What is a skin allergy
Common symptoms of an allergic reaction include:
- swollen lips, tongue, eyes or face
- tummy pain, feeling ill, vomiting or diarrhoea
- a raised, itchy, red rash (hives)
- sneezing and an itchy, runny or blocked nose (allergic rhinitis)
- itchy, red, watering eyes (conjunctivitis)
- wheezing, chest tightness, shortness of breath and a cough
- dry, red and cracked skin
The symptoms vary depending on what you’re allergic to and how you come into contact with it.
For example, you may have a runny nose if exposed to pollen, develop a rash if you own a skin allergy, or feel sick if you eat something you’re allergic to.
See your GP if you or your kid might own had an allergic reaction to something.
They can assist determine whether the symptoms are caused by an allergy or another condition.
Read more about diagnosing allergies.
Severe allergic reaction (anaphylaxis)
In rare cases, an allergy can lead to a severe allergic reaction, called anaphylaxis or anaphylactic shock, which can be life threatening.
This affects the whole body and usually develops within minutes of exposure to something you’re allergic to.
Signs of anaphylaxis include any of the symptoms above, as well as:
Anaphylaxis is a medical emergency that requires immediate treatment.
Read more about anaphylaxis for information about what to do if it occurs.
Sheet final reviewed: 22 November
Next review due: 22 November
People who suffer itching with no clear cause may own previously unrecognized immune system defects.
In a little study of such patients, researchers from the Middle for the Study of Itch at Washington University School of Medicine in St. Louis identified immune system irregularities that may immediate the urge to scratch.
The findings are reported in the May issue of The Journal of the American Academy of Dermatology.
“As doctors, we throw things love antihistamines, ointments and lotions at patients who suffer chronic itching, but if there is something profoundly abnormal about the immune system — as it appears there is — then we can’t solve the itching until we address those underlying causes,” said principal investigator Brian S.
Kim, MD, an assistant professor of medicine in the Division of Dermatology.
“The immune system needs to be in balance, and we hope to discover ways to restore that balance in patients with this extremely debilitating condition.”
The researchers took blood samples and skin biopsies from a little sample of patients — only four are reported in the study — to glance for immune problems. They found “an incredible quantity of dysfunction,” Kim said, adding that he has seen similar defects in numerous additional patients not included in the current study.
The four patients researchers zeroed in on were ages 75 to In blood samples, three of those four had high levels of the protein IgE — an immunoglobulin that is a marker of inflammation.
Immunoglobulins are antibodies deployed by the immune system to fight infections. Elevated levels of IgE often are seen in patients with allergies.
The researchers also noted extremely low levels of an immunoglobulin known as IgG; abnormally low counts of a type of immune cell called a CD8 T-cell; and an elevated number of immune cells called eosinophils, which are markers of allergic inflammation.
“Curiously, none of these patients had any history of allergic disorders,” Kim said.
“We often see similarly high counts of eosinophils in patients with eczema, but the patients we studied didn’t own eczema. They didn’t even own a rash. Only itching.”
Kim explained that dermatologists frequently take skin biopsies when a patient has a rash, but with chronic itching of unknown origin, which doctors call chronic idiopathic pruritis, there is nothing evident to biopsy.
The study’s first author, Amy Xu, a medical student in Kim’s lab, said most patients with this type of unexplained, chronic itching tend to be older and develop itching problems later in life.
“It may be caused by some sort of wear and tear on the immune system,” Xu said.
Because of the little number of patients in the study, it’s too soon to draw firm conclusions, but the itching may be an indication that something else in the body is going incorrect, Kim said.
“We own begun working on a mouse model in which the animals own similar defects,” he said.
“We desire to study whether these changes in the immune system create only itching or whether they could be signs that some other problem is present.”
Washington University School of Medicine’s 2, employed and volunteer faculty physicians also are the medical staff of Barnes-Jewish and St. Louis Children’s hospitals. The School of Medicine is one of the leading medical research, teaching and patient-care institutions in the nation, currently ranked sixth in the nation by U.S. News & World Report. Through its affiliations with Barnes-Jewish and St.
Louis Children’s hospitals, the School of Medicine is linked to BJC HealthCare.
Originally published by the School of Medicine
First author Amy Xu and principal investigator Brian S. Kim, MD, found that immune system defects may assist explain chronic itching in some patients. (Photo: Robert Boston/School of Medicine)
At Carolina Asthma & Allergy Middle, we’re committed to providing the highest quality asthma and allergy care in North and South Carolina.
To better serve both states, our Rock Hill location is located near the South Carolina border, making it easily accessible to South Carolina residents in Rock Hill, Fort Mill, and Lake Wylie as well as North Carolina areas such as Pineville.
We own five medical experts on hand at our Rock Hill office, including Natasha Laungani, FNP-C; S. Nicole Chadha, MD; Roopen R.
Patel, MD; Susan I. Hungness, MD; and Glenn W.
Errington, MD. Dr. Laungani, who is exclusive to our Rock Hill location, studied at the University of Kentucky and the University of Cincinnati. Dr. Errington specializes in children over two years ancient and adults. He received certifications through the American Board of Internal Medicine and the American Board of Allergy and Immunology.
You’ll discover our shot room at our Rock Hill office as well, which is open until p.m.
on weekdays. This is for our allergy patients dealing with skin allergies, food allergies, insect allergies, and more. Our patients who need allergy treatment or asthma treatment can set up an appointment for any day of the week until 5 p.m.
with one of our specialists. The phone number for our Carolina Asthma & Allergy Middle, including our Rock Hill office, is
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