendt, H., Schmidt-Weber, C., Traidl-Hoffmann, C., Gutermuth, J. Pollen-derived adenosine is a necessary co-factor for ragweed allergy.

Allergy (Aug ) doi: /all IF

Moraes AH, Asam C, Batista A, Almeida FC, Wallner M, Ferreira F, ValenteAP. 1H, 13C and 15N resonance assignments and second structure information of Fag s 1: Fagales allergen from Fagus sylvatica. Biomol NMR Assign. Aug IF

Kitzmüller C., Zulehner, N., Roulias, A., Briza, P., Ferreira, F., Faé, I., Fischer, G.F., Bohle, B. Correlation of sensitization capacity and T-cell recognition within the Bet v 1 family.

J. Allergy Clin. Immunol. (Jul ) doi: / IF

Asam C, Hofer H, Wolf M, Aglas L, Wallner M. Tree pollen allergens-an update from a molecular perspective. Allergy. Jul doi: /all IF

Pichler, U., Hauser, M., Wolf, M., Bernardi, M.L., Gadermaier, G., Weiss, R., Ebner, C., Yokoi, H., Takai, T., Didierlaurent, D., Rafaiani, C., Briza, P., Mari, A., Behrendt, H., Wallner, M., Ferreira, F. Pectate lyase allergens: sensitization profiles and cross-reactivity pattern.

Plos One (May ) 10(5): e doi: / IF

Laimer J, Hofer H, Fritz M, Wegenkittl S, Lackner P. MAESTRO—multi agent stability prediction upon point mutations. BMC Bioinformatics. Apr 16; doi: /s IF

Dall E, Fegg JC, Briza P, Brandstetter H. Structure and mechanism of an aspartimide-dependent peptide ligase in human legumain. Angew Chem Int Ed Engl. Mar 2;54(10) doi: /anie IF

Kofler, S., Ackaert, C., Samonig, M., Asam, C., Briza, P., Horejs-Hoeck, J., Cabrele, C., Ferreira, F., Duschl, A., Huber, C., Brandstetter, H. Stabilization of the dimerich birch pollen allergen Bet v 1 impacts its immunological properties.

J.

What is ragweed allergies

Biol. Chem. () , doi: /jbc.M

Radauer, C., Nandy, A., Ferreira, F., Goodman, R.E., Larsen, J.N., Lidholm, J., Pomes, A., Raulf-Heimsoth, M., Rozynek, P., Thomas, W.R., Breiteneder, H. Update of the WHO/IUIS Allergen Nomenclarutre Database based on analysis of allergen sequences. Allergy () doi:/all

Gadermaier, G., Eichhorn, S., Vejvar, E. Weilnböck, L., Lang, R., Briza, P., Huber, C.G., Ferreira, F., Hawranek, T. Plantago lanceolata: an significant trigger of summer pollinosis with limited IgE cross-reactivity. J. Allergy Clin. Immunol. () doi: /

Asam, C., Batista, A.L., Moraes, A.H.

de Paula, V.S., Almeida, F.C.L., Aglas, L., Kitzmüller, C., Bohle, B., Ebner, C., Ferreira, F., Wallner, M., Valente, A.P. Bet v 1 – a Trojan horse for little ligands boosting allergic sensitization? Clin Exp Allergy () doi: /cea

Ferreira, F., Wolf, M., Wallner, M. Molecular approach to allergy diagnosis and Med J () doi: /ymj

Grutsch, S., Fuchs, J.F., Fischer, R., Kofler, S., Bibi, M., Asam, C., Wallner, M., Ferreira, F., Brandstetter, H., Liedl, K.R., Tollinger, M.

Ligand binding modulates structural dynamics and compactness of the major birch pollen allergen. Biophys. J. () doi: /

Moraes, A.H., Ackerbauer, D., Kostadinova, M., Bublin, M., de Oliveira, G.A., Ferreira, F., Almeida, F.C., Breiteneder, H., Valente, A.P. Solution and high-pressure NMR studies of the structure, dynamics, and stability of the cross-reactive allergenic cod parvalbumin Gad m 1. Proteins () doi: /prot

Delfi, S., Zwicker, C., Vejvar, E., Kitzmüller, C., Gadermaier, G., Nagl, B., Vrtala, S., Briza, P., Zlabinger, G.J., Jahn-Schmid, B., Ferreira, F., Bohle, B.

Glutathione-S-transferase: a minor allergen in birch pollen due to limited release from hydrated pollen. Plos One () 9(9):e doi: /

Ackaert, C., Kofler, S., Horejs-Höck, J., Zulehner, N., Asam, C., von Grafenstein, S., Fuchs, J.E., Briza, P., Liedl, K.R., Bohle, B., Ferreira, F., Brandstetter, H., Oostingh, G.J., Duschl, A. The impact of nitration on the structure and immunogenicity of the major birch pollen allergen Bet v Plos One () e doi: /

Roulias, A., Pichler, U., Hauser, M., Himly, M., Hofer, H., Lackner, P., Ebner, C., Briza, P., Bohle, B., Egger, M., Wallner, M., Ferreira, F. Differences in the intrinsic immunogenicity and allergenicity of Bet v 1 and related food allergens revealed by site-directed mutagenesis.

Feb;69(2) Epub Nov doi: /all

Pichler, U., Hauser, M., Hofer, H., Himly, M., Hoflehner, E., Steiner, M., Mutschlechner, S., Hufnagl, K., Ebner, C., Mari, A., Briza, P., Bohle, B., Wiedermann, U., Ferreira, F., Wallner, M. Allergen hybrids – next generation vaccines for Fagales pollen immunotherapy. Clin Exp Allergy. Mar;44(3) doi: /cea

Hofbauer SW, Krenn PW, Ganghammer S, Asslaber D, Pichler U, Oberascher K, Henschler R, Wallner M, Kerschbaum H, Greil R, Hartmann TN. Tiam1/Rac1 signals contribute to the proliferation and chemoresistance, but not motility, of chronic lymphocytic leukemia cells.

Blood. Apr 3;(14) doi: /blood

Deressa T, Stoecklinger A, Wallner M, Himly M, Kofler S, Hainz K, Brandstetter H, Thalhamer J, Hammerl P. Structural Integrity of the Antigen Is a Determinant for the Induction of T-Helper Type-1 Immunity in Mice by Gene Gun Vaccines against Beta-Galactosidase. PLoS One. Jul 15;9(7):e doi: /

Gadermaier G. Non-specific lipid transfer proteins: a protein family in search of an allergenic pattern. Int Arch Allergy Immunol. ;(3) doi: /

Reinmuth-Selzle K, Ackaert C, Kampf CJ, Samonig M, Shiraiwa M, Kofler S, Yang H, Gadermaier G, Brandstetter H, Huber CG, Duschl A, Oostingh GJ, Pöschl U. Nitration of the birch pollen allergen Bet v efficiency and site-selectivity of liquid and gaseous nitrating agents.J Proteome Res.

Mar 7;13(3) doi: /prh.

Schülke S, Wolfheimer S, Gadermaier G, Wangorsch A, Siebeneicher S, Briza P, Spreitzer I, Schiller D, Loeschner B, Uematsu S, Ryffel B, Akira S, Waibler Z, Vieths S, Toda M, Scheurer S. Prevention of intestinal allergy in mice by rflaA:Ova is associated with enforced antigen processing and TLR5-dependent IL secretion by mDC. PLoS One. Feb 7;9(2):e doi: /

Heilmann M, Wellner A, Gadermaier G, Ilchmann A, Briza P, Krause M, Nagai R, Burgdorf S, Scheurer S, Vieths S, Henle T, Toda M. Ovalbumin modified with pyrraline, a Maillard reaction product, shows enhanced T-cell immunogenicity.

J Biol Chem. Mar 14;(11) doi: /jbc.M

Zuidmeer-Jongejan L, Fernández-Rivas M, Winter MG, Akkerdaas JH, Summers C, Lebens A, Knulst AC, Schilte P, Briza P, Gadermaier G, van Ree R. Oil body-associated hazelnut allergens including oleosins are underrepresented in diagnostic extracts but associated with severe symptoms. Clin Transl Allergy. Feb 2;4(1) doi: /

Stemeseder T, Hemmer W, Hawranek T, Gadermaier G.

Marker allergens of weed pollen — basic considerations and diagnostic benefits in the clinical routine: Part 16 of the Series Molecular Allergology. Allergo J Int. ;23(8) Epub Dec Review.

Wallner M, Pichler U, Ferreira F. Recombinant allergens for pollen immunotherapy. Immunotherapy. Dec;5(12) doi: /imt

Roulias A, Pichler U, Hauser M, Himly M, Hofer H, Lackner P, Ebner C, Briza P, Bohle B, Egger M, Wallner M, Ferreira F. Differences in the intrinsic immunogenicity and allergenicity of Bet v 1 and related food allergens revealed by site-directed mutagenesis.

Allergy. Feb;69(2) doi: /all Epub Nov

Acevedo N, Mohr J, Zakzuk J, Samonig M, Briza P, Erler A, Pomés A, Huber CG, Ferreira F, Caraballo L. Proteomic and immunochemical characterization of glutathione transferase as a new allergen of the nematode Ascaris lumbricoides. PLoS One. Nov 4;8(11):e doi: / eCollection

Pichler U, Asam C, Weiss R, Isakovic A, Hauser M, Briza P, Ferreira F, Wallner M. The fold variant BM4 is beneficial in a therapeutic Bet v 1 mouse model. Biomed Res Int. ; doi: // Epub Sep

Vejvar E, Himly M, Briza P, Eichhorn S, Ebner C, Hemmer W, Ferreira F, Gadermaier G. Allergenic relevance of nonspecific lipid transfer proteins 2: Identification and characterization of Api g 6 from celery tuber as representative of a novel IgE-binding protein family.

Mol Nutr Food Res. Nov;57(11) doi: /mnfr Epub Aug 5.

Gadermaier G, Hauser M, Ferreira F. Allergens of weed pollen: An overview on recombinant and natural molecules. Methods. Mar 1;66(1) doi: / Epub Jun Review.

Santos KS, Gadermaier G, Vejvar E, Arcuri HA, Galvão CE, Yang AC, Resende VM, Martins Cde O, Himly M, Mari A, Liso M, Pomponi D, Breiteneder H, Wagner S, Kalil J, Ferreira F, Castro FF. Novel allergens from ancient foods: Man e 5 from manioc (Manihot esculenta Crantz) cross reacts with Hev b 5 from latex. Mol Nutr Food Res. Jun;57(6) doi: /mnfr Epub Mar

Schulten V, Greenbaum JA, Hauser M, McKinney DM, Sidney J, Kolla R, Lindestam Arlehamn CS, Oseroff C, Alam R, Broide DH, Ferreira F, Grey HM, Sette A, Peters B. Previously undescribed grass pollen antigens are the major inducers of T helper 2 cytokine-producing T cells in allergic individuals.

Proc Natl Acad Sci U S A. Feb 26;(9) doi: /pnas Epub Feb Erratum in: Proc Natl Acad Sci U S A. Mar 26;(13) Ferreira-Briza, Fatima [corrected to Ferreira, Fatima]. Proc Natl Acad Sci U S A. May 21;(21)

Gao ZS, Yang ZW, Wu SD, Wang HY, Liu ML, Mao WL, Wang J, Gadermaier G, Ferreira F, Zheng M, van Ree R. Peach allergy in China: a dominant role for mugwort pollen lipid transfer protein as a primary sensitizer. J Allergy Clin Immunol. Jan;(1)e doi: / Epub Aug No abstract available.

Kanter U, Heller W, Durner J, Winkler JB, Engel M, Behrendt H, Holzinger A, Braun P, Hauser M, Ferreira F, Mayer K, Pfeifer M, Ernst D. Molecular and immunological characterization of ragweed (Ambrosia artemisiifolia L.) pollen after exposure of the plants to elevated ozone over a whole growing season.

PLoS One. Apr 18;8(4):e doi: / Print

Weinberger EE, Himly M, Myschik J, Hauser M, Altmann F, Isakovic A, Scheiblhofer S, Thalhamer J, Weiss R. Generation of hypoallergenic neoglycoconjugates for dendritic cell targeted vaccination: a novel tool for specific immunotherapy. J Control Release. Jan 28;(2) doi: /l Epub Nov

Arshad SH, Dharmage SC, Ferreira F, Fixman ED, Gadermaier G, Hauser M, Sampson AP, Teran LM, Wallner M, Wardlaw AJ. Developments in the field of allergy in through the eyes of Clinical and Experimental Allergy. Clin Exp Allergy. Dec;42(12) doi: /cea Review.

Kitzmüller C, Wallner M, Deifl S, Mutschlechner S, Walterskirchen C, Zlabinger GJ, Ferreira F, Bohle B.

A hypoallergenic variant of the major birch pollen allergen shows distinct characteristics in antigen processing and T-cell activation. Allergy. Nov;67(11) doi: /all Epub Sep

Golias J, Schwarzer M, Wallner M, Kverka M, Kozakova H, Srutkova D, Klimesova K, Sotkovsky P, Palova-Jelinkova L, Ferreira F, Tuckova L. Heat-induced structural changes affect OVA-antigen processing and reduce allergic response in mouse model of food allergy.

PLoS One. ;7(5):e doi: / Epub May Erratum in: PLoS One. ;7(8). doi: /annotation/dc-aadd

Karle AC, Oostingh GJ, Mutschlechner S, Ferreira F, Lackner P, Bohle B, Fischer GF, Vogt AB, Duschl A. Nitration of the pollen allergen bet v enhances the presentation of bet v 1-derived peptides by HLA-DR on human dendritic cells. PLoS One. ;7(2):e doi: / Epub Feb

Filep S, Tsay A, Vailes LD, Gadermaier G, Ferreira F, Matsui E, King EM, Chapman MD. Specific allergen concentration of WHO and FDA reference preparations measured using a multiple allergen standard.

J Allergy Clin Immunol. May;(5) doi: / Epub Jan No abstract available.

Jahn-Schmid B, Hauser M, Wopfner N, Briza P, Berger UE, Asero R, Ebner C, Ferreira F, Bohle B. Humoral and cellular cross-reactivity between Amb a 1, the major ragweed pollen allergen, and its mugwort homolog Art v 6. J Immunol. Feb 1;(3) doi: /jimmunol Epub Dec

Siegert M, Pertl-Obermeyer H, Gadermaier G, Ferreira F, Obermeyer G. Expression of the major mugwort pollen allergen Art v 1 in tobacco plants and cell cultures: problems and perspectives for allergen production in plants. Plant Cell Rep. Mar;31(3) doi: /s Epub Dec

Filep S, Tsay A, Vailes L, Gadermaier G, Ferreira F, Matsui E, King EM, Chapman MD. A multi-allergen standard for the calibration of immunoassays: CREATE principles applied to eight purified allergens.

Allergy. Feb;67(2) doi: /jx. Epub Nov

Kofler S, Asam C, Eckhard U, Wallner M, Ferreira F, Brandstetter H. Crystallographically mapped ligand binding differs in high and low IgE binding isoforms of birch pollen allergen Bet v 1. J Mol Biol. Sep 7;(1) doi: / Epub May

Zaborsky N, Brunner M, Wallner M, Himly M, Karl T, Schwarzenbacher R, Ferreira F, Achatz G. Response to Detection and analysis of unusual features in the structural model and structure-factor data of a birch pollen allergen. Acta Crystallogr Sect F Struct Biol Cryst Commun. Apr 1;68(Pt 4) doi: /S Epub Mar

Hoy B, Geppert T, Boehm M, Reisen F, Plattner P, Gadermaier G, Sewald N, Ferreira F, Briza P, Schneider G, Backert S, Wessler S.

Distinct roles of secreted HtrA proteases from gram-negative pathogens in cleaving the junctional protein and tumor suppressor E-cadherin. J Biol Chem. Mar 23;(13) doi: /jbc.C Epub Feb

Hauser M, Asam C, Himly M, Palazzo P, Voltolini S, Montanari C, Briza P, Bernardi ML, Mari A, Ferreira F, Wallner M.Bet v 1-like pollen allergens of multiple Fagales species can sensitize atopic individuals.Clin Exp Allergy. Dec;41(12)

Gadermaier G, Hauser M, Egger M,Ferrara R, Briza P, Santos KS, Zennaro D, Girbl T, Zuidmeer-Jongejan L, Mari A, Ferreira F. Sensitization prevalence, antibody cross-reactivity and immunogenic peptide profile of Api g 2, the non-specific lipid transfer protein 1 of celery.PLoS One.

;6(8):e Epub Aug


Santos KS, Galvao CE, Gadermaier G, Resende VM, de Oliveira Martins C, Misumi DS, Yang AC, Ferreira F, Palma MS, Kalil J, Castro FF.
Allergic reactions to manioc (Manihot esculenta Crantz): identification of novel allergens with potential involvement in latex-fruit syndrome.
J Allergy Clin Immunol. Dec;(6)

Pasqualini S, Tedeschini E, Frenguelli G, Wopfner N, Ferreira F, D´Amato G, Ederli L. Ozone affects pollen viability and NAD(P)H oxidase release from Ambrosia artemisiifolia pollen.
Environ Pollut.

Oct;(10)

Egger M, Alessandri C, Wallner M, Briza P, Zennaro D, Mari A, Ferreira F, Gadermaier G. Is aboriginal food less allergenic? Comparing IgE-reactivity of eggs from modern and ancient chicken breeds in a cohort of allergic children.
PLoS One. Apr 28;6(4):e

Gadermaier G, Egger M, Girbl T, Erler A, Harrer A, Vejvar E, Liso M, Richter K, Zuidmeer L, Mari A, Ferreira F. Molecular characterization of Api g 2, a novel allergenic member of the lipid-transfer protein 1 family from celery stalks.
Mol Nutr Food Res.

Apr;55(4)

Wallner M, Hauser M, Himly M, Zaborsky N, Mutschlechner S, Harrer A, Asam C, Pichler U, van Ree R, Briza P, Thalhamer J, Bohle B, Achatz G, Ferreira F. Reshaping the Bet v 1 fold modulates T(H) polarization.
J Allergy Clin Immunol. Jun;(6)e9.

Erler A, Hawranek T, Krückemeier L, Asam C, Egger M, Ferreira F, Briza P. Proteomic profiling of birch (Betula verrucosa) pollen extracts from diverse origins.
Proteomics.

Apr;11(8)

Egger M, Jürets A, Wallner M, Briza P, Ruzek S, Hainzl S, Pichler U, Kitzmüller C, Bohle B, Huber CG, Ferreira F. Assessing protein immunogenicity with a dendritic cell line-derived endolysosomal degradome.
PLoS One. Feb 16;6(2):e

Schulten V, Nagl B, Scala E, Bernardi ML, Mari A, Ciardiello MA, Lauer I, Scheurer S, Briza P, Jürets A, Ferreira F, Jahn-Schmid B, Fischer GF, Bohle B.

Pru p 3, the nonspecific lipid transfer protein from peach, dominates the immune response to its homolog in hazelnut. Allergy. Aug;66(8)

D´Avino R, Bernardi ML, Wallner M, Palazzo P, Camardella L, Tuppo L, Alessandri C, Breiteneder H, Ferreira F, Ciardiello MA, Mari A.
Kiwifruit Act d 11 is the first member of the ripening-related protein family identified as an allergen. Allergy. Jul;66(7)

Aiub CA, Gadermaier G, Silva IO, Felzenszwalb I, Pinto LF, Ferreira F, Eckl P.N-nitrosodiethylamine genotoxicity evaluation: a cytochrome P induction study in rat hepatocytes.

Genet Mol Res. Oct 5;10(4)

Aiub CA, Gadermaier G, Oliveira I, Felzenszwalb I, Ferreira F, Ribeiro Pinto LF, Eckl P.N-Nitrosodiethylamine genotoxicity in primary rat hepatocytes: effects of cytochrome P induction by phenobarbital. Toxicol Lett. Oct 10;(2)

Gadermaier G, Egger M, Girbl T, Erler A, Harrer A, Vejvar E, Liso M, Richter K, Zuidmeer L, Mari A, Ferreira F. Molecular characterization of Api g 2, a novel allergenic member of the lipid-transfer protein 1 family from celery stalks.
Mol Nutr Food Res.

Dec

Zaborsky N, Brunner M, Wallner M, Himly M, Karl T, Schwarzenbacher R, Ferreira F, Achatz G. Antigen aggregation decides the fate of the allergic immune response. J Immunol. Jan 15;(2)

Harrer A, Lang R, Grims R, Braitsch M, Hawranek T, Aberer W, Vogel L, Schmid W, Ferreira F, Himly M. Diclofenac hypersensitivity: antibody responses to the parent drug and relevant metabolites. PLoS One. Oct 28;5(10):e

Acevedo N, Erler A, Briza P, Puccio F, Ferreira F, Caraballo L.
Allergenicity of Ascaris lumbricoides tropomyosin and IgE sensitization among asthmatic patients in a tropical environment.

Int Arch Allergy Immunol. ;(3) Epub Sep

Weiss R, Scheiblhofer S, Roesler E, Ferreira F, Thalhamer J.
Prophylactic mRNA vaccination against allergy. Curr Opin Allergy Clin Immunol. Dec;10(6)

Razzera G, Gadermaier G, de Paula V, Almeida MS, Egger M, Jahn-Schmid B, Almeida FC, Ferreira F, Valente AP.
Mapping the interactions between a major pollen allergen and human IgE antibodies. Structure.

Aug 11;18(8)

Jahn-Schmid B, Wopfner N, Hubinger G, Asero R, Ebner C, Ferreira F, Bohle B. The T-cell response to Amb a 1 is characterized by 3 dominant epitopes and multiple MHC restriction elements. J Allergy Clin Immunol. Nov;(5), e

Egger M, Hauser M, Mari A, Ferreira F, Gadermaier G.
The role of lipid transfer proteins in allergic diseases. Curr Allergy Asthma Rep. Sep;10(5) Review.

Léonard R, Wopfner N, Pabst M, Stadlmann J, Petersen BO, Duus JØ, Himly M, Radauer C, Gadermaier G, Razzazi-Fazeli E, Ferreira F, Altmann F. A new allergen from ragweed (Ambrosia artemisiifolia) with homology to art v 1 from mugwort.Biol Chem.

Aug 27;(35)


Magler I, Nüss D, Hauser M, Ferreira F, Brandstetter H.
Molecular metamorphosis in polcalcin allergens by EF-hand rearrangements and domain swapping. FEBS Jun;(12)

Thalhamer T, Dobias H, Stepanoska T, Pröll M, Stutz H, Dissertori O, Lackner P, Ferreira F, Wallner M, Thalhamer J, Hartl A. Designing hypoallergenic derivatives for allergy treatment by means of in silico mutation and screening.Allergy Clin Immunol. Apr;(4)e

Hauser M, Roulias A, Ferreira F, Egger M. Panallergens and their impact on the allergic patient.

Allergy Asthma Clin Immunol. Jan 18;6(1)

Valenta R, Ferreira F, Focke-Tejkl M, Linhart B, Niederberger V, Swoboda I, Vrtala S.
From allergen genes to allergy vaccines. Annu Rev Immunol. Mar; Review.

Mutschlechner S, Egger M, Briza P, Wallner M, Lackner P, Karle A, Vogt AB, Fischer GF, Bohle B, Ferreira F.Naturally processed T cell-activating peptides of the major birch pollen allergen. J Allergy Clin Immunol. Mar;(3), ee2.

Gadermaier G, Jahn-Schmid B, Vogel L, Egger M, Himly M, Briza P, Ebner C, Vieths S, Bohle B, Ferreira F.Targeting the cysteine-stabilized fold of Art v 1 for immunotherapy of Artemisia pollen allergy.
Mol Immunol.

Mar;47(6)

Smole U, Balazs N, Hoffmann-Sommergruber K, Radauer C, Hafner C, Wallner M, Ferreira F, Grössinger R, de Jong EC, Wagner S, Breiteneder H.Differential T-cell responses and allergen uptake after exposure of dendritic cells to the birch pollen allergens Bet v , Bet v and Bet v
Immunobiology. Nov;(11)

Harrer A, Egger M, Gadermaier G, Erler A, Hauser M, Ferreira F, Himly M.Characterization of plant food allergens: an overview on physicochemical and immunological techniques.
Mol Nutr Food Res.

Jan;54(1) Review.

Roesler E, Weiss R, Weinberger EE, Fruehwirth A, Stoecklinger A, Mostböck S, Ferreira F, Thalhamer J, Scheiblhofer S. Immunize and disappear-safety-optimized mRNA vaccination with a panel of 29 allergens. J Allergy Clin Immunol. Nov;(5)e

Egger M, Hauser M, Himly M, Wopfner N, Wallner M, Ferreira F. Development of recombinant allergens for diagnosis and therapy. Front Biosci (Elite Ed). Jun 1;

Gadermaier G, Harrer A, Girbl T, Palazzo P, Himly M, Vogel L, Briza P, Mari A, Ferreira F.

Isoform identification and characterization of Art v 3, the lipid-transfer protein of mugwort pollen. Mol Immunol. Jun;46(10)

Gruber P, Gadermaier G, Bauer R, Weiss R, Wagner S, Leonard R, Breiteneder H, Ebner C, Ferreira F, Egger M. Role of the polypeptide backbone and post-translational modifications in cross-reactivity of Art v 1, the major mugwort pollen allergen. Biol Chem. May-Jun;()

Wopfner N, Jahn-Schmid B, Schmidt G, Christ T, Hubinger G, Briza P, Bohle B, Vogel L, Ebner C, Asero R, Ferreira F, Schwarzenbacher R.

The alpha and beta subchain of Amb a 1, the major ragweed-pollen allergen show divergent reactivity at the IgE and T-cell level. Mol Immunol. Mar 5.

Himly M, Nony E, Chabre H, Van Overtvelt L, Neubauer A, van Ree R, Buchheit KH, Vieths S, Moingeon P, Ferreira F. Standardization of allergen products: 1. Detailed characterization of GMP-produced recombinant Bet v as biological reference preparation.

Allergy. Jan

Wallner M, Erler A, Hauser M, Klinglmayr E, Gadermaier G, Vogel L, Mari A, Bohle B, Briza P, Ferreira F. Immunologic characterization of isoforms of Car b 1 and Que a 1, the major hornbeam and oak pollen allergens.
Allergy. Mar;64(3) Epub Jan

Klinglmayr E, Hauser M, Zimmermann F, Dissertori O, Lackner P, Wopfner N, Ferreira F, Wallner M.
Identification of B-cell epitopes of Bet v 1 involved in cross-reactivity with food allergens. Array-based profiling of ragweed and mugwort pollen allergens.

Allergy. Jan 9.

Dedic A, Gadermaier G, Vogel L, Ebner C, Vieths S, Ferreira F, Egger M. Immune recognition of novel isoforms and domains of the mugwort pollen major allergen Art v 1. Array-based profiling of ragweed and mugwort pollen allergens.
Mol Immunol. Jan;46(3) Epub Dec 2.

Gadermaier G, Wopfner N, Wallner M, Egger M, Didierlaurent A, Regl G, Aberger F, Lang R, Ferreira F, Hawranek T. Array-based profiling of ragweed and mugwort pollen allergens.

Allergy.

What is ragweed allergies

Nov;63(11)

Mohapatra SS, San-Juan-Vergara H, Wopfner N, Ferreira F. Experimental forms of allergen immunotherapy with modified allergens and adjuvants. Clin Allergy Immunol. ; Review.

Chapman MD, Ferreira F, Villalba M, Cromwell O, Bryan D, Becker WM, Fernández-Rivas M, Durham S, Vieths S, van Ree R. CREATE consortium. The European Union CREATE project: a model for international standardization of allergy diagnostics and vaccines.

J Allergy Clin Immunol. Nov;(5)e2.

Jahn-Schmid B, Sirven P, Leb V, Pickl WF, Fischer GF, Gadermaier G, Egger M, Ebner C, Ferreira F, Maillére B, Bohle B. Characterization of HLA class II/peptide-TCR interactions of the immunodominant T cell epitope in Art v 1, the major mugwort pollen allergen.J Immunol. Sep 1;(5)

Wopfner N, Gruber P, Wallner M, Briza P, Ebner C, Mari A, Richter K, Vogel L, Ferreira F.
Molecular and immunological characterization of novel weed pollen pan-allergens. Allergy. Jul;63(7)

van Ree R, Chapman MD, Ferreira F, Vieths S, Bryan D, Cromwell O, Villalba M, Durham SR, Becker WM, Aalbers M, André C, Barber D, Cistero Bahima A, Custovic A, Didierlaurent A, Dolman C, Dorpema JW, Di Felice G, Eberhardt F, Fernandez Caldas E, Fernandez Rivas M, Fiebig H, Focke M, Fötisch K, Gadermaier G, Das RG, Gonzalez Mancebo E, Himly M, Kinaciyan T, Knulst AC, Kroon AM, Lepp U, Marco FM, Mari A, Moingeon P, Monsalve R, Neubauer A, Notten S, Ooievaar-de Heer P, Pauli G, Pini C, Purohit A, Quiralte J, Rak S, Raulf-Heimsoth M, San Miguel Moncin MM, Simpson B, Tsay A, Vailes L, Wallner M, Weber B.The CREATE project: development of certified reference materials for allergenic products and validation of methods for their quantification.

Allergy. Mar;63(3) Review.

Wopfner N, Bauer R, Thalhamer J, Ferreira F, Chapman M.Immunologic analysis of monoclonal and immunoglobulin E antibody epitopes on natural and recombinant Amb a 1.Clin Exp Allergy. Jan;38(1)

Oberhuber C, Ma Y, Wopfner N, Gadermaier G, Dedic A, Niggemann B, Maderegger B, Gruber P, Ferreira F, Scheiner O, Hoffmann-Sommergruber K.Prevalence of IgE-binding to Art v 1, Art v 4 and Amb a 1 in mugwort-allergic patients.Int Arch Allergy Immunol. ;(2)

Westritschnig K, Linhart B, Focke-Tejkl M, Pavkov T, Keller W, Ball T, Mari A, Hartl A, Stöcklinger A, Scheiblhofer S, Thalhamer J, Ferreira F, Vieths S, Vogel L, Böhm A, Valent P, Valenta R. A hypoallergenic vaccine obtained by tail-to-head restructuring of timothy grass pollen profilin, Phl p 12, for the treatment of cross-sensitization to profilin.J Immunol.

Dec 1;(11)

Wallner M, Stöcklinger A, Thalhamer T, Bohle B, Vogel L, Briza P, Breiteneder H, Vieths S, Hartl A, Mari A, Ebner C, Lackner P, Hammerl P, Thalhamer J, Ferreira F.
Allergy multivaccines created by DNA shuffling of tree pollen allergens.J Allergy Clin Immunol. Aug;(2)

Stoecklinger A, Grieshuber I, Scheiblhofer S, Weiss R, Ritter U, Kissenpfennig A, Malissen B, Romani N, Koch F, Ferreira F, Thalhamer J, Hammerl P.
Epidermal langerhans cells are dispensable for humoral and cell-mediated immunity elicited by gene gun immunization.
J Immunol. Jul 15;(2)

Wallner M, Briza P, Thalhamer J, Ferreira F.Specific immunotherapy in pollen allergy.Curr Opin Mol Ther.

Apr;9(2) Review.

Wopfner N, Dissertori O, Ferreira F, Lackner P.
Calcium-binding proteins and their role in allergic diseases.Immunol Allergy Clin North Am. Feb;27(1) Review.

Chapman MD, Pomés A, Breiteneder H, Ferreira F.
Nomenclature and structural biology of allergens.J Allergy Clin Immunol. Feb;(2) Review.

Wild C, Wallner M, Hufnagl K, Fuchs H, Hoffmann-Sommergruber K, Breiteneder H, Scheiner O, Ferreira F, Wiedermann U. A recombinant allergen chimer as novel mucosal vaccine candidate for prevention of multi-sensitivities.
Allergy. Jan;62(1)

Mutschlechner S, Ferreira F. Engineering allergens.

Eur Ann Allergy Clin Immunol. Sep;38(7) Review.

Zuidmeer L, van Leeuwen WA, Kleine Budde I, Breiteneder H, Ma Y, Mills C, Sancho AI, Meulenbroek EJ, van de Weg E, Gilissen L, Ferreira F, Hoffmann-Sommergruber K, van Ree R. Allergenicity assessment of apple cultivars: hurdles in quantifying labile fruit allergens.Int Arch Allergy Immunol. ;(3)

Ma Y, Zuidmeer L, Bohle B, Bolhaar ST, Gadermaier G, Gonzalez-Mancebo E, Fernandez-Rivas M, Knulst AC, Himly M, Asero R, Ebner C, van Ree R, Ferreira F, Breiteneder H, Hoffmann-Sommergruber K.Characterization of recombinant Mal d 4 and its application for component-resolved diagnosis of apple allergy.Clin Exp Allergy.

Aug;36(8)

Radauer, C., Willerroider, M., Fuchs, H., Hoffmann-Sommergruber, K., Thalhamer, J., Ferreira, F., Scheiner, O., Breiteneder, H. Cross-reactive and species-specific immunoglobuliin E epitopes of plant profilins: an experimental and structure-based analysis.Clin Exp Allergy. Jul;36(7)

Bauer R, Scheiblhofer S, Kern K, Gruber C, Stepanoska T, Thalhamer T, Hauser-Kronberger C, Alinger B, Zoegg T, Gabler M, Ferreira F, Hartl A, Thalhamer J, Weiss R.Generation of hypoallergenic DNA vaccines by forced ubiquitination: preventive and therapeutic effects in a mouse model of allergy.
J Allergy Clin Immunol.

Jul;(1)

Scheiblhofer S, Gabler M, Leitner WW, Bauer R, Zoegg T, Ferreira F, Thalhamer J, Weiss R.Inhibition of type I allergic responses with nanogram doses of replicon-based DNA vaccines.Allergy. Jul;61(7)

Asero R, Wopfner N, Gruber P, Gadermaier G, Ferreira F.Artemisia and Ambrosia hypersensitivity: co-sensitization or co-recognition?Clin Exp Allergy. May;36(5)

Ferreira F, Briza P, Inführ D, Schmidt G, Wallner M, Wopfner N, Thalhamer J, Achatz G.Modified recombinant allergens for safer immunotherapy.Inflamm Allergy Drug Targets.

Jan;5(1) Review.

Jahn-Schmid, B., Fischer, G., Bohle, B., Fae, I., Gadermaier, G., Dedic, A., Ferreira, F., Ebner, C. Antigen presentation of the immunodominant T cell epitope of the major mugwort pollen allergen, Art v 1, is associated with the expression of HLA-DRB1*J. Allergy Clin. Immunol. ,

Leonard, R., Petersen, B.O., Himly, M., Kaar, W., Wopfner, N., Kolarich, D., van Ree, R., Ebner, C., Duus, J.Ø., Ferreira, F., Altmann, F. Two novel types of O-glycans on the mugwort pollen allergen Art v 1 and their role in antibody binding.
J.

Biol. Chem. ,

Hebenstreit, D., Ferreira, F. Structural changes in calcium-binding allergens: use of circular dichroism to study binding characteristics.Allergy ,

Bolhaar, S.T.H.P., Zuidmeer, L., Ma, Y., Ferreira, F., Bruijnzeel-Koomen, C.A.F.M., Hoffmann-Sommergruber, van Ree, R., Knulst, A.C. A mutant of the major apple allergen, Mal d 1 demonstrating hypo-allergenicity in target organ by DBPCFC.Clin. Exp. Allergy ,

Obermeyer, G., Ferreira, F. Can we predict or avoid the allergenic potential of genetically modified organisms?Int.

Arch. Allergy Immunol. ,

Wopfner, N., Gadermaier, G., Egger, M., Asero, R., Ebner, C., Jahn-Schmidt, B., Ferreira, F.The spectrum of allergens in ragweed and mugwort pollen.
Int. Arch. Allergy Immunol. ,

Hartl., A., Hochreiter, R., Stepanoska, T., Ferreira, F., Thalhamer, J. Characterization of the protective and therapeutic efficiency of a DNA vaccine encoding the major birch pollen allergen Bet v 1a.Allergy ,

Ferreira, F., Hawranek, T., Gruber, P., Wopfner, N., Mari, A. Allergic cross-reactivity: from gene to the clinic.Allergy ,

Wallner, M., Gruber, P., Radauer, C., Maderegger, B., Susani, M., Hoffman-Sommergruber, K., Ferreira, F.

Lab scale and medium production of recombinant allergens in Escherichia coli.Methods ,

Obermeyer, G., Gehwolf, R., Sebesta, W., Hamilton, N., Gadermaier, G., Ferreira, F., Commandeur, U., Fisher, R., Bentrup, F.W. Over-expression and production of plant allergens by molecular farming strategies.Methods ,

Ferreira, F., Wallner, M., Thalhamer, J.
Costumized antigens and immunomodulations for desensitizing allergic patients.Adv. Immunol. ,

Neudecker, P., Nerkamp, J., Eisenmann, A., Nourse, A., Lauber, T., Schweimer, K., Lehmann, K., Ferreira, F., Rösch, P. Solution structure, dynamics, and hydrodynamics of the calcium-bound cross-reactive birch pollen allergen Bet v 4 reveal a canonical monomeric two EF-hand assembly with a regulatory function.J.

Mol. Biol. ,

Gadermaier, G., Dedic, A., Obermeyer, G., Candid, S., Himly, M., Ferreira, F.Biology of weed pollen allergens.Current Allergy and Asthma Rep. ,

Markovic-Housley, Z., Degano, M., Lamba, D., von Roepenack-Lahaye, E., Clemens, S., Susani, M., Ferreira, F., Scheiner, O., Breiteneder, H. Crystal structure of a hypoallergenic isoform of the major birch pollen allergen Bet v 1 and its likely biological function as a plant steroid carrier.J. Mol. Biol. ,

Himly, M., Jahn-Schmid, B., Pittertschatscher, K., Bohle, B., Grubmayr, K., Ferreira, F., Ebner, H., Ebner, C. IgE-mediated immediate-type hypersensitivity to the pyrazolone drug propyphenazone.J.

Allergy Clin. Immunol. ,

Schmid-Grendelmeier, P., Holzmann,D., Himly, M., Weichel, M., Tresch, S., Ruckert, B., Menz, G., Ferreira, F., Blaser, K., Wüthrich, B., Crameri, R. Native and recombinant Art v 1 are capable to induce humoral and T cell mediated in vitro and in vivo responses in mugwort allergy.J. Allergy Clin. Immunol ,

Krebitz, M., Wagner, B., Ferreira, F., Peterbauer, C., Campillo, N., Witty, M., Kolarich, D., Steinkellner, H., Scheiner, O., Breiteneder, H. Plant-based heterologous expression of Mal d 2, a thaumatin-like protein and allergen of apple (Malus domestica), and its characterization as an antifungal-protein.J.

Mol. Biol. ,

Hochreiter, R., Stepanoska, T., Ferreira, F., Valenta, R., Vrtala, S., Thalhamer, J., Hartl, A. Prevention of allergen-specific IgE production and suppression of an estabished Th2-type response by immunization with DNA encoding hypoallergenic derivatives of Bet v 1, the major birch pollen allergen.Eur. J. Immunol. ,

Bauer, R., Himly, M., Dedic, A., Ferreira, F., Josef Thalhamer, J., Hartl, A. Optimization of codon usage is required for effective genetic immunization against Art v 1, the major allergen of mugwort pollen.Allergy ,

Hochreiter, R., Ferreira, F., Thalhamer, J., Hammerl, P. Th1-promoting DNA immunization against allergens modulates the ratio of IgG1/IgG2a but does not affect anaphylactic potential of IgG1 antibodies: no evidence for the synthesis of non-anaphylactic IgG1.J.

Allergy Clin. Immunol. ,

Willerroider, M., Fuchs, H., Ballmer-Weber, B., Focke, M., Susani, M., Thalhamer, J., Ferreira, F., Wüthrich, B., Scheiner, O., Breiteneder, H., Hoffmann-Sommergruber, K. Cloning and Molecular and Immunological Characterization of Two New Food Allergens, Lyc e 1 and Cap a 2, Profilins From Bell Pepper (Capsicum annuum) and TomatoInt. Arch Allergy Immunol. ,

Mari, A., Wallner, M., Ferreira, F.

Fagales pollen allergy in a birch-free area: a population survey using Fagales pollen extracts and birch recombinant allergens (rBet v 1, rBet v 2, rBet v 4).Clin. Exp. Allergy ,

Hiller, R., Laffer, S., Harwanegg, C., Huber, M., Schmid, W., Twardosz, A., Becker, W.M., Blaser, K., Breiteneder, H., Chapman, M., Crameri, R., Duchene, M., Ferreira, F., Fiebig., H., et al. Microarrayed allergen molecules: Diagnostic gatekeepers for allergy treatment.FASEB J.

(January 14, ) /fjfje

Weiss, R., Scheiblhofer, S., Freund, J., Ferreira, F., Livey, I., Thalhamer, J. Gene gun bombardment with gold particles displays a specific Th2-promoting signal that over-rules the Th1-inducing effect of immunostimulatory CpG motifs in DNA vaccines.Vaccine ,

Ferreira, F., Wallner, M., Breiteneder, H., Hartl, A., Thalhamer, J., Ebner, C. Genetic engineering of allergens: Future therapeutic products.Int. Arch. Allergy Immunol. ,

Wopfner, N., Willeroider, M., Hebenstreit, D., van Ree, Ronald, Aalbers, M., Briza, P., Thalhamer, J., Ebner, C., Richter, K., Ferreira, F.

Molecular and immunological characterization of profilin from mugwort pollen.Biol. Chem. ,

Himly, M., Jahn-Schmid, B., Dedic, A., Kelemen, P., Wopfner, N., Altmann, F., van Ree, R., Briza, P., Richter, K., Ebner, C., Ferreira, F. (). Art v 1, the major allergen of mugwort pollen is a modular glycoprotein with a defensin-like and a hydroxyproline-rich domain.FASEB J /fjfje,FASEB J ,

Jahn-Schmid, B. Kelemen, P., Himly, M., Bohle, B., Fischer, G., Ferreira, F., Ebner, C. The T cell response to Art v 1, the major mugwort pollen allergen, is dominated by one epitope.J. Immunol. ,

Geisberger, R., Prlic, M., Achatz-Straussberger, G., Oberndorfer, I., Luger, E., Lamers, M., Crameri, R., Appenzeller, U., Wienands, J., Ferreira, F., Achatz, G.

Phage display based cloning of proteins interacting with the cytoplasmic tail of membrane immunoglobulins.Developmental Immunology 9: ,

Pertl, H., Himly, M., Gehwolf, R., Kriechbaumer, R., Strasser, D., Michalke, W., Richter, K., Ferreira, F., Obermeyer, G. Molecular and physiological characterisation of a protein from lily pollen grains regulating the activity of the plasma membrane H+ATPase during pollen grain germination and tube growth.
Planta ,

Ferreira F., Himly, M., Hebenstreit D., Dabrowska, M., Vollmann, U., Kraft, D., Obermeyer, G., Richter, K.

Isolation and characterization of cDNA clones coding for Mugwort (Artemisia vulgaris) Pollen AllergensInt. Arch. Allergy Immunol., ,

Simon-Nobbe, B., Kodzius, R., Kajava, A., Ferreira, F., Kungl, A., Achatz, G., Crameri, R., Ebner, C., Breitenbach, M.
Structure of an IgE-binding peptide from fungal enolases.Int. Arch. Allergy Immunol., ,

Hochreiter, R., Hartl, A., Freund, J., Valenta, R., Ferreira, F., Thalhamer J. The influence of CpG motifs on a protein or DNA-based Th2 type immune response against major pollen allergens Bet v 1a, Phl p 2 and Escherichia coli-derived ß-galactosidase.Int.

Arch. Allergy Immunol. ,

zurück


<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href=’/help/cross_references_section’ target=’_top’>More</a></p>Cross-referencesi

Protein family/group databases

Allergomei Amb p
31 Amb p 5

Family and domain databases

InterProi View protein in InterPro
IPR Amb_V_allergen
IPR Amb_V_allergen_sf
Pfami View protein in Pfam
PF Amb_V_allergen, 1 hit
PIRSFi PIRSF Amb_V_allergen, 1 hit
SMARTi View protein in SMART
SM Amb_V_allergen, 1 hit
SUPFAMi SSF SSF, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

MoreProtoNeti

Search

MobiDB: a database of protein disorder and mobility annotations

MoreMobiDBi

Search


Publikationen

Weitere Publikationen von Professor Mösges: Pubmed

Geolocation with honor to personal privacy for the Allergy Diary app — a MASK study

Samreth D, Arnavielhe S, Ingenrieth F, Bedbrook A, Onorato GL, Murray R, Almeida R, Mizani MA, Fonseca J, Costa E, Malva J, Morais-Almeida M, Pereira AM, Todo-Bom A, Menditto E, Stellato C, Ventura MT, Larenas-Linnemann D, Fuentes-Pérez JM, Huerta-Villalobos YR, Cruz AA, Stelmach R, da Silva J, Emuzyte R, Kvedariene V, Valiulis A, Annesi-Maesano I, Bosse I, Demoly P, Devillier P, Fontaine JF, Kuna P, Samolinski B, Klimek L, Mösges R, Pfaar O, Shamai S, Bewick M, Ryan D, Sheikh A, Anto JM, Cardona V, Mullol J, Valero A, Chavannes NH, Fokkens WJ, Reitsma S, Roller-Wirnsberger RE, Tomazic PV, Haahtela T, Toppila-Salmi S, Valovirta E, Makris M, Papadopoulos NG, Prokopakis EP, Psarros F, Gemicioğlu B, Yorgancioglu A, Bindslev-Jensen C, Eller E, Kull I, Wickman M, Bachert C, Hellings PW, Pugin B, Bosnic-Anticevich S, O'Hehir RE, Kolek V, Sova M, Wehner K, De Vries G, van Eerd M, Laune D, Wittmann J, Bousquet J, Poncelet P; MASK study group.

World Allergy Organ J. Jul 16;11(1) doi: /s eCollection PMID:

Conjunctival provocation tests: prediction of seasonal allergy

Schröder J, Mösges R. Curr Opin Allergy Clin Immunol. Jul doi: /ACI PMID

Impaired sports performance of athletes suffering from pollen-induced allergic rhinitis: a cross-sectional, observational survey in German athletes

Salem L, Dao VA, Shah-Hosseini K, de Marees M, Mester J, Mösges R, Vent J. J Sports Med Phys Fitness. Jul doi: /S PMID

Early nonreactivity in the conjunctival provocation test predicts beneficial outcome of sublingual immunotherapy

Köther J, Mandl A, Allekotte S, Astvatsatourov A, Chwieralski J, Liedtke JP, Pieper-Fürst U, Raskopf E, Shah-Hosseini K, Mösges R.

Clin Transl Allergy. Jul 4; doi: /sy. eCollection PMID

Elevated oxytocin and noradrenaline indicate higher stress levels in allergic rhinitis patients: Implications for the skin prick diagnosis in a pilot study

Gotovina J, Pranger CL, Jensen AN, Wagner S, Kothgassner OD, Mothes-Luksch N, Palme R, Larenas-Linnemann D, Singh J, Mösges R, Felnhofer A, Glenk LM, Jensen-Jarolim E. PLoS One. May 29;13(5):e doi: / eCollection PMID

Randomized controlled trials define shape of dose response for Pollinex Quattro Birch allergoid immunotherapy

Worm M, Higenbottam T, Pfaar O, Mösges R, Aberer W, Gunawardena K, Wessiepe D, Lee D, Kramer MF, Skinner M, Lees B, Zielen S.

Allergy. May doi: /all PMID

Reliability of a New Symptom Score in a Titrated Quantitative Conjunctival Provocation Test Supported by an Objective Photodocumentation

Pfaar O, Claßen DP, Astvatsatourov A, Klimek L, Mösges R. Int Arch Allergy Immunol. ;() doi: / Epub May PMID

Differences in Reporting the Ragweed Pollen Season Using Trends across 15 Countries

Bousquet J, Agache I, Berger U, Bergmann KC, Besancenot JP, Bousquet PJ, Casale T, d'Amato G, Kaidashev I, Khaitov M, Mösges R, Nekam K, Onorato GL, Plavec D, Sheikh A, Thibaudon M, Vautard R, Zidarn M. Int Arch Allergy Immunol. ;() doi: / Epub May 9. Review.

PMID

Daily allergic multimorbidity in rhinitis using mobile technology: A novel concept of the MASK study

Bousquet J, Devillier P, Anto JM, Bewick M, Haahtela T, Arnavielhe S, Bedbrook A, Murray R, van Eerd M, Fonseca JA, Morais Almeida M, Todo Bom A, Menditto E, Passalacqua G, Stellato C, Triggiani M, Ventura MT, Vezzani G, Annesi-Maesano I, Bourret R, Bosse I, Caimmi D, Cartier C, Demoly P, Just J, Portejoie F, Siroux V, Viart F, Bergmann KC, Keil T, Klimek L, Mösges R, Pfaar O, Shamai S, Zuberbier T, Mullol J, Valero A, Spranger O, Tomazic PV, Kowalski ML, Kuna P, Kupczyk M, Raciborski F, Samolinski B, Toppila-Salmi SK, Valovirta E, Cruz AA, Sarquis-Serpa F, da Silva J, Stelmach R, Larenas-Linnemann D, Rodriguez Gonzalez M, Burguete Cabañas MT, Kvedariene V, Valiulis A, Chavannes NH, Fokkens WJ, Ryan D, Sheikh A, Bachert C, Hellings PW, VandenPlas O, Ballardini N, Kull I, Melén E, Westman M, Wickman M, Bindslev-Jensen C, Eller E, Bosnic-Anticevich S, O'Hehir RE, Agache I, Bieber T, Casale T, Gemicioğlu B, Ivancevich JC, De Vries G, Sorensen M, Yorgancioglu A, Laune D; MACVIA working group.

Allergy. Aug;73(8) doi: /all Epub Apr Review. PMID

Ultra-short-course booster allergen immunotherapy

Pfaar O, Pieper-Fürst U, Mösges R. Immunotherapy. Jun;10(7) doi: /imt Epub Mar PMID

Short course of grass allergen peptides immunotherapy over 3 weeks reduces seasonal symptoms in allergic rhinoconjunctivitis with/without asthma: A randomized, multicenter, double-blind, placebo-controlled trial

Mösges R, Bachert C, Panzner P, Calderon MA, Haazen L, Pirotton S, Wathelet N, Durham SR, Bonny MA, Legon T, von Frenckell R, Pfaar O, Shamji MH.

Allergy. Mar 7. doi: /all PMID

Clinical trials in allergen immunotherapy: current concepts and future needs

Pfaar O, Alvaro M, Cardona V, Hamelmann E, Mösges R, Kleine-Tebbe J. Allergy. Feb doi: /all Review. PMID

EAACI Position paper on the standardization of nasal allergen challenges

Augé J, Vent J, Agache I, Airaksinen L, Campo Mozo P, Chaker A, Cingi C, Durham S, Fokkens W, Gevaert P, Giotakis A, Hellings P, Herknerova M, Hox V, Klimek L, La Melia C, Mullol J, Muluk NB, Muraro A, Naito K, Pfaar O, Riechelmann H, Rondon C, Rudenko M, Samolinski B, Tasca I, Tomazic P, Vogt K, Wagenmann M, Yeryomenko G, Zhang L, Mösges R.

Allergy. Aug;73(8) doi: /all Epub Mar PMID

EAACI Guidelines on Allergen Immunotherapy: Allergic rhinoconjunctivitis

Roberts G, Pfaar O, Akdis CA, Ansotegui IJ, Durham SR, Gerth van Wijk R, Halken S, Larenas-Linnemann D, Pawankar R, Pitsios C, Sheikh A, Worm M, Arasi S, Calderon MA, Cingi C, Dhami S, Fauquert JL, Hamelmann E, Hellings P, Jacobsen L, Knol EF, Lin SY, Maggina P, Mösges R, Oude Elberink JNG, Pajno GB, Pastorello EA, Penagos M, Rotiroti G, Schmidt-Weber CB, Timmermans F, Tsilochristou O, Varga EM, Wilkinson JN, Williams A, Zhang L, Agache I, Angier E, Fernandez-Rivas M, Jutel M, Lau S, van Ree R, Ryan D, Sturm GJ, Muraro A.

Allergy. Apr;73(4) doi: /all Epub Oct PMID

Treatment of allergic rhinitis using mobile technology with real-world data: The MASK observational pilot study

Bousquet J, Devillier P, Arnavielhe S, Bedbrook A, Alexis-Alexandre G, van Eerd M, Murray R, Canonica GW, Illario M, Menditto E, Passalacqua G, Stellato C, Triggiani M, Carreiro-Martins P, Fonseca J, Morais Almeida M, Nogueira-Silva L, Pereira AM, Todo Bom A, Bosse I, Caimmi D, Demoly P, Fontaine JF, Just J, Onorato GL, Kowalski ML, Kuna P, Samolinski B, Anto JM, Mullol J, Valero A, Tomazic PV, Bergmann KC, Keil T, Klimek L, Mösges R, Shamai S, Zuberbier T, Murphy E, McDowall P, Price D, Ryan D, Sheikh A, Chavannes NH, Fokkens WJ, Kvedariene V, Valiulis A, Bachert C, Hellings PW, Kull I, Melen E, Wickman M, Bindslev-Jensen C, Eller E, Haahtela T, Papadopoulos NG, Annesi-Maesano I, Bewick M, Bosnic-Anticevich S, Cruz AA, De Vries G, Gemicioglu B, Larenas-Linnemann D, Laune D, Mathieu-Dupas E, O'Hehir RE, Pfaar O, Portejoie F, Siroux V, Spranger O, Valovirta E, VandenPlas O, Yorgancioglu A.

Allergy. Jan doi: /all [Epub ahead of print] Review. PMID

Lolium perenne peptide immunotherapy is well tolerated and elicits a protective B-cell response in seasonal allergic rhinitis patients

Mösges R, Koch AF, Raskopf E, Singh J, Shah-Hosseini K, Astvatsatourov A, Hauswald B, Yarin Y, Corazza F, Haazen L, Pirotton S, Allekotte S, Zadoyan G, Legon T, Durham SR, Shamji MH. Allergy. Jun;73(6) doi: /all Epub Feb PMID


<p>This section displays by default the canonical protein sequence and upon request every isoforms described in the entry.

It also includes information pertinent to the sequence(s), including <a href=»»>length</a> and <a href=»»>molecular weight</a>. The information is filed in diverse subsections. The current subsections and their content are listed below:<p><a href=’/help/sequences_section’ target=’_top’>More</a></p>Sequencei

<p>This subsection of the <a href=»»>Sequence</a> section indicates if the <a href=»»>canonical sequence</a> displayed by default in the entry is finish or not.<p><a href=’/help/sequence_status’ target=’_top’>More</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href=»»>Sequence</a> section indicates if the <a href=»»>canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href=’/help/sequence_processing’ target=’_top’>More</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

Natural variant

Feature key Position(s) DescriptionActions Graphical view Length
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href=’/help/variant’ target=’_top’>More</a></p>Natural varianti 59 E → K in clone A3. 1

Sequence databases


RELATED VIDEO: