What essential oil is good for allergy relief

Essential oils are not regulated by the FDA and do not own to meet any purity standards. When purchasing essential oils, glance for a supplier who either distills their own material or deals directly with reputable distillers and uses gas chromatography and mass spectrometry (GC/MS) to analyze the quality of the product.

When buying pure frankincense essential oil, check the label for its Latin name, Boswellia carterii or Boswellia sacra.

No other oils ingredients should be listed. If you see another oil, such as fractionated coconut oil, jojoba oil, or sweet almond oil, the frankincense is diluted and should not be used in a diffuser.

Essential oils should be packaged in a dark amber or cobalt bottle and stored out of sunlight.


Dosage and Preparation

There is no standard or recommended dose for frankincense essential oil.

When a drop or two is combined with a carrier oil (such as jojoba, sweet almond, or avocado oil), frankincense essential oil can be applied to the skin or added to baths in little amounts.

Frankincense essential oil can also be inhaled after sprinkling a drop or two of the oil onto a cloth or tissue, or by using an aromatherapy diffuser or vaporizer.

In aromatherapy, several other essential oils are often used in combination with frankincense.


Health Benefits

While preliminary research suggests that frankincense essential oil may offer certain health benefits, there is currently a lack of research testing the health effects of frankincense oil. A component in frankincense, boswellic acid, has been studied for its anti-inflammatory and anti-tumor properties. Here's a glance at the science.

Cancer

Laboratory research on human cells indicates that frankincense essential oil may possess immune-stimulating and cancer-fighting properties that could aid in the protection against breast cancer and pancreatic cancer. However, it's significant to note that these studies were conducted in a lab (and not in people) and didn't test the aromatherapeutic use of frankincense oil.

More research is needed.

A combination of essential oils including frankincense oil may assist sleep in people with cancer, according to a study published in Complementary Therapies in Clinical Practice in  For the study, people with cancer were given personal inhaler devices containing essential oils.

Of those who used the device, 64% had an improvement of at least one point on the sleep scale. One essential oil mix found effective included frankincense (Boswellia carterii), mandarin (Citrus reticulata), and lavender (Lavandula angustifolia).

What essential oil is excellent for allergy relief

Osteoarthritis

Frankincense appears to own anti-inflammatory properties and several studies own examined its use for osteoarthritis and knee pain.

One review of published studies found Boswellia serrata extract shows clinically significant pain reduction for short-term use. However, studies showing its efficacy for long-term pain reduction are lacking.


Other Questions

I own type 2 diabetes. Can frankincense essential oil lower blood sugar?

Despite its purported use as an anti-diabetic agent, a placebo-controlled trial published in the Journal of Evidence-Based Integrative Medicine in found frankincense essential oil did not own any significant blood sugar lowering effects over a placebo.

Is it safe to ingest frankincense essential oil?

While some essential oil companies recommend ingesting frankincense essential oil for a wide variety of health ailments, there is no evidence to support its safety or efficacy.

If you select to ingest essential oils, be certain you are using pure oils and follow the manufacturer's directions carefully and discuss it further with your doctor.

Copyright©The Author(s) Published by Baishideng Publishing Group Inc. Every rights reserved.

World J Dermatol.May 2, ;6(2):
Published online May 2, doi: /wjd.v6.i

Cutaneous implications of essential oils

Ramya Vangipuram, Lisa Mask-Bull, Soo Jung Kim

Ramya Vangipuram, Center for Clinical Studies, Webster, TX , United States

Lisa Mask-Bull, Soo Jung Kim, Department of Dermatology, Texas Tech University Health Sciences Middle, Lubbock, TX , United States

ORCID number: $[AuthorORCIDs]

Author contributions: Vangipuram R, Mask-Bull L and Kim SJ contributed equally to this work; Vangipuram R wrote the paper; Mask-Bull L developed the thought and designed the outline; Kim SJ performed a critical revision of the manuscript.

Conflict-of-interest statement: Every authors declare no conflict of interest.

Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers.

It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC ) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on diverse terms, provided the original work is properly cited and the use is non-commercial. See:

Correspondence to: Ramya Vangipuram, MD, Middle for Clinical Studies, N. Texas Ave, Webster, TX , United States.

Telephone: + Fax: +

Received: October 20,
Peer-review started: October 24,
First decision: December 1,
Revised: January 8,
Accepted: February 10,
Article in press: February 13,
Published online: May 2,

INTRODUCTION

Essential oils (EOs) are complicated volatile substances extracted from plants, and used in food, cosmetic, and perfume industries. They own gained the attention of the medical community for their biologically athletic effects and therapeutic potential for numerous illnesses.

In addition, EOs are also experiencing a tremendous growth in aromatherapy and home use for their reported health benefits[1]. EOs are well-known allergens and photosensitizers; however, there is a paucity of data on the dermal exposure of essential oil use in the United States. In addition, the production and use of EOs is not currently standardized or regulated and may pose an occupational hazard for those with shut and repeated contact with EOs. With increasing popularity of essential oil consumption, clinicians can expect to come across more cases of cutaneous and systemic reactions to these complicated substances. This review provides the most updated and relevant scientific information related essential oil use, primarily pertaining to cutaneous involvement.

BACKGROUND

EOs are secondary metabolites found in plants[1].

They are derived from plant material, such as leaves, stems, flowers, bark, and roots[1]. Common methods used to extract the components include steam distillation, or mechanical expression; oils produced with the aid of chemical solvents are not considered true EOs[1]. The major chemical composition of EOs includes terpenes, esters, aldehydes, ketones, alcohols, phenols, and oxides[2]. A given essential oil contains varying amounts of each of these compounds, which imparts a specific perfume and determines its therapeutic characteristics[2].

In contrast, a perfume is chemically made to mimic the smell of a plant or flower.

EOs can be divided into two main distinct biosynthetic origins: The terpenes and terpenoids, and the aromatic and aliphatic components[3]. There is grand interest in the main biologically athletic component of EOs — terpenes and terpenoids. Terpenes are a large and diverse class of organic compounds that consist of five-carbon bases[4]. Some terpenes, such as the diterpenes, are the building blocks for biologically athletic compounds such as retinol, retinal, and taxol[1]. Diterpenoids own antioxidant, antimicrobial, anticancer, anti-inflammatory, wound healing, antihypertensive, analgesic, and anxiolytic activities[].

APPLICATIONS OF EOS

Currently, of the approximately EOs that own been described, are commercially important[8,9].

The use of EOs is common in food flavoring, perfume, and cosmetic industries. The United States Food and Drug istration has classified most EOs as “generally recognized as safe” at specified concentration limits[3].

EOs comprise the key ingredient in aromatherapy, which is rapidly growing in popularity worldwide[]. Numerous spas, massage therapists, and practitioners of alternative medicine provide aromatherapy.

The most commonly used EOs in aromatherapy include patchouli, cedarwood, lavender, tea tree oil, along with citrus-scented oils such as bergamot, lemon, and orange oils (Table 1). The oils are generally applied to the skin, but can also be given orally, by inhalation, or by diffusion through the air. Currently, aromatherapy products do not need approval by the FDA[13].

Little is known about consumption habits and exposure to EOs, especially in the United States.

The most comprehensive study of usage patterns was a study, which focused on the 12 most types of EOs among participants in France[14]. Information about types of EOs used, skin areas exposed, frequencies and quantities were collected. Lavender (Lavanda) species are the most used EOs among both females and males, followed by Eucalyptus oil (Table 2)[14]. The study notably pointed out the increased prevalence of female users for almost every types of Eos[14]. In addition, females tend to apply EOs on their face and neck, while males applied the products on the chest[14].

MEDICINAL USES

EOs are composed of numerous biologically athletic molecules, which may own promising therapeutic benefits in numerous diseases and ailments.

EOs own been recognized for their antibacterial, antiviral, antifungal, and insecticidal properties, which led to their acceptance and wide-spread use in the food industry[]. Pre-clinical studies own shown that in addition to aforementioned properties, EOs also protest potent anti-inflammatory, and antioxidant activity[]. Because of the grand number and variety of constituents, EOs do not own specific cellular targets. They exert their cytotoxic effects through disruptions in the structure and functions of key intracellular lipids and proteins[2]. In eukaryotic cells, EOs can change the fluidity of membranes, which become abnormally permeable resulting in leakage of radicals, cytochrome C, calcium ions and proteins[2].

Permeabilization of outer and inner mitochondrial membranes leads to cell death through apoptosis and necrosis[2]. Similar cytotoxic effects were observed in vitro in numerous gram positive and gram negative bacteria of relevance to the food industry including S. aureus and E. coli[2].

Bottom of form

Of every the EOs, tea tree oil (TTO) is arguably the most recognized and investigated compound in dermatology. Numerous studies own demonstrated its tolerability and efficacy and against P.

acnes[]. A singe-blind randomized controlled trial (RCT) in patients showed that 5% TTO gel has a comparable efficacy to that 5% benzoyl peroxide lotion[22]. In , a double-blind RCT was performed in 60 patients with mild to moderate facial acne vulgaris[23]. A significant difference between TTO gel and placebo was observed based on decreases in entire lesion counts and acne severity index scores[23]. Most recently, the results of a phase II pilot study assessing tea tree oil for the treatment of mild to moderate acne further demonstrated its efficacy, and favorable side-effect profile[24].

No serious adverse events were reported in this study and side effects were limited to self-resolving peeling, dryness and scaling[24]. In addition, tea tree oil has shown promising results for other common dermatologic ailments such as seborrheic dermatitis[]. A single-blind parallel controlled trial of patients with mild to moderate dandruff showed that the use of 5% TTO shampoo showed 41% improvement in dandruff, as measured by quadrant-area-severity score, compared with 11% in the placebo group (P < )[27].

EOs own also been studied for the treatment of alopecia areata.

A double-blind RCT involving 86 patients showed that a mixture of thyme, rosemary, lavender, and cedarwood EOs massaged into patients’ scalps produced significant improvement when compared with the carrier oils alone (improvement in 54% and 21% of patients, respectively, P = )[28]. The efficacy of the treatment was evaluated at initial assessment and 3 and 7 mo after treatment by dermatologists’ visual scoring of photographs and a computerized analysis of traced areas of alopecia[28].

However, the study had limited external validity, as the extent and severity of the alopecia areata in the subjects were not mentioned. At this time, there are no further clinical trials using EOs for alopecia areata.

There is little doubt that EOs may own grand relevance to the field of dermatology, and more studies should be performed given every of their in vitro findings. Further work on the antimicrobial, antiviral and antifungal effects of EOs may own immense potential in the treatment of dermatological diseases. Indeed, a study showed that a combination of TTO with iodine was superior to iodine alone in the treatment of molluscum contagiosum virus in 53 children[29].

What essential oil is excellent for allergy relief

Moreover, EOs may own benefits in other cutaneous maladies, such as hyperpigmentation. The efficacy of α-bisabolol, a terpene derivative of the essential oil of Matricaria chamomilla, exerts an inhibitory effect on melanogenesis[30]. In a study, α-bisabolol was evaluated in an 8-wk clinical trial of 28 Asian females, and led to a significant decrease in hyperpigmentation[31].

ADVERSE EFFECTS

While safety testing on EOs has shown minimal adverse effects, the use of EOs still poses risks and allergic responses that clinicians should be aware of.

Under normal conditions of established use, most oils appear to own a excellent safety profile[12]. The majority of adverse events are mild, but serious toxic reactions from some EOs own been observed, including abortions or abnormalities in pregnancy, neurotoxicity manifesting as seizures or retardation of baby development, bronchial hyperreactivity, and hepatotoxicity[12].

What essential oil is excellent for allergy relief

Accidental ingestion by young children has occasionally proved fatal[32]. Repeated exposure to topical lavender and tea tree oils was associated with the development of prepubertal gynecomastia in a case-series of 3 subjects[33]. This outcome was reversible upon discontinuation of the oils, and was attributed to the mild estrogenic and anti-androgenic activities of lavender and tea tree oils[33].

Notably, the majority of adverse effects of EOs are cutaneous in nature. The field of dermatology has encountered an increase in the frequency of allergic reactions to EOs, likely secondary to the growing popularity of topical use of EOs[12].

EOs are known sensitizers, and there is extensive evidence linking them to cases of contact allergy and allergic contact dermatitis[34,35]. One case of airborne contact dermatitis secondary to sensitization after inhaled aromatherapy has also been described[36]. As EOs age, they are often oxidized so their chemical composition changes, and may become more allergenic or prone to irritation[13].

What essential oil is excellent for allergy relief

The most common allergens are ylang-ylang oils, lemongrass oil, jasmine absolute, sandalwood oil, and clove oil[13]. However, in clinical practice, it may be hard to identify specific EOs in numerous cases. For example, in aromatherapy, the practitioner commonly uses undefined mixtures of EOs without specifying the plant sources.

In addition, numerous EOs contain chemicals prone to causing sensitization, including limonene, linalool, citral, and cinnamyl alcohol (Table 3)[14].

This is most commonly seen with citrus oils, such as bergamot, lemon, lime, and orange, which contain foucoramins, in addition to limonene, linalool, and citral. Linalool, a terpene derivative found in numerous EOs, is the most sensitizing components in numerous EOs[36]. It is a fragrant chemical also found in lavender, ylang-ylang, and jasmine oils[36]. Cinnamyl alcohol is found in patchouli oil[15]. Factors influencing risk of photo-sensitization also include the quantity of product applied and the area of exposure.

This is significant as the major study determining exposure patterns of topical essential oil use found that females tend to apply to areas such as the face and neck, thus placing themselves at greater risk of photosensitive reactions[14].

NEED FOR FURTHER RESEARCH

Although it is well established that allergic contact dermatitis can result from essential oil use, the allergens in EOs are largely unknown.

What essential oil is excellent for allergy relief

Moreover, patch testing currently does not provide precise or particularly dependable information on EOs, as numerous EOs lack standardization in manufacturing and production[37]. Finally, larger scale studies on exposure patterns are needed to reliably estimate the use of EOs. Numerous patients struggle with chronic cutaneous diseases and often wish to attempt to “natural” or “alternative” therapies, without being aware of the potential allergenic side effects.

CONCLUSION

The use of EOs, which are complicated volatile substances with strong odors, has endless been established in the perfume and cosmetic industries.

In addition, EOs own notable effects as antimicrobial agents, and are widely used in food industries. In recent times, EOs in the form of aromatherapy own experienced a resurgence in their popularity. They are notable for causing allergic and photosensitivity reactions, along with serious but rarely occurring side effects. More controlled clinical studies are needed to determine the benefits and risks of plant-derived products, especially EOs, in dermatology. This review describes historical and current results from scientific studies of essential oil components and highlights the areas in need of further research.

Footnotes

Manuscript source: Invited manuscript

Specialty type: Dermatology

Country of origin: United States

Peer-review report classification

Grade A (Excellent): A

Grade B (Very good): B, B

Grade C (Good): C

Grade D (Fair): 0

Grade E (Poor): 0

P- Reviewer: Chen GS, Kaliyadan F, Manolache L, Vasconcellos C S- Editor: Ji FF L- Editor: A E- Editor: Lu YJ

References

1. Islam MT,da Mata AM,de Aguiar RP,Paz MF,de Alencar MV,Ferreira PM,de Carvalho Melo-Cavalcante AA.Therapeutic Potential of Essential Oils Focusing on Diterpenes.Phytother Res.;30 [PubMed][DOI]
2. Bakkali F,Averbeck S,Averbeck D,Idaomar M.Biological effects of essential oils—a review.Food Chem Toxicol.;46 [PubMed][DOI]
3. Pichersky E,Noel JP,Dudareva N.Biosynthesis of plant volatiles: nature’s diversity and ingenuity.Science.; [PubMed][DOI]
4. Llana-Ruiz-Cabello M,Pichardo S,Maisanaba S,Puerto M,Prieto AI,Gutiérrez-Praena D,Jos A,Cameán AM.In vitro toxicological evaluation of essential oils and their main compounds used in athletic food packaging: A review.Food Chem Toxicol.;81 [PubMed][DOI]
5. Devappa RK,Makkar HPS,Becker K.

Jatropha diterpenes: a review.J Am Oil Chem Soc.;88 [PubMed][DOI]

6. Cheenpracha S,Yodsaoue O,Karalai C,Ponglimanont C,Subhadhirasakul S,Tewtrakul S,Kanjana-opas A.Potential anti-allergic ent-kaurene diterpenes from the bark of Suregada multiflora.Phytochemistry.;67 [PubMed][DOI]
7. Cho JH,Lee JY,Sim SS,Whang WK,Kim CJ.Inhibitory effects of diterpene acids from root of Aralia cordata on IgE-mediated asthma in guinea pigs.Pulm Pharmacol Ther.;23 [PubMed][DOI]
8. Gyawali R,Ibrahim SA.Natural products as antimicrobial agents.Food Contr.; [PubMed][DOI]
9. Hyldgaard M,Mygind T,Meyer RL.Essential oils in food preservation: mode of action, synergies, and interactions with food matrix components.Front Microbiol.;3 [PubMed][DOI]
Rhind JP.Essential Oils.

A Handbook for Aromatherapy Practice. 2nd edition.London: Singing Dragon ; . [PubMed][DOI]

Lawless J.The Encyclopedia of Essential Oils. 2nd edition.London: Harper Thorsons ; . [PubMed][DOI]
de Groot AC,Schmidt E.Essential Oils, Part I: Introduction.Dermatitis.;27 [PubMed][DOI]
Aromatherapy and Essential Oils (PDQ®): Health Professional Version.PDQ Integrative, Alternative, and Complementary Therapies Editorial Board.Bethesda (MD): National Cancer Institute (US); ; Apr 8.

[PubMed][DOI]

Dornic N,Ficheux AS,Roudot AC,Saboureau D,Ezzedine K.Usage patterns of aromatherapy among the French general population: A descriptive study focusing on dermal exposure.Regul Toxicol Pharmacol.;76 [PubMed][DOI]
Sung SY,Sin LT,Tee TT Soo-Tueen B,Rahmat AR,Rahman WA,Ann-Chen T,Vikhraman K.Antimicrobial agents for food packaging applications.Trends Food Sci Technol.;33 [PubMed][DOI]
Angioni A,Barra A,Coroneo V,Dessi S,Cabras P.Chemical composition, seasonal variability, and antifungal activity of Lavandula stoechas L.

ssp.

What essential oil is excellent for allergy relief

stoechas essential oils from stem/leaves and flowers.J Agric Food Chem.;54 [PubMed][DOI]

Bajpai VK,Baek KH,Kang SC.Control of Salmonella in foods by using essential oils: a review.Food Res Int.;45 [PubMed][DOI]
Abbaszadeh G,Srivastava C,Walia S.Insecticidal and antifeedant activities of clerodane diterpenoids isolated from the Indian bhant tree, Clerodendron infortunatum, against the cotton bollworm, Helicoverpa armigera.J Insect Sci.;14 [PubMed][DOI]
Tang W,Wei X,Xu H,Zeng D,Long L.Deoxyitol A, a new insecticidal isoryanodane diterpene from the seeds of Itoa orientalis.Fitoterapia.;80 [PubMed][DOI]
Roby MHH,Sarhana MA,Selima KAH,Khalela KI.Evaluation of antioxidant activity, entire phenols and phenolic compounds in thyme (Thymus vulgaris L.), sage (Salvia officinalis L.), and marjoram (Origanum majorana L.) extracts.Ind Crops Prod.;43 [PubMed][DOI]
Teixeira B,Marques A,Ramos C,Batista I,Serrano C,Matos O,Neng NR,Nogueira J,Saraiva JA,Nunes ML.European pennyroyal (Mentha pulegium) from Portugal: chemical composition of essential oil and antioxidant and antimicrobial properties of extracts and essential oil.Ind Crops Prod.;36 [PubMed][DOI]
Bassett IB,Pannowitz DL,Barnetson RS.A comparative study of tea-tree oil versus benzoylperoxide in the treatment of acne.Med J Aust.; [PubMed][DOI]
Enshaieh S,Jooya A,Siadat AH,Iraji F.The efficacy of 5% topical tea tree oil gel in mild to moderate acne vulgaris: a randomized, double-blind placebo-controlled study.Indian J Dermatol Venereol Leprol.;73 [PubMed][DOI]
Malhi HK,Tu J,Riley TV,Kumarasinghe SP,Hammer KA.Tea tree oil gel for mild to moderate acne; a 12 week uncontrolled, open-label phase II pilot study.Australas J Dermatol.;Epub ahead of print.

[PubMed][DOI]

Gupta AK,Nicol K,Batra R.Role of antifungal agents in the treatment of seborrheic dermatitis.Am J Clin Dermatol.;5 [PubMed][DOI]
Waldroup W,Scheinfeld N.Medicated shampoos for the treatment of seborrheic dermatitis.J Drugs Dermatol.;7 [PubMed][DOI]
Satchell AC,Saurajen A,Bell C,Barnetson RS.Treatment of dandruff with 5% tea tree oil shampoo.J Am Acad Dermatol.;47 [PubMed][DOI]
Hay IC,Jamieson M,Ormerod AD.Randomized trial of aromatherapy.

Successful treatment for alopecia areata.Arch Dermatol.; [PubMed][DOI]

Markum E,Baillie J.Combination of essential oil of Melaleuca alternifolia and iodine in the treatment of molluscum contagiosum in children.J Drugs Dermatol.;11 [PubMed][DOI]
Kim S,Lee J,Jung E,Huh S,Park JO,Lee JW,Byun SY,Park D.Mechanisms of depigmentation by alpha-bisabolol.J Dermatol Sci.;52 [PubMed][DOI]
Lee J,Jun H,Jung E,Ha J,Park D.Whitening effect of alpha-bisabolol in Asian women subjects.Int J Cosmet Sci.;32 [PubMed][DOI]
Tisserand R,Young R.Essential Oil Safety.USA: Churchill Livingstone Elsevier ; .

[PubMed][DOI]

Henley DV,Lipson N,Korach KS,Bloch CA.Prepubertal gynecomastia linked to lavender and tea tree oils.N Engl J Med.; [PubMed][DOI]
Bilsland D,Strong A.Allergic contact dermatitis from the essential oil of French marigold (Tagetes patula) in an aromatherapist.Contact Dermatitis.;23 [PubMed][DOI]
Lapeere H,Boone B,Verhaeghe E,Ongenae K,Lambert J.Contact dermatitis caused by lovage (Levisticum officinalis) essential oil.Contact Dermatitis.;69 [PubMed][DOI]
Schaller M,Korting HC.Allergic airborne contact dermatitis from essential oils used in aromatherapy.Clin Exp Dermatol.;20 [PubMed][DOI]
Hagvall L,Christensson JB.Patch Testing with Main Sensitizers Does Not Detect Every Cases of Contact Allergy to Oxidized Lavender Oil.Acta Derm Venereol.;96 [PubMed][DOI]


Possible Side Effects

Research is needed to assess the potential benefits and risks.

Ingesting frankincense essential oil may own toxic effects and isn't recommended, unless under a doctor's supervision.

In addition, some individuals may experience irritation or an allergic reaction when applying frankincense essential oil to the skin. A skin patch test should be done before using any new essential oil. Additionally, essential oils shouldn't be applied to skin undiluted.

Pregnant or nursing women and children should consult their health care providers before using essential oils.

It's also significant to note that self-treating a condition with frankincense essential oil and avoiding or delaying standard care may own serious consequences.


RELATED VIDEO: